Skip to main content
Top
Published in: BMC Women's Health 1/2021

Open Access 01-12-2021 | Misoprostol | Case report

Administration of oxytocin antagonist at the same time as using a Foley catheter with cotton swab before embryo transfer for cervical stenosis

Author: Heesuk Chae

Published in: BMC Women's Health | Issue 1/2021

Login to get access

Abstract

Background

Embryo transfer without difficulty in a patient with cervical stenosis can be a great challenge for in vitro fertilization (IVF). We report a successful pregnancy following a frozen thawed embryo transfer after administration of an oxytocin antagonist at the same time as using a Foley catheter with cotton swab in a patient with refractory cervical stenosis.

Case presentation

A 40-year-old woman undergoing IVF. The patient’s previous embryo transfers were difficult. For every transfer, uterine manipulation was needed, force was required, and dilatation was necessary. A Foley catheter with a cotton swab was inserted into the cervical canal, atosiban was administered at the same time, and the Foley catheter was removed immediately before embryo transfer. A smooth transfer was performed without bleeding, force, uterine manipulation, or cervical dilator. The patient became pregnant and delivered by cesarean section at term.

Conclusion

This method is effective in performing atraumatic embryo transfer in patients with cervical stenosis.
Literature
1.
go back to reference Goudas VT, Hammitt DG, Damario MA, Session DR, Singh AP, Dumesic DA. Blood on the embryo transfer catheter is associated with decreased rates of embryo implantation and clinical pregnancy with the use of in vitro fertilization-embryo transfer. Fertil Steril. 1998;70:878–82.CrossRef Goudas VT, Hammitt DG, Damario MA, Session DR, Singh AP, Dumesic DA. Blood on the embryo transfer catheter is associated with decreased rates of embryo implantation and clinical pregnancy with the use of in vitro fertilization-embryo transfer. Fertil Steril. 1998;70:878–82.CrossRef
2.
go back to reference Kava-Braveman A, Martínez F, Rodríquez I, Álvarez M, Barri PN, Coroleu B. What is a difficult transfer? Analysis of 7,714 embryo transfers: the impact of maneuvers during embryo transfer on pregnancy rate and a proposal of objective assessment. Fertil Steril. 2017;107:657–63.e1.CrossRef Kava-Braveman A, Martínez F, Rodríquez I, Álvarez M, Barri PN, Coroleu B. What is a difficult transfer? Analysis of 7,714 embryo transfers: the impact of maneuvers during embryo transfer on pregnancy rate and a proposal of objective assessment. Fertil Steril. 2017;107:657–63.e1.CrossRef
3.
go back to reference Wood C, McMaster R, Rennie G, Trounson A, Leeton J. Factors influencing pregnancy rates following in vitro fertilization and embryo transfer. Fertil Steril. 1985;43:245–50.CrossRef Wood C, McMaster R, Rennie G, Trounson A, Leeton J. Factors influencing pregnancy rates following in vitro fertilization and embryo transfer. Fertil Steril. 1985;43:245–50.CrossRef
4.
go back to reference Mansour R, Aboulghar M, Serour G. Dummy embryo transfer: a technique that minimizes the problems of embryo transfer and improves the pregnancy rate in human in vitro fertilization. Fertil Steril. 1990;54:678–81.CrossRef Mansour R, Aboulghar M, Serour G. Dummy embryo transfer: a technique that minimizes the problems of embryo transfer and improves the pregnancy rate in human in vitro fertilization. Fertil Steril. 1990;54:678–81.CrossRef
5.
go back to reference Tomás C, Tikkinen K, Toumivaara L, Tapainainen JS, Martikainen H. The degree of difficulty of embryo transfer is an independent factor for predicting pregnancy. Hum Reprod. 2002;17:2632–5.CrossRef Tomás C, Tikkinen K, Toumivaara L, Tapainainen JS, Martikainen H. The degree of difficulty of embryo transfer is an independent factor for predicting pregnancy. Hum Reprod. 2002;17:2632–5.CrossRef
6.
go back to reference Wood EG, Batzer FR, Go KJ, Gutmann JN, Corson SL. Ultrasound-guided soft catheter embryo transfers will improve pregnancy rates in in-vitro fertilization. Human Reprod. 2000;15:107–12.CrossRef Wood EG, Batzer FR, Go KJ, Gutmann JN, Corson SL. Ultrasound-guided soft catheter embryo transfers will improve pregnancy rates in in-vitro fertilization. Human Reprod. 2000;15:107–12.CrossRef
7.
go back to reference Lesny P, Killick SR, Tetlow RL, Robinson J, Maguiness SD. Embryo transfer–can we learn anything new from the observation of junctional zone contractions. Hum Reprod. 1998;13:1540–6.CrossRef Lesny P, Killick SR, Tetlow RL, Robinson J, Maguiness SD. Embryo transfer–can we learn anything new from the observation of junctional zone contractions. Hum Reprod. 1998;13:1540–6.CrossRef
8.
go back to reference Dorn C, Reinsberg J, Schlebusch H, Prietl G, van der Ven H, Krebs D. Serum oxytocin concentrations during embryo transfer procedure. Eur J Obstet Gynecol Reprod Biol. 1999;87:77–80.CrossRef Dorn C, Reinsberg J, Schlebusch H, Prietl G, van der Ven H, Krebs D. Serum oxytocin concentrations during embryo transfer procedure. Eur J Obstet Gynecol Reprod Biol. 1999;87:77–80.CrossRef
9.
go back to reference Fanchin R, Righini C, Olivennes F, Taylor S, de Ziegler D, Frydman R. Uterine contractions at the time of embryo transfer alter pregnancy rates after in-vitro fertilization. Hum Reprod. 1998;13:1968–74.CrossRef Fanchin R, Righini C, Olivennes F, Taylor S, de Ziegler D, Frydman R. Uterine contractions at the time of embryo transfer alter pregnancy rates after in-vitro fertilization. Hum Reprod. 1998;13:1968–74.CrossRef
10.
go back to reference Wood EG, Batzer FR, Go KJ, Gutmann JN, Corson SL. Ultrasound-guided soft catheter embryo transfers will improve pregnancy rates in in-vitro fertilization. Hum Reprod. 2000;15:107–12.CrossRef Wood EG, Batzer FR, Go KJ, Gutmann JN, Corson SL. Ultrasound-guided soft catheter embryo transfers will improve pregnancy rates in in-vitro fertilization. Hum Reprod. 2000;15:107–12.CrossRef
11.
go back to reference Knutzen V, Stratton CJ, Sher G, McNamee PI, Huang TT, Soto-Albors C. Mock embryo transfer in early luteal phase, the cycle before IVF and embryo transfer: a descriptive study. Fertil Steril. 1992;57:156–62.CrossRef Knutzen V, Stratton CJ, Sher G, McNamee PI, Huang TT, Soto-Albors C. Mock embryo transfer in early luteal phase, the cycle before IVF and embryo transfer: a descriptive study. Fertil Steril. 1992;57:156–62.CrossRef
12.
go back to reference Sundstrom P, Wramsby H, Person PH, Leidhom P. Filled bladder simplifies human embryo transfer. Br J Obstet Gynecol. 1984;91:506–7.CrossRef Sundstrom P, Wramsby H, Person PH, Leidhom P. Filled bladder simplifies human embryo transfer. Br J Obstet Gynecol. 1984;91:506–7.CrossRef
13.
go back to reference Lewin A, Schenker JG, Avrech O, Shapira S, Safran A, Friedler S. The role of uterine straightening by passive bladder distension before embryo transfer in IVF cycles. J Assist Reprod Genet. 1997;14:32–4.CrossRef Lewin A, Schenker JG, Avrech O, Shapira S, Safran A, Friedler S. The role of uterine straightening by passive bladder distension before embryo transfer in IVF cycles. J Assist Reprod Genet. 1997;14:32–4.CrossRef
14.
go back to reference Prapas Y, Prapas N, Hatziparasidou A, Prapa S, Nijs M, Vanderzwalmen P, Vlassis G, Jones EE. The echoguided embryo transfer maximized the IVF results. Acta Eur Fertil. 1995;26:113–5.PubMed Prapas Y, Prapas N, Hatziparasidou A, Prapa S, Nijs M, Vanderzwalmen P, Vlassis G, Jones EE. The echoguided embryo transfer maximized the IVF results. Acta Eur Fertil. 1995;26:113–5.PubMed
15.
go back to reference Groutz A, Lessing B, Wolf Y, Yovel I, Azem F, Amit A. Cervical dilatation during ovum pick-up in patients with cervical stenosis: effect on pregnancy outcome in an in vitro fertilization-embryo transfer program. Fertil Steril. 1997;67:909–11.CrossRef Groutz A, Lessing B, Wolf Y, Yovel I, Azem F, Amit A. Cervical dilatation during ovum pick-up in patients with cervical stenosis: effect on pregnancy outcome in an in vitro fertilization-embryo transfer program. Fertil Steril. 1997;67:909–11.CrossRef
16.
go back to reference Abusheikha N, Lass A, Akagbosu F, Brinsden P. How useful is cervical dilatation in patients with cervical stenosis who are participating in an in vitro fertilization-embryo transfer program? The Bourn Hall experience. Fertil Steril. 1999;72:610–2.CrossRef Abusheikha N, Lass A, Akagbosu F, Brinsden P. How useful is cervical dilatation in patients with cervical stenosis who are participating in an in vitro fertilization-embryo transfer program? The Bourn Hall experience. Fertil Steril. 1999;72:610–2.CrossRef
17.
go back to reference Prapas N, Prapas Y, Panagiotidis S, Prapa S, Vanderzwalmen P, Makedos G. Cervical dilatation has a positive impact on the outcome of IVF in randomly assigned cases having two previous difficult embryo transfers. Hum Reprod. 2004;19:1791–5.CrossRef Prapas N, Prapas Y, Panagiotidis S, Prapa S, Vanderzwalmen P, Makedos G. Cervical dilatation has a positive impact on the outcome of IVF in randomly assigned cases having two previous difficult embryo transfers. Hum Reprod. 2004;19:1791–5.CrossRef
18.
go back to reference Glatstein IZ, Pang SC, McShane PM. Successful pregnancies with the use of laminaria tents before embryo transfer for refractory cervical stenosis. Fertil Steril. 1997;67:1172–4.CrossRef Glatstein IZ, Pang SC, McShane PM. Successful pregnancies with the use of laminaria tents before embryo transfer for refractory cervical stenosis. Fertil Steril. 1997;67:1172–4.CrossRef
19.
go back to reference Pabuccu R, Ceyhan ST, Onalan G, Goktolga U, Ercan CM, Selam B. Successful treatment of cervical stenosis with hysteroscopic canalization before embryo transfer in patients undergoing IVF: a case series. J Minim Invasive Gynecol. 2005;12:436–8.CrossRef Pabuccu R, Ceyhan ST, Onalan G, Goktolga U, Ercan CM, Selam B. Successful treatment of cervical stenosis with hysteroscopic canalization before embryo transfer in patients undergoing IVF: a case series. J Minim Invasive Gynecol. 2005;12:436–8.CrossRef
20.
go back to reference Noyes N. Hysteroscopic cervical canal shaving: a new therapy for cervical stenosis before embryo transfer in patients undergoing in vitro fertilization. Fertil Steril. 1999;71:965–6.CrossRef Noyes N. Hysteroscopic cervical canal shaving: a new therapy for cervical stenosis before embryo transfer in patients undergoing in vitro fertilization. Fertil Steril. 1999;71:965–6.CrossRef
21.
go back to reference Kato O, Takatsuka R, Asch RH. Transvaginal-transmyometrial embryo transfer: the Towako method; experiences of 104 cases. Fertil Steril. 1993;59:51–3.CrossRef Kato O, Takatsuka R, Asch RH. Transvaginal-transmyometrial embryo transfer: the Towako method; experiences of 104 cases. Fertil Steril. 1993;59:51–3.CrossRef
22.
go back to reference Sharif K, Afnan M, Lenton W, Bilalis D, Hunjan M, Khalaf Y. Transmyometrial embryo transfer after difficult immediate mock transcervical transfer. Fertil Steril. 1996;65:1071–4.CrossRef Sharif K, Afnan M, Lenton W, Bilalis D, Hunjan M, Khalaf Y. Transmyometrial embryo transfer after difficult immediate mock transcervical transfer. Fertil Steril. 1996;65:1071–4.CrossRef
23.
go back to reference Groutz A, Lessing JB, Wolf Y, Azem F, Yovel I, Amit A. Comparison of transmyometrial and transcervical embryo transfer in patients with previously failed in vitro fertilization-embryo transfer cycles and/or cervical stenosis. Fertil Steril. 1997;67:1073–6.CrossRef Groutz A, Lessing JB, Wolf Y, Azem F, Yovel I, Amit A. Comparison of transmyometrial and transcervical embryo transfer in patients with previously failed in vitro fertilization-embryo transfer cycles and/or cervical stenosis. Fertil Steril. 1997;67:1073–6.CrossRef
24.
go back to reference Khairy M, Shah H, Rajkhowa M. Transmyometrial versus very difficult transcervical embryo transfer: efficacy and safety. Reprod Biomed Online. 2016;32:513–7.CrossRef Khairy M, Shah H, Rajkhowa M. Transmyometrial versus very difficult transcervical embryo transfer: efficacy and safety. Reprod Biomed Online. 2016;32:513–7.CrossRef
25.
go back to reference Norman JE, Thong KJ, Baird DT. Uterine contractility and induction of abortion in early pregnancy by misoprostol and mifepristone. Lancet. 1991;16:1233–6.CrossRef Norman JE, Thong KJ, Baird DT. Uterine contractility and induction of abortion in early pregnancy by misoprostol and mifepristone. Lancet. 1991;16:1233–6.CrossRef
26.
go back to reference Moraloglu O, Tonguc E, Var T, Zeyrek T, Batioglu S. Treatment with oxytocin antagonists before embryo transfer may increase implantation rates after IVF. Reprod Biomed Online. 2010;21:338–43.CrossRef Moraloglu O, Tonguc E, Var T, Zeyrek T, Batioglu S. Treatment with oxytocin antagonists before embryo transfer may increase implantation rates after IVF. Reprod Biomed Online. 2010;21:338–43.CrossRef
Metadata
Title
Administration of oxytocin antagonist at the same time as using a Foley catheter with cotton swab before embryo transfer for cervical stenosis
Author
Heesuk Chae
Publication date
01-12-2021
Publisher
BioMed Central
Keyword
Misoprostol
Published in
BMC Women's Health / Issue 1/2021
Electronic ISSN: 1472-6874
DOI
https://doi.org/10.1186/s12905-021-01409-y

Other articles of this Issue 1/2021

BMC Women's Health 1/2021 Go to the issue