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Published in: General Thoracic and Cardiovascular Surgery 10/2022

11-08-2022 | Metastasis | How to Do It

Optimal settings of near-infrared fluorescence imaging with indocyanine green for intraoperative detection of lymph node metastasis in esophageal cancer

Authors: Ryohei Iwata, Shinichiro Shiomi, Susumu Aikou, Koichi Yagi, Hiroharu Yamashita, Yasuyuki Seto

Published in: General Thoracic and Cardiovascular Surgery | Issue 10/2022

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Abstract

Lymphatic flow mapping using near-infrared fluorescence (NIR) imaging with indocyanine green (ICG) has been used for intraoperative diagnosis of lymph node metastasis (LNM) in various cancers. Accurate prediction of LNM intraoperatively may allow minimization of the extent of lymphadenectomy. However, a consistent method and diagnostic ability, allowing application of NIR-guided lymphatic flow mapping to esophageal cancer (EC), have not been established due to the multidirectional and complex characteristics of lymphatic flow in the esophagus. Herein, we present a novel NIR-guided surgical technique for predicting lymph node stations potentially containing LNM in EC with high diagnostic accuracy derived from appropriately adjusting the ICG injection setting.
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Metadata
Title
Optimal settings of near-infrared fluorescence imaging with indocyanine green for intraoperative detection of lymph node metastasis in esophageal cancer
Authors
Ryohei Iwata
Shinichiro Shiomi
Susumu Aikou
Koichi Yagi
Hiroharu Yamashita
Yasuyuki Seto
Publication date
11-08-2022
Publisher
Springer Nature Singapore
Published in
General Thoracic and Cardiovascular Surgery / Issue 10/2022
Print ISSN: 1863-6705
Electronic ISSN: 1863-6713
DOI
https://doi.org/10.1007/s11748-022-01859-7

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