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Published in: BMC Surgery 1/2022

Open Access 01-12-2022 | Milligan-Morgan Hemorrhoidectomy | Research

Milligan–Morgan hemorrhoidectomy vs. hemorrhoid artery ligation and recto-anal repair: a comparative study

Authors: Dimitrios Symeonidis, Michail Spyridakis, Dimitrios Zacharoulis, George Tzovaras, Athina A. Samara, Alexandros Valaroutsos, Alexandros Diamantis, Konstantinos Tepetes

Published in: BMC Surgery | Issue 1/2022

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Abstract

Background

Several surgical techniques for the treatment of hemorrhoidal disease (HD) have been proposed. However, the selection of the most proper technique for each individual case scenario is still a matter of debate. The purpose of the present study was to compare the Milligan–Morgan (MM) hemorrhoidectomy and the hemorrhoidal artery ligation and rectoanal repair (HAL–RAR) technique.

Methods

A retrospective analysis of the prospectively collected database of patients submitted to HD surgery in our department was conducted. Patients were divided into two groups, the MM group and the HAL–RAR group. Primary end points were recurrence rates and patients’ satisfaction rates. The Unpaired t test was used to compare numerical variables while the x2 test for categorical variables.

Results

A total of 124 patients were identified, submitted either to HAL–RAR or MM hemorrhoidectomy. Eight (8) patients were lost to follow up and were excluded from the analysis. Of the remaining 116 patients, 69 patients (54 males and 15 females–male / female ratio: 3.6) with a median age of 47 years old (range 18–69) were included in the HAL–RAR group while 47 patients (40 males and 7 females–male / female ratio: 5.7) with a median age of 52 years old (range 32–71) comprised the MM group. At a median follow up of 41 months (minimum 24 months–maximum 72 months), we recorded 20 recurrences (28.9%) in the HAL–RAR group and 9 recurrences in the MM group (19.1%) (p 0.229). The mean time from the procedure to the recurrence was 14.1 ± 9.74 months in the HAL–RAR group and 21 ± 13.34 months in the MM group. Patients with itching, pain or discomfort as the presenting symptoms of HD experienced statistically significantly lower recurrences (p 0.0354) and reported statistically significantly better satisfaction rates (6.72 ± 2.15 vs. 8.11 ± 1.99—p 0.0111) when submitted to MM. In the subgroup of patients with bleeding as the presenting symptom, patients satisfaction rates were significantly better (8.59 ± 1.88 vs. 6.45 ± 2.70—p 0.0013) in the HAL–RAR group.

