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BMC Psychiatry

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Open Access 01-12-2020 | Research article

Metabolic syndrome associated with the onset of depressive symptoms among women but not men in rural Northeast China

Authors: Shasha Yu, Xiaofan Guo, Guang Xiao Li, Hongmei Yang, Liqiang Zheng, Yingxian Sun

Published in: BMC Psychiatry | Issue 1/2020

Abstract

Background

The present study aimed to assess the cumulative incidence of major depressive disorder (MDD) among rural Chinese residents. Furthermore, we intended to estimate whether metabolic syndrome (MetS) was associated with MDD by both cross-sectional and prospective analysis.

Method

Data of 11,675 residents (46.3% men) was used for cross-sectional analysis. The residents were followed up with median 4.66 years. MDD was diagnosed using the Patient Health Questionnaire-9 (PHQ-9). The data of 2796 individuals without any depressive symptoms was used for prospective analysis.

Result

With median of 4.66 years follow-up, the cumulative incidence of MDD among rural residents was 3.9%. Women had significantly higher cumulative incidence of MDD than men (5.3% for women and 2.9% for men, P < 0.01). The incidence of MDD was significantly higher among women with MetS (7.3% vs. 3.8%, P < 0.001), hypertriglyceridemia (7.0% vs. 4.5%, P < 0.001) or elevated blood pressure (6.4% vs. 3.4%, P < 0.001) at baseline compared with those without them. There was no incidence difference of MDD among men with or without baseline metabolic disorders. In prospective study, after adjusting possible confounders, baseline MetS was associated with higher incidence of MDD (OR: 1.82, 95%CI: 1.01, 3.27, P = 0.045) in women but not men (OR: 1.84, 95%CI: 0.88, 3.83, P = 0.104).

Conclusion

Cumulative incidence of MDD in rural China was higher among women than among men. Baseline MetS was associated with higher cumulative incidence of MDD in women but not men. More concern should be put on women with MetS in case of onset depressive symptom in future.

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Title: Metabolic syndrome associated with the onset of depressive symptoms among women but not men in rural Northeast China
Authors: Shasha Yu
Xiaofan Guo
Guang Xiao Li
Hongmei Yang
Liqiang Zheng
Yingxian Sun
Publication date: 01-12-2020
Publisher: BioMed Central
Published in: BMC Psychiatry / Issue 1/2020
Electronic ISSN: 1471-244X
DOI: https://doi.org/10.1186/s12888-020-02668-z

2024 ASCO Annual Meeting

Springer Medicine

Metabolic syndrome associated with the onset of depressive symptoms among women but not men in rural Northeast China

Abstract

Background

Method

Result

Conclusion

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Background

Method

Result

Conclusion

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