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Acta Neurochirurgica

Published in:

01-12-2024 | Meningioma | Original Article

Customised pre-operative cranioplasty to achieve maximal surgical resection of tumours with osseous involvement—a case series

Authors: Swati Jain, Adel Helmy, Thomas Santarius, Nicola Owen, Kirsty Grieve, Peter Hutchinson, Ivan Timofeev

Published in: Acta Neurochirurgica | Issue 1/2024

Abstract

Purpose

Surgical resection with bony margins would be the treatment of choice for tumours with osseous involvement such as meningiomas and metastasis. By developing and designing pre-operative customised 3D modelled implants, the patient can undergo resection of meningioma and repair of bone defect in the same operation. We present a generalisable method for designing pre-operative cranioplasty in patients to repair the bone defect after the resection of tumours.

Materials and methods

We included six patients who presented with a tumour that was associated with overlying bone involvement. They underwent placement of customised cranioplasty in the same setting. A customised implant using a pre-operative imaging was designed with a 2-cm margin to allow for any intra-operative requirements for extending the craniectomy.

Results

Six patients were evaluated in this case series. Four patients had meningiomas, 1 patient had metastatic breast cancer on final histology, and 1 patient was found to have an intra-osseous arteriovenous malformation. Craniectomy based on margins provided by a cutting guide was fashioned. After tumour removal and haemostasis, the cranioplasty was then placed. All patients recovered well post-operatively with satisfactory cosmetic results. No wound infection was reported in our series.

Conclusion

Our series demonstrate the feasibility of utilising pre-designed cranioplasty for meningiomas and other tumours with osseous involvement. Following strict infection protocols, minimal intra-operative handling/modification of the implant, and close follow-up has resulted in good cosmetic outcomes with no implant-related infections.

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Title: Customised pre-operative cranioplasty to achieve maximal surgical resection of tumours with osseous involvement—a case series
Authors: Swati Jain
Adel Helmy
Thomas Santarius
Nicola Owen
Kirsty Grieve
Peter Hutchinson
Ivan Timofeev
Publication date: 01-12-2024
Publisher: Springer Vienna
Keywords: Meningioma
Meningioma
Bone Defect
Published in: Acta Neurochirurgica / Issue 1/2024
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI: https://doi.org/10.1007/s00701-024-06055-5

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Customised pre-operative cranioplasty to achieve maximal surgical resection of tumours with osseous involvement—a case series

Abstract

Purpose

Materials and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Materials and methods

Results

Conclusion

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