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Cancer Cell International
Published in: Cancer Cell International 1/2015

Open Access 01-12-2015 | Review

MicroRNA-7: a promising new target in cancer therapy

Authors: Juanjuan Zhao, Yijing Tao, Ya Zhou, Nalin Qin, Chao Chen, Dan Tian, Lin Xu

Published in: Cancer Cell International | Issue 1/2015

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Abstract

The incidence of tumors with life-threatening effects has increased gradually over time; however, the mechanisms involved in tumor development have not been fully elucidated. Recent studies have shown that microRNA-7 (miR-7), which is endogenous non-coding RNA molecules of approximately 23 nucleotides, plays an important role in the occurrence and development of tumors as a key tumor suppressor. Mechanistic evidence showed that miR-7 is closely related to the growth, metastasis, and prognosis of various malignant tumors through regulating different target molecules, which suggest that miR-7 may be a new target for the clinical diagnosis and treatment of various tumors. In this review, we summarize current knowledge of the relationship between miR-7 and tumor development, diagnosis, and treatment.
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Metadata
Title
MicroRNA-7: a promising new target in cancer therapy
Authors
Juanjuan Zhao
Yijing Tao
Ya Zhou
Nalin Qin
Chao Chen
Dan Tian
Lin Xu
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Cancer Cell International / Issue 1/2015
Electronic ISSN: 1475-2867
DOI
https://doi.org/10.1186/s12935-015-0259-0

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