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Techniques in Coloproctology
Published in: Techniques in Coloproctology 3/2010

01-09-2010 | Case Report

Mifepristone (RU486), a pure antiprogesterone drug, in combination with vinblastine for the treatment of progesterone receptor-positive desmoid tumor

Authors: A. Halevy, I. Samuk, Z. Halpern, L. Copel, J. Sandbank, Y. Ziv

Published in: Techniques in Coloproctology | Issue 3/2010

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Abstract

We report the case of a patient who developed a desmoid tumor following total proctocolectomy and J-pouch reconstruction that was unresponsive to any medical treatment. Based on estrogen receptor alpha (ERα) and progesterone receptor (PR) evaluation (ERα-negative, but PR-positive), treatment with mifepristone, a pure antiprogesterone drug, was initiated, and partial tumor regression was achieved.
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Metadata
Title
Mifepristone (RU486), a pure antiprogesterone drug, in combination with vinblastine for the treatment of progesterone receptor-positive desmoid tumor
Authors
A. Halevy
I. Samuk
Z. Halpern
L. Copel
J. Sandbank
Y. Ziv
Publication date
01-09-2010
Publisher
Springer Milan
Published in
Techniques in Coloproctology / Issue 3/2010
Print ISSN: 1123-6337
Electronic ISSN: 1128-045X
DOI
https://doi.org/10.1007/s10151-010-0591-2

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