Top

Journal of Medical Case Reports

Published in:

Open Access 01-12-2009 | Case report

Medullary sponge kidney presenting in a neonate with distal renal tubular acidosis and failure to thrive: a case report

Authors: Mohamed El-Sawi, Abdul-Rahman Shahein

Published in: Journal of Medical Case Reports | Issue 1/2009

Abstract

Introduction

Medullary sponge kidney is a congenital anomaly characterized by diffuse ectasy of the collecting tubules of one or both kidneys. It is usually diagnosed in the second or third decade of life.

Case presentation

Distal renal tubular acidosis is commonly observed in patients with medullary sponge kidney. We describe here a 50-day-old Egyptian Caucasian girl with medullary sponge kidney who had features of distal renal tubular acidosis, (persistent alkaline urine, hypercalciuria, hypocitraturia) and failure to thrive. Renal ultrasound revealed left renal increased medullary echogenicity and bilateral nephrocalcinosis.

Conclusion

Early gene(s) expression of medullary sponge kidney disease might be responsible for persistent metabolic acidosis during the neonatal period.

Davidson AA, Cameron JS, Grunfield JP, Kerr DNS, Ritz E, Winearls CG: Oxford Textbook of Clinical Nephrology. Edited by: Cameron JS. 1998, Oxford University Press, 2565-2569. 2

Hildebrandit F, Jungers P, Grunfield JP: Diseases of the Kidney. Edited by: Schrier RWGottschalk CW. 1997, Little Brown, 1: 499-522. 6

Lalli AF: Medullary sponge kidney disease. Radiology. 1969, 92: 92-96.CrossRefPubMed

Toyoda K, Miyamoto Y, Ida M, Tada S, Utsunomiya M: Hyperechoic medulla of the kidneys. Radiology. 1989, 173: 431-434.CrossRefPubMed

Mcllwaine CL, Jalan KN: Hyperparathyroidism associated with medullary sponge kidney. Br J Urol. 1968, 40: 202-206. 10.1111/j.1464-410X.1968.tb09875.x.CrossRef

Ginalski JM, Portmann L, Jaeger P: Does medullary sponge kidney cause nephrolithiasis. AJR Am J Roentgenol. 1990, 155: 299-302.CrossRefPubMed

Sluysmans T, Vanoverschelde JP, Malvaux P: Growth failure associated with medullary sponge kidney, due to incomplete renal tubular acidosis type 1. Eur J Pediatr. 1987, 146: 78-80. 10.1007/BF00647294.CrossRefPubMed

Belde K, Alper S, Oğuz Ô, Mehmet T, Salih K: Sponge kidney associated with distal renal tubular acidosis in a 5-year-old girl. Eur J Pediatr. 2006, 165: 648-651. 10.1007/s00431-006-0125-0.CrossRef

Denis R, Yves P: Medullary sponge kidney-part of congenital syndrome. Nephrol Dial Transplant. 2001, 16: 634-636. 10.1093/ndt/16.3.634.CrossRef

10.

Pesce C, Colombo B, Nicolini E, Spata F, Cappellari F: Medullary sponge kidney with severe renal function impairment: a case report. Pediatr Med Chir. 1995, 17: 65-67.PubMed

11.

Abeshouse BS, Abeshouse GA: Sponge kidney: a review of the literature and a report of five cases. J Urol. 1960, 84: 252-267.PubMed

12.

Patriquin HB, O'Regan S: Medullary sponge kidney in childhood. AJR Am J Roentgenol. 1985, 145: 315-319.CrossRefPubMed

Title: Medullary sponge kidney presenting in a neonate with distal renal tubular acidosis and failure to thrive: a case report
Authors: Mohamed El-Sawi
Abdul-Rahman Shahein
Publication date: 01-12-2009
Publisher: BioMed Central
Published in: Journal of Medical Case Reports / Issue 1/2009
Electronic ISSN: 1752-1947
DOI: https://doi.org/10.1186/1752-1947-3-6656

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Medullary sponge kidney presenting in a neonate with distal renal tubular acidosis and failure to thrive: a case report

Abstract

Introduction

Case presentation

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Case presentation

Conclusion

Please log in to get access to this content

Other articles of this Issue 1/2009

A levonorgestrel-releasing intrauterine system embedded in the omentum in a woman with abdominal pain: a case report

Celiac disease as a potential cause of idiopathic portal hypertension: a case report

A rare case of neuroleptic malignant syndrome presenting with serious hyperthermia treated with a non-invasive cooling device: a case report

Episodic biliary obstruction due to an intrahepatic biliary cystadenoma: a case report

Complete abdominal aortic aneurysm thrombosis and obstruction of both common iliac arteries with intrathrombotic pressures demonstrating a continuing risk of rupture: a case report and review of the literature

Bilateral thalamic stroke due to occlusion of the artery of Percheron in a patient with patent foramen ovale: a case report