Skip to main content
Top
Published in: Journal of Cardiothoracic Surgery 1/2013

Open Access 01-12-2013 | Research article

Miniaturized cardiopulmonary bypass: the Hammersmith technique

Authors: Aziz Momin, Mansour Sharabiani, John Mulholland, Gemma Yarham, Barnaby Reeves, Jon Anderson, Gianni Angelini

Published in: Journal of Cardiothoracic Surgery | Issue 1/2013

Login to get access

Abstract

Background

Conventional Cardiopulmonary Bypass (cCPB) is a trigger of systemic inflammatory reactions, hemodilution, coagulopathy, and organ failure. Miniaturised Cardiopulmonary Bypass (mCPB) has the potential to reduce these deleterious effects. Here, we describe our standardised ‘Hammersmith’ mCPB technique, used in all types of adult cardiac operations including major aortic surgery.

Methods

The use of mCPB remains limited by the diversity of technologies which range from extremely complex, micro systems to ones very similar to cCPB. Our approach is designed around the principle of balancing the benefits of miniaturisation; reducing foreign surface area while maintaining patient safety.

Results

From January 2010 to March 2011, a single surgeon performed 184 consecutive operations (Euro score Logistic 8.4+/-9.9): 61 aortic valve replacements, 78 CABGs, 25 aortic valve replacement and CABG and 17 other procedures (major aortic surgery, re-do operations or double/triple valve replacements).
Our clinical experience suggests that:
i.
Venous drainage is optimally maintained using kinetic energy.
 
ii.
Venous collapse pressure depends on the patient’s anatomy and cannula size, but most importantly on the negative pressure generated by venous drainage.
 
iii.
The patient-prime interaction is optimised with antegrade and retrograde autologous priming, which mixes the blood and prime away from the tissues and results in a reduced oncotic destabilization.
 
