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01-11-2007 | Short Report

Medium-term survival without haematopoietic stem cell transplantation in a case of IPEX: insights into nutritional and immunosuppressive therapy

Authors: Andrea Taddio, Elena Faleschini, Erica Valencic, Marilena Granzotto, Alberto Tommasini, Loredana Lepore, Marino Andolina, Egidio Barbi, Alessandro Ventura

Published in: European Journal of Pediatrics | Issue 11/2007

Excerpt

Immunodysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX; OMIM 304930) is a severe disorder of immune development characterised by a usually fatal course in early childhood [6]. It is due to mutations in the FOXP3 gene (locus Xp11.23-q13.3) [2, 4, 9], leading to failure in immune tolerance. …

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Wildin RS, Smyk-Pearson S, Filipovich AH (2002) Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome. J Med Genet 39(8):537–545PubMedCrossRef

Title: Medium-term survival without haematopoietic stem cell transplantation in a case of IPEX: insights into nutritional and immunosuppressive therapy
Authors: Andrea Taddio
Elena Faleschini
Erica Valencic
Marilena Granzotto
Alberto Tommasini
Loredana Lepore
Marino Andolina
Egidio Barbi
Alessandro Ventura
Publication date: 01-11-2007
Publisher: Springer-Verlag
Published in: European Journal of Pediatrics / Issue 11/2007
Print ISSN: 0340-6199
Electronic ISSN: 1432-1076
DOI: https://doi.org/10.1007/s00431-006-0395-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Medium-term survival without haematopoietic stem cell transplantation in a case of IPEX: insights into nutritional and immunosuppressive therapy

Excerpt

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Excerpt

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