Conclusions

In patients with pain, itching or discomfort as the presenting symptoms of HD, MM was associated with less recurrences and better patients satisfaction rates compared to HAL–RAR. In patients with bleeding as the main presenting symptom of HD, HAL–RAR was associated with better patients’ satisfaction rates and similar recurrence rates compared to MM.
Literature
1.
go back to reference Gallo G, Sacco R, Sammarco G. Epidemiology of Hemorrhoidal Disease. In: Ratto C, Parello A, Litta F, editors. Hemorrhoids Coloproctology, vol. 2. Cham: Springer; 2018. Gallo G, Sacco R, Sammarco G. Epidemiology of Hemorrhoidal Disease. In: Ratto C, Parello A, Litta F, editors. Hemorrhoids Coloproctology, vol. 2. Cham: Springer; 2018.
3.
go back to reference Goenka MK, Kochhar R, Nagi B, Mehta SK. Rectosigmoid varices and other mucosal changes in patients with portal hypertension. Am J Gastroenterol. 1991;86:1185–9. Goenka MK, Kochhar R, Nagi B, Mehta SK. Rectosigmoid varices and other mucosal changes in patients with portal hypertension. Am J Gastroenterol. 1991;86:1185–9.
4.
5.
go back to reference Sun WM, Peck RJ, Shorthouse AJ, Read NW. Haemorrhoids are associated not with hypertrophy of the internal anal sphincter, but with hypertension of the anal cushions. Br J Surg. 1992;79:592–4.CrossRef Sun WM, Peck RJ, Shorthouse AJ, Read NW. Haemorrhoids are associated not with hypertrophy of the internal anal sphincter, but with hypertension of the anal cushions. Br J Surg. 1992;79:592–4.CrossRef
6.
go back to reference Ho YH, Seow-Choen F, Goh HS. Haemorrhoidectomy and disordered rectal and anal physiology in patients with prolapsed haemorrhoids. Br J Surg. 1995;82:596–8.CrossRef Ho YH, Seow-Choen F, Goh HS. Haemorrhoidectomy and disordered rectal and anal physiology in patients with prolapsed haemorrhoids. Br J Surg. 1995;82:596–8.CrossRef
7.
go back to reference Aigner F, Gruber H, Conrad F, Eder J, Wedel T, Zelger B, Engelhardt V, Lametschwandtner A, Wienert V, Böhler U, Margreiter R, Fritsch H. Revised morphology and hemodynamics of the anorectal vascular plexus: impact on the course of hemorrhoidal disease. Int J Colorectal Dis. 2009;24:105–13.CrossRef Aigner F, Gruber H, Conrad F, Eder J, Wedel T, Zelger B, Engelhardt V, Lametschwandtner A, Wienert V, Böhler U, Margreiter R, Fritsch H. Revised morphology and hemodynamics of the anorectal vascular plexus: impact on the course of hemorrhoidal disease. Int J Colorectal Dis. 2009;24:105–13.CrossRef
8.
go back to reference American Gastroenterological Association medical position statement. Diagnosis and treatment of hemorrhoids. Gastroenterology. 2004;126:1461–2. American Gastroenterological Association medical position statement. Diagnosis and treatment of hemorrhoids. Gastroenterology. 2004;126:1461–2.
9.
go back to reference Goligher JC. Haemorrhoids or piles. In: Goligher JC, Duthie HL, Nixon HH, editors. Surgery of the anus, rectum and colon. 4th ed. London: Baillière Tindall; 1980. p. 96. Goligher JC. Haemorrhoids or piles. In: Goligher JC, Duthie HL, Nixon HH, editors. Surgery of the anus, rectum and colon. 4th ed. London: Baillière Tindall; 1980. p. 96.
10.
go back to reference Gallo G, Martellucci J, Sturiale A, Clerico G, Milito G, Marino F, Cocorullo G, Giordano P, Mistrangelo M, Trompetto M. Consensus statement of the Italian society of colorectal surgery (SICCR): management and treatment of hemorrhoidal disease. Tech Coloproctol. 2020;24(2):145–64. https://doi.org/10.1007/s10151-020-02149-1.CrossRef Gallo G, Martellucci J, Sturiale A, Clerico G, Milito G, Marino F, Cocorullo G, Giordano P, Mistrangelo M, Trompetto M. Consensus statement of the Italian society of colorectal surgery (SICCR): management and treatment of hemorrhoidal disease. Tech Coloproctol. 2020;24(2):145–64. https://​doi.​org/​10.​1007/​s10151-020-02149-1.CrossRef
12.
go back to reference Gallo G, Pietroletti R, Novelli E, Sturiale A, Tutino R, Lobascio P, Laforgia R, Moggia E, Pozzo M, Roveroni M, Bianco V, Luc AR, Giuliani A, Diaco E, Naldini G, Trompetto M, Perinotti R, Sammarco G. A multicentre, open-label, single-arm phase II trial of the efficacy and safety of sclerotherapy using 3% polidocanol foam to treat second-degree haemorrhoids (SCLEROFOAM). Tech Coloproctol. 2022;26(8):627–36. https://doi.org/10.1007/s10151-022-02609-w.CrossRef Gallo G, Pietroletti R, Novelli E, Sturiale A, Tutino R, Lobascio P, Laforgia R, Moggia E, Pozzo M, Roveroni M, Bianco V, Luc AR, Giuliani A, Diaco E, Naldini G, Trompetto M, Perinotti R, Sammarco G. A multicentre, open-label, single-arm phase II trial of the efficacy and safety of sclerotherapy using 3% polidocanol foam to treat second-degree haemorrhoids (SCLEROFOAM). Tech Coloproctol. 2022;26(8):627–36. https://​doi.​org/​10.​1007/​s10151-022-02609-w.CrossRef
14.
