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Child's Nervous System
Published in: Child's Nervous System 9/2009

01-09-2009 | Case Report

Metastatic craniopharyngioma: case report and literature review

Authors: Evan Mark Frangou, Jennifer Ruth Tynan, Christopher Adam Robinson, Lissa Marie Ogieglo, Aleksander Michal Vitali

Published in: Child's Nervous System | Issue 9/2009

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Abstract

Background

Distant spread of craniopharyngioma is a rare but important complication. Most cases are a result of spread along the surgical path. We describe a rare case of metastatic leptomeningeal craniopharyngioma as a result of dissemination along CSF pathways in a child. A review of previously described cases is provided.

Case presentation

A 14-year-old male was diagnosed with metastatic craniopharyngioma on routine follow-up imaging after multiple surgeries and radiation for locally recurrent craniopharyngioma. The lesion was erosive through the right parietal bone, but had remained clinically silent. The lesion was distant from previous surgical paths. The patient underwent right parietal craniotomy and resection of the lesion. Duraplasty and cranioplasty were necessary for closure. Histopathology confirmed adamantinomatous craniopharyngioma. One-year follow-up demonstrated no recurrence.

Discussion

A review of reported cases suggests that leptomeningeal implantation may be an important step in metastases of craniopharyngioma, although the mechanism is poorly understood. Attention to tumor spillage at the time of surgery may be important in preventing distant recurrences.
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Metadata
Title
Metastatic craniopharyngioma: case report and literature review
Authors
Evan Mark Frangou
Jennifer Ruth Tynan
Christopher Adam Robinson
Lissa Marie Ogieglo
Aleksander Michal Vitali
Publication date
01-09-2009
Publisher
Springer-Verlag
Published in
Child's Nervous System / Issue 9/2009
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-009-0917-4

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