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Open Access 01-12-2013 | Letters to the Editor

Midterm results after treatment of gram-positive deep sternal wound infections with daptomycin for cardiac surgery patients

Authors: Katharina R Ort, Fawad A Jebran, Christian Bireta, Bernhard C Danner, Ioannis Bougioukas, Friedrich A Schoendube, Aron F Popov

Published in: Journal of Cardiothoracic Surgery | Issue 1/2013

Abstract

Daptomycin in combination with surgical therapy has shown to be effective for treatment of deep sternal wound infection in cardiac surgery. However, till now midterm results in terms of re-infection or re-operation in patients who were successfully treated with daptomycin for gram-positive deep sternal wound infection are not published. Herein, we present midterm results in patients treated successfully with daptomycin after cardiac surgery.

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Popov AF, Schmitto JD, Jebran AF, Bireta C, Friedrich M, Rajaruthnam D, Coskun KO, Braeuer A, Hinz J, Tirilomis T, Schoendube FA: Treatment of gram-positive deep sternal wound infections in cardiac surgery–experiences with daptomycin. J Cardiothorac Surg. 2011, 6: 112-10.1186/1749-8090-6-112.CrossRefPubMedPubMedCentral

Sjogren J, Malmsjo M, Gustafsson R, Ingemansson R: Poststernotomy mediastinitis: a review of conventional surgical treatments, vacuum assisted closure therapy and presentation of the Lund University Hospital mediastinitis algorithm. Eur J Cardiothorac Surg. 2006, 30: 898-905. 10.1016/j.ejcts.2006.09.020.CrossRefPubMed

Popov AF, Schmitto JD, Tirilomis T, Bireta C, Coskun KO, Mokashi SA, Emmert A, Friedrich M, Wiese CH, Schoendube FA: Daptomycin as a possible new treatment option for surgical management of Methicillin-Resistant Staphylococcus aureus sternal wound infection after cardiac surgery. J Cardiothorac Surg. 2010, 5: 57-PubMedPubMedCentral

Weis F, Heyn J, Hinske CL, Vogt F, Weis M, Kur F, Hagl C, Beiras-Fernandez A: Daptomycin as supportive treatment option in patients developing mediastinitis after open cardiac surgery. J Cardiothorac Surg. 2012, 7 (1): 81-10.1186/1749-8090-7-81.CrossRefPubMedPubMedCentral

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Title: Midterm results after treatment of gram-positive deep sternal wound infections with daptomycin for cardiac surgery patients
Authors: Katharina R Ort
Fawad A Jebran
Christian Bireta
Bernhard C Danner
Ioannis Bougioukas
Friedrich A Schoendube
Aron F Popov
Publication date: 01-12-2013
Publisher: BioMed Central
Published in: Journal of Cardiothoracic Surgery / Issue 1/2013
Electronic ISSN: 1749-8090
DOI: https://doi.org/10.1186/1749-8090-8-21

At a glance: The STEP trials

Springer Medicine

Midterm results after treatment of gram-positive deep sternal wound infections with daptomycin for cardiac surgery patients

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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