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BMC Ophthalmology

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Open Access 01-12-2017 | Case report

Metastatic retinoblastoma of the parotid and submandibular glands: a rare case report

Authors: Ping Wang, Yang-Jun Li, Shao-Bo Zhang, Qi-Lin Cheng, Qiong Zhang, Li-Sha He

Published in: BMC Ophthalmology | Issue 1/2017

Abstract

Background

Retinoblastoma is the most common intraocular malignancy occurring in children. It can metastasize to the regional lymph nodes, central nervous system and distant organs usually the bones and bone marrow and very rarely to the soft tissue. Here, we report a case of unilateral retinoblastoma in a 4-year-old girl accompanied by a large metastasis of the parotid and submandibular glands that developed about 6 months previously and gradually increased in size 5 months after enucleation of the left eye.

Case presentation

A 4-year-old girl with a history of unilateral retinoblastoma presented with a large, painful and worsening mass (about 20 × 23 cm) of the left side of the neck. Following surgery, the orbital tumour was completely resected, and the large tumour invasion range in the left side of the neck was not resected completely. Histopathological examination revealed retinoblastoma of the orbit and the parotid and submandibular glands. After chemotherapy and additional local radiotherapy on the parotid and submandibular glands, the tumour was inactive and stable.

Conclusions

Delayed detection and inappropriate management contribute to poor outcomes. Fundus examinations, education regarding the early signs of RB, and optimization of the therapeutic strategy for RB may play important roles in ocular health.

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Title: Metastatic retinoblastoma of the parotid and submandibular glands: a rare case report
Authors: Ping Wang
Yang-Jun Li
Shao-Bo Zhang
Qi-Lin Cheng
Qiong Zhang
Li-Sha He
Publication date: 01-12-2017
Publisher: BioMed Central
Published in: BMC Ophthalmology / Issue 1/2017
Electronic ISSN: 1471-2415
DOI: https://doi.org/10.1186/s12886-017-0627-8

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Metastatic retinoblastoma of the parotid and submandibular glands: a rare case report

Abstract

Background

Case presentation

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Case presentation

Conclusions

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