go back to reference Similis C, Thoukididou SN, Slesser AA, Rasheed S, Tan E, Tekkis PP. Systematic review and network meta-analysis comparing clinical outcomes and effectiveness of surfigal treatment for haemorrhoids. Br J Surg. 2015;102:1603–18.CrossRef Similis C, Thoukididou SN, Slesser AA, Rasheed S, Tan E, Tekkis PP. Systematic review and network meta-analysis comparing clinical outcomes and effectiveness of surfigal treatment for haemorrhoids. Br J Surg. 2015;102:1603–18.CrossRef
16.
go back to reference Ram E, Bachan GR, Goldes Y, Joubran S, Rath-Wolfson L. Modified Doppler-guided laser procedure for the treatment of sec-ond- and third-degree hemorrhoids. Laser Ther. 2018;27:137–42.CrossRef Ram E, Bachan GR, Goldes Y, Joubran S, Rath-Wolfson L. Modified Doppler-guided laser procedure for the treatment of sec-ond- and third-degree hemorrhoids. Laser Ther. 2018;27:137–42.CrossRef
19.
go back to reference Hoyuela C, Carvajal F, Juvany M, Troyano D, Trias M, Martrat A, Ardid J, Obiols J. HAL-RAR (Doppler guided haemorrhoid artery ligation with recto-anal repair) is a safe and effective procedure for haemorrhoids. Results of a prospective study after two-years follow-up. Int J Surg. 2016;28:39–44. https://doi.org/10.1016/j.ijsu.2016.02.030.CrossRef Hoyuela C, Carvajal F, Juvany M, Troyano D, Trias M, Martrat A, Ardid J, Obiols J. HAL-RAR (Doppler guided haemorrhoid artery ligation with recto-anal repair) is a safe and effective procedure for haemorrhoids. Results of a prospective study after two-years follow-up. Int J Surg. 2016;28:39–44. https://​doi.​org/​10.​1016/​j.​ijsu.​2016.​02.​030.CrossRef
20.
go back to reference Milligan ETC, Morgan CN. Surgical anatomy of the anal canal andoperative treatment of haemorrhoids. Lancet. 1937;2:1119–24.CrossRef Milligan ETC, Morgan CN. Surgical anatomy of the anal canal andoperative treatment of haemorrhoids. Lancet. 1937;2:1119–24.CrossRef
21.
go back to reference Altomare DF, Roveran A, Pecorella G, Gaj F, Stortini E. The treatment of hemorrhoids: guidelines of the Italian Society of Colorectal Surgery. Tech Coloproctol. 2006;10(3):181–6.CrossRef Altomare DF, Roveran A, Pecorella G, Gaj F, Stortini E. The treatment of hemorrhoids: guidelines of the Italian Society of Colorectal Surgery. Tech Coloproctol. 2006;10(3):181–6.CrossRef
22.
go back to reference Sobrado Júnior CW, de Almeida Obregon C, da Silva e Sousa Júnior AH, Sobrado LF, Nahas SC, Cecconello I. A new classification for hemorrhoidal disease: the creation of the “BPRST” staging and its application in clinical practice. Ann Coloproctol. 2020;36(4):249–55.CrossRef Sobrado Júnior CW, de Almeida Obregon C, da Silva e Sousa Júnior AH, Sobrado LF, Nahas SC, Cecconello I. A new classification for hemorrhoidal disease: the creation of the “BPRST” staging and its application in clinical practice. Ann Coloproctol. 2020;36(4):249–55.CrossRef
23.
go back to reference Rubbini M, Ascanelli S. Classification and guidelines of hemorrhoidal disease: present and future. World J Gastrointest Surg. 2019;11(3):117–21.CrossRef Rubbini M, Ascanelli S. Classification and guidelines of hemorrhoidal disease: present and future. World J Gastrointest Surg. 2019;11(3):117–21.CrossRef
26.
go back to reference Carvajal López F, Hoyuela Alonso C, Juvany Gómez M, Troyano Escribano D, Trias Bisbal MA, Martrat Macià A, Ardid BJ. Prospective randomized trial comparing HAL-RAR versus excisional hemorrhoidectomy: postoperative pain, clinical outcomes, and quality of life. Surg Innov. 2019;26(3):328–36. https://doi.org/10.1177/1553350618822644.CrossRef Carvajal López F, Hoyuela Alonso C, Juvany Gómez M, Troyano Escribano D, Trias Bisbal MA, Martrat Macià A, Ardid BJ. Prospective randomized trial comparing HAL-RAR versus excisional hemorrhoidectomy: postoperative pain, clinical outcomes, and quality of life. Surg Innov. 2019;26(3):328–36. https://​doi.​org/​10.​1177/​1553350618822644​.CrossRef
27.
go back to reference Brown SR, Tiernan JP, Watson AJM, Biggs K, Shephard N, Wailoo AJ, Bradburn M, Alshreef A, Hind D, HubBLe Study team. Haemorrhoidal artery ligation versus rubber band ligation for the management of symptomatic second-degree and third-degree haemorrhoids (HubBLe): a multicentre, open-label, randomised controlled trial. Lancet. 2016;388(10042):356–64. https://doi.org/10.1016/S0140-6736(16)30584-0.CrossRef Brown SR, Tiernan JP, Watson AJM, Biggs K, Shephard N, Wailoo AJ, Bradburn M, Alshreef A, Hind D, HubBLe Study team. Haemorrhoidal artery ligation versus rubber band ligation for the management of symptomatic second-degree and third-degree haemorrhoids (HubBLe): a multicentre, open-label, randomised controlled trial. Lancet. 2016;388(10042):356–64. https://​doi.​org/​10.​1016/​S0140-6736(16)30584-0.CrossRef
Metadata
Title
Milligan–Morgan hemorrhoidectomy vs. hemorrhoid artery ligation and recto-anal repair: a comparative study
Authors
Dimitrios Symeonidis
Michail Spyridakis
Dimitrios Zacharoulis
George Tzovaras
Athina A. Samara
Alexandros Valaroutsos
Alexandros Diamantis
Konstantinos Tepetes
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Surgery / Issue 1/2022
Electronic ISSN: 1471-2482
DOI
https://doi.org/10.1186/s12893-022-01861-z

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