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Journal of Medical Case Reports
Published in: Journal of Medical Case Reports 1/2020

01-12-2020 | Metastasis | Case report

Giant paratesticular liposarcoma with lung metastases: a case report and review of the literature

Authors: Takuro Noguchi, Toshirou Fukushima, Hiroaki Hara, Nodoka Sekiguchi, Takashi Kobayashi, Takesumi Ozawa, Daisuke Gomi, Tomonobu Koizumi

Published in: Journal of Medical Case Reports | Issue 1/2020

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Abstract

Background

Due to its rarity, little is known about the clinical presentations and responses to systemic chemotherapies in advanced and/or metastatic cases of paratesticular liposarcoma.

Case presentation

Here, we report the case of a 75-year-old Japanese man with giant paratesticular liposarcoma. Imaging studies revealed a 26 cm tumor in his right scrotum and lung metastases at presentation. He underwent radical orchiectomy followed by systemic chemotherapies. Pathological findings of the resected primary tumor confirmed a dedifferentiated liposarcoma. He then started chemotherapy treatment with gemcitabine plus docetaxel. His disease status was stable for 1 year. Eribulin was used for second-line chemotherapy. He had a relapse at 5 months after eliburin and died at 22 months after diagnosis.

Conclusion

Early diagnosis and curative radical surgery are important for treatment of paratesticular liposarcoma. However, a giant paratesticular liposarcoma could cause metastases, and systemic chemotherapy may be helpful for prolonging survival in patients with metastatic paratesticular liposarcoma.
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Metadata
Title
Giant paratesticular liposarcoma with lung metastases: a case report and review of the literature
Authors
Takuro Noguchi
Toshirou Fukushima
Hiroaki Hara
Nodoka Sekiguchi
Takashi Kobayashi
Takesumi Ozawa
Daisuke Gomi
Tomonobu Koizumi
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2020
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/s13256-020-02420-x

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