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Annals of Surgical Oncology
Published in: Annals of Surgical Oncology 3/2021

01-03-2021 | Metastasis | ASO Author Reflections

ASO Author Reflections: Lymph Node Metastasis of Esophageal Cancer After Trimodal Therapy

Author: Yoichi Hamai, MD, PhD

Published in: Annals of Surgical Oncology | Issue 3/2021

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Excerpt

The frequency of lymph node metastasis (LNM) is high in the early stages of esophageal cancer. Thus, pathological LNM is prevalent in patients with locally advanced esophageal cancer, even after neoadjuvant chemoradiotherapy (NCRT) followed by surgery. Pathological LNM is closely associated with prognosis after trimodal therapy.1‐4 Although NCRT would arguably affect metastatic tumors in LNs, the distribution of LNM of esophageal squamous cell carcinoma (ESCC) after trimodal therapy has never been absolutely determined. …
Literature
1.
Hamai Y, Hihara J, Emi M, et al. Evaluation of prognostic factors for esophageal squamous cell carcinoma treated with neoadjuvant chemoradiotherapy followed by surgery. World J Surg. 2018;42:1496–1505.CrossRef
2.
Hamai Y, Emi M, Ibuki Y, et al. Early recurrence and cancer death after trimodal therapy for esophageal squamous cell carcinoma. Anticancer Res. 2019;39:1433–1440.CrossRef
3.
Hamai Y, Hihara J, Emi M, et al. Clinical significance of 18F-Fluorodeoxyglucose-positron emission tomography-positive lymph nodes to outcomes of trimodal therapy for esophageal squamous cell carcinoma. Ann Surg Oncol. 2019;26:1869–1878.CrossRef
4.
Kurokawa T, Hamai Y, Emi M, et al. Risk factors for recurrence in esophageal squamous cell carcinoma without pathological complete response after trimodal Therapy. Anticancer Res. 2020;40:4387–4394. CrossRef
5.
Metadata
Title
ASO Author Reflections: Lymph Node Metastasis of Esophageal Cancer After Trimodal Therapy
Author
Yoichi Hamai, MD, PhD
Publication date
01-03-2021
Publisher
Springer International Publishing
Published in
Annals of Surgical Oncology / Issue 3/2021
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-020-09121-1

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