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Open Access 01-04-2014 | Poster presentation

Mice survival in a two-hit model of sepsis depends on intratracheal P. aeruginosa bacterial load

Authors: D Restagno, J-M Bonnet, A Kodjo, F Venet, C Paquet, L Freyburger, V Louzier

Published in: Critical Care | Special Issue 2/2014

Excerpt

Sepsis is a systemic reaction in the presence of an infection characterized by an early systemic inflammatory response syndrome followed by a compensatory anti-inflammatory response syndrome. The first side of this typical immune response is responsible for widespread damage organ whereas the second part leads to an immunoparalysis increasing patients' susceptibility to secondary infections. The goal of this study is to finalize a murine model of sepsis to understand the physiopathology of sepsis and eventually test new therapeutic approaches. …

Title: Mice survival in a two-hit model of sepsis depends on intratracheal P. aeruginosa bacterial load
Authors: D Restagno
J-M Bonnet
A Kodjo
F Venet
C Paquet
L Freyburger
V Louzier
Publication date: 01-04-2014
Publisher: BioMed Central
Published in: Critical Care / Issue Special Issue 2/2014
Electronic ISSN: 1364-8535
DOI: https://doi.org/10.1186/cc14062

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Mice survival in a two-hit model of sepsis depends on intratracheal P. aeruginosa bacterial load

Excerpt

Keynote webinar | Spotlight on medication adherence

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