Skip to main content
Top
Published in: Current Allergy and Asthma Reports 6/2012

Open Access 01-12-2012 | Pediatric Allergy and Immunology (JM Portnoy and CE Ciaccio, Section Editors)

Medical Causation and Expert Testimony: Allergists at this Intersection of Medicine and Law

Authors: Howard M. Weiner, Ronald E. Gots, Robert P. Hein

Published in: Current Allergy and Asthma Reports | Issue 6/2012

Login to get access

Abstract

Clinical practice always necessitates proper diagnosis and correct treatment. For most clinical fields, determining the cause of the illness is irrelevant to the intervention. An oncologist, for example, has no need to explore the “cause” of the patient’s lymphoma. Allergists, by contrast, have tools and the need to examine the relevant allergen which is the putative “cause” of the patient’s allergic symptomatology. In the context of a legal claim, the “cause” of the symptoms or disorder is central, because it determines financial responsibility. However, in the case of an allergic disorder and identified allergen, a claim requires more. Whose allergen? Where did it come from? These are crucial questions that must be answered. This paper explores the approaches to causal assessment which are important for the clinical allergist as he/she navigates the interface between clinical practice and legal proceedings. Its purpose is to help the allergist understand that interface, and to be prepared to enter an unfamiliar legal arena.
Literature
1.
go back to reference Evans AS. Causation and disease: the Henle-Koch postulates revisited. Yale J Biol Med. 1976;49(2):175–95.PubMed Evans AS. Causation and disease: the Henle-Koch postulates revisited. Yale J Biol Med. 1976;49(2):175–95.PubMed
2.
go back to reference Hackney JD, Linn WS. Koch's postulates updated: a potentially useful application to laboratory research and policy analysis in environmental toxicology. Am Rev Respir Dis. 1979;119:849–52.PubMed Hackney JD, Linn WS. Koch's postulates updated: a potentially useful application to laboratory research and policy analysis in environmental toxicology. Am Rev Respir Dis. 1979;119:849–52.PubMed
3.
go back to reference Irey NS. Diagnostic problems in drug-induced diseases. Ann Clin Lab Sci. 1976;6:272–7.PubMed Irey NS. Diagnostic problems in drug-induced diseases. Ann Clin Lab Sci. 1976;6:272–7.PubMed
4.
go back to reference Irey NS, Mullick FG. Syllabus: environmental pathology. Washington, DC: Armed Forces Institute of Pathology; 1984. p. 1–50. Irey NS, Mullick FG. Syllabus: environmental pathology. Washington, DC: Armed Forces Institute of Pathology; 1984. p. 1–50.
5.
go back to reference Gots RE, Gots BA, Spencer J. Proving causes of illness in environmental toxicology: 'Sick buildings' as an example. Fresenius Environ Bull. 1992;1:135–42. Gots RE, Gots BA, Spencer J. Proving causes of illness in environmental toxicology: 'Sick buildings' as an example. Fresenius Environ Bull. 1992;1:135–42.
6.
7.
go back to reference Gots RE. Scientific and legal approaches to proof of causation in tort cases. 3rd Chemical Congress of North Am: the book of abstracts ACS. 1988;#16 CHAL. Gots RE. Scientific and legal approaches to proof of causation in tort cases. 3rd Chemical Congress of North Am: the book of abstracts ACS. 1988;#16 CHAL.
8.
go back to reference Gots RE. Toxic risks: science, regulation, and perception. Boca Raton: Lewis Publishers; 1993. Gots RE. Toxic risks: science, regulation, and perception. Boca Raton: Lewis Publishers; 1993.
9.
go back to reference Guzelian PS, et al. Evidence-based toxicology: a comprehensive framework for causation. Hum Exp Toxicol. 2005;24(4):161–201.PubMedCrossRef Guzelian PS, et al. Evidence-based toxicology: a comprehensive framework for causation. Hum Exp Toxicol. 2005;24(4):161–201.PubMedCrossRef
10.
go back to reference Hill AB. The environment and disease: association or causation? Proc R Soc Med. 1965;58:295–300.PubMed Hill AB. The environment and disease: association or causation? Proc R Soc Med. 1965;58:295–300.PubMed
11.
go back to reference Schwartz SL. An overall conceptual approach to the problem of causation. Shepard's Expert Sci Evid Q. 1995;3(1):1–24. Schwartz SL. An overall conceptual approach to the problem of causation. Shepard's Expert Sci Evid Q. 1995;3(1):1–24.
12.
go back to reference Klaassen CD. Toxicology: the basic science of poisons. 7th ed. New York: McGraw Hill Medical; 2008. Klaassen CD. Toxicology: the basic science of poisons. 7th ed. New York: McGraw Hill Medical; 2008.
13.
go back to reference Black B, Warshaw MS, Hollander DH. Unraveling causation: back to the basics. Toxics Law Reporter. 1993;1061-1070. Black B, Warshaw MS, Hollander DH. Unraveling causation: back to the basics. Toxics Law Reporter. 1993;1061-1070.