iv.
mCPB is a safe and reproducible technique
 

Conclusion

The Hammersmith mCPB is a “next generation” system which uses standard commercially available components. It aims to maintain safety margin and the benefit of miniaturised system whilst reducing the human factor demands.
Appendix
Available only for authorised users
Literature
1.
go back to reference Nollert G, Schwabenland I, Maktav D, Kur F, Christ F, Fraunberger P, Reichart B, Vicol C: Miniaturized cardiopulmonary bypass in coronary artery bypass surgery: marginal impact on inflammation and coagulation but loss of safety margins. Ann Thorac Surg. 2005, 80 (6): 2326-2332. 10.1016/j.athoracsur.2005.05.080.CrossRefPubMed Nollert G, Schwabenland I, Maktav D, Kur F, Christ F, Fraunberger P, Reichart B, Vicol C: Miniaturized cardiopulmonary bypass in coronary artery bypass surgery: marginal impact on inflammation and coagulation but loss of safety margins. Ann Thorac Surg. 2005, 80 (6): 2326-2332. 10.1016/j.athoracsur.2005.05.080.CrossRefPubMed
2.
go back to reference Castiglioni A, Verzini A, Pappalardo F, Colangelo N, Torracca L, Zangrillo A, Alfieri O: Minimally invasive closed circuit versus standard extracorporeal circulation for aortic valve replacement. Ann Thorac Surg. 2007, 83 (2): 586-591. 10.1016/j.athoracsur.2006.09.039.CrossRefPubMed Castiglioni A, Verzini A, Pappalardo F, Colangelo N, Torracca L, Zangrillo A, Alfieri O: Minimally invasive closed circuit versus standard extracorporeal circulation for aortic valve replacement. Ann Thorac Surg. 2007, 83 (2): 586-591. 10.1016/j.athoracsur.2006.09.039.CrossRefPubMed
3.
go back to reference Abdel Aal M, ElNahal N, Bakir BM, Fouda M: Mini-cardiopulmonary bypass impact on blood conservation strategy in coronary artery bypass grafting. Interact Cardiovasc Thorac Surg. 2011, 12 (4): 600-604. 10.1510/icvts.2010.243055.CrossRefPubMed Abdel Aal M, ElNahal N, Bakir BM, Fouda M: Mini-cardiopulmonary bypass impact on blood conservation strategy in coronary artery bypass grafting. Interact Cardiovasc Thorac Surg. 2011, 12 (4): 600-604. 10.1510/icvts.2010.243055.CrossRefPubMed
4.
go back to reference Anastasiadis K, Argiriadou H, Kosmidis MH, Megari K, Antonitsis P, Thomaidou E, Aretouli E, Papakonstantinou C: Neurocognitive outcome after coronary artery bypass surgery using minimal versus conventional extracorporeal circulation: a randomised controlled pilot study. Heart. 2011, 97 (13): 1082-1088. 10.1136/hrt.2010.218610.CrossRefPubMed Anastasiadis K, Argiriadou H, Kosmidis MH, Megari K, Antonitsis P, Thomaidou E, Aretouli E, Papakonstantinou C: Neurocognitive outcome after coronary artery bypass surgery using minimal versus conventional extracorporeal circulation: a randomised controlled pilot study. Heart. 2011, 97 (13): 1082-1088. 10.1136/hrt.2010.218610.CrossRefPubMed
5.
go back to reference Remadi JP, Rakotoarivello Z, Marticho P, Trojette F, Benamar A, Poulain H, Tribouilloy C: Aortic valve replacement with the minimal extracorporeal circulation (Jostra MECC System) versus standard cardiopulmonary bypass: a randomized prospective trial. J Thorac Cardiovasc Surg. 2004, 128 (3): 436-441. 10.1016/j.jtcvs.2004.01.041.CrossRefPubMed Remadi JP, Rakotoarivello Z, Marticho P, Trojette F, Benamar A, Poulain H, Tribouilloy C: Aortic valve replacement with the minimal extracorporeal circulation (Jostra MECC System) versus standard cardiopulmonary bypass: a randomized prospective trial. J Thorac Cardiovasc Surg. 2004, 128 (3): 436-441. 10.1016/j.jtcvs.2004.01.041.CrossRefPubMed
6.
go back to reference Biancari F, Rimpilainen R: Meta-analysis of randomised trials comparing the effectiveness of miniaturised versus conventional cardiopulmonary bypass in adult cardiac surgery. Heart. 2009, 95 (12): 964-969. 10.1136/hrt.2008.158709.CrossRefPubMed Biancari F, Rimpilainen R: Meta-analysis of randomised trials comparing the effectiveness of miniaturised versus conventional cardiopulmonary bypass in adult cardiac surgery. Heart. 2009, 95 (12): 964-969. 10.1136/hrt.2008.158709.CrossRefPubMed
7.
go back to reference El-Essawi A, Hajek T, Skorpil J, Boning A, Sabol F, Hausmann H, Ostrovsky Y, Harringer W: A prospective randomised multicentre clinical comparison of a minimised perfusion circuit versus conventional cardiopulmonary bypass. Eur J Cardiothorac Surg. 2010, 38 (1): 91-97. 10.1016/j.ejcts.2010.01.035.CrossRefPubMed El-Essawi A, Hajek T, Skorpil J, Boning A, Sabol F, Hausmann H, Ostrovsky Y, Harringer W: A prospective randomised multicentre clinical comparison of a minimised perfusion circuit versus conventional cardiopulmonary bypass. Eur J Cardiothorac Surg. 2010, 38 (1): 91-97. 10.1016/j.ejcts.2010.01.035.CrossRefPubMed
8.
go back to reference Willcox TW, Mitchell SJ, Gorman DF: Venous air in the bypass circuit: a source of arterial line emboli exacerbated by vacuum-assisted drainage. Ann Thorac Surg. 1999, 68 (4): 1285-1289. 10.1016/S0003-4975(99)00721-3.CrossRefPubMed Willcox TW, Mitchell SJ, Gorman DF: Venous air in the bypass circuit: a source of arterial line emboli exacerbated by vacuum-assisted drainage. Ann Thorac Surg. 1999, 68 (4): 1285-1289. 10.1016/S0003-4975(99)00721-3.CrossRefPubMed
9.
go back to reference Ti LK, Goh BL, Wong PS, Ong P, Goh SG, Lee CN: Comparison of mini-cardiopulmonary bypass system with air-purge device to conventional bypass system. Ann Thorac Surg. 2008, 85 (3): 994-1000. 10.1016/j.athoracsur.2007.09.001.CrossRefPubMed Ti LK, Goh BL, Wong PS, Ong P, Goh SG, Lee CN: Comparison of mini-cardiopulmonary bypass system with air-purge device to conventional bypass system. Ann Thorac Surg. 2008, 85 (3): 994-1000. 10.1016/j.athoracsur.2007.09.001.CrossRefPubMed
Metadata
Title
Miniaturized cardiopulmonary bypass: the Hammersmith technique
Authors
Aziz Momin
Mansour Sharabiani
John Mulholland
Gemma Yarham
Barnaby Reeves
Jon Anderson
Gianni Angelini
Publication date
01-12-2013
Publisher
BioMed Central
Published in
Journal of Cardiothoracic Surgery / Issue 1/2013
Electronic ISSN: 1749-8090
DOI
https://doi.org/10.1186/1749-8090-8-143

Other articles of this Issue 1/2013

Journal of Cardiothoracic Surgery 1/2013 Go to the issue