14.
go back to reference Muscat JE, Huncharek MS. Causation and disease: biomedical science in toxic tort litigation. J Occup Med. 1989;31:997–1002.PubMedCrossRef Muscat JE, Huncharek MS. Causation and disease: biomedical science in toxic tort litigation. J Occup Med. 1989;31:997–1002.PubMedCrossRef
15.
go back to reference Ruth JH. Odor Thresholds and Irritation Levels of several chemical substances: a review. Am Ind Hyg Assn J. 1986;47(3):A 142–51. Ruth JH. Odor Thresholds and Irritation Levels of several chemical substances: a review. Am Ind Hyg Assn J. 1986;47(3):A 142–51.
16.
go back to reference Documentation of Threshold Limit Values and Biological Exposure Indices, American Council of Governmental Industrial Hygienists (ACGIH), 1999. Documentation of Threshold Limit Values and Biological Exposure Indices, American Council of Governmental Industrial Hygienists (ACGIH), 1999.
17.
go back to reference Agency for Toxic Substances and Disease Registry (ATSDR), Toxicological Profiles (Sic. Various chemicals and years). Agency for Toxic Substances and Disease Registry (ATSDR), Toxicological Profiles (Sic. Various chemicals and years).
18.
go back to reference Richie IM, Lehnen RG. Formaldehyde-Related complaints of residents living in mobile and conventional homes. Am J Public Health. 1987;77:323–8.CrossRef Richie IM, Lehnen RG. Formaldehyde-Related complaints of residents living in mobile and conventional homes. Am J Public Health. 1987;77:323–8.CrossRef
19.
go back to reference Nielson GD, Alarie Y. Sensory irritation, pulmonary irritation, and respiratory stimulation by airborne benzene and alkylbenzenes: Prediction of safe inhdustrial exposure levels and correlation with their thermodynamic properties. Toxicol Appl Pharmacol. 1982;65(3):459–77.CrossRef Nielson GD, Alarie Y. Sensory irritation, pulmonary irritation, and respiratory stimulation by airborne benzene and alkylbenzenes: Prediction of safe inhdustrial exposure levels and correlation with their thermodynamic properties. Toxicol Appl Pharmacol. 1982;65(3):459–77.CrossRef
20.
go back to reference American College of Medical Toxicology Practice Committee, Sudakin DL and Kurt T American College of Medical Toxicology Position Statement on the Institute of Medicine Report on Damp Indoor Spaces and Health. 2006; October:1-4. American College of Medical Toxicology Practice Committee, Sudakin DL and Kurt T American College of Medical Toxicology Position Statement on the Institute of Medicine Report on Damp Indoor Spaces and Health. 2006; October:1-4.
21.
go back to reference American College of Occupational and Environmental Medicine Adverse human health effects associated with mold in the indoor environment. ACOEM Evidence-based statement: Position Statement/Guidelines:2002; 1-10. Web address: www.acoem.org American College of Occupational and Environmental Medicine Adverse human health effects associated with mold in the indoor environment. ACOEM Evidence-based statement: Position Statement/Guidelines:2002; 1-10. Web address: www.​acoem.​org
22.
go back to reference American College of Occupational and Environmental Medicine, ACOEM Council on Scientific Affairs, Hardin BD, Kelman BJ, Saxon A. Adverse human health effects associated with mold in the indoor environment Revised position statement. ACOEM. 2011; 1-7. 2-14. American College of Occupational and Environmental Medicine, ACOEM Council on Scientific Affairs, Hardin BD, Kelman BJ, Saxon A. Adverse human health effects associated with mold in the indoor environment Revised position statement. ACOEM. 2011; 1-7. 2-14.
23.
go back to reference Bush RK, et al. The medical effects of mold exposure: AAAAI Position Paper. J Allergy Clin Immunol. 2006;117(2):326–33.PubMedCrossRef Bush RK, et al. The medical effects of mold exposure: AAAAI Position Paper. J Allergy Clin Immunol. 2006;117(2):326–33.PubMedCrossRef
24.
go back to reference Fung F, Hughson WG. Health effects of indoor fungal bioaerosol exposure. Appl Occup Environ Hyg. 2003;18(7):535–44.PubMedCrossRef Fung F, Hughson WG. Health effects of indoor fungal bioaerosol exposure. Appl Occup Environ Hyg. 2003;18(7):535–44.PubMedCrossRef
25.
go back to reference Institute of Medicine (U.S.), Committee on Damp Indoor Spaces and Health, Board on Health Promotion and Disease Prevention of the Institutes of Medicine. Damp indoor spaces and health. Washington, DC: National Academies Press; 2004. Institute of Medicine (U.S.), Committee on Damp Indoor Spaces and Health, Board on Health Promotion and Disease Prevention of the Institutes of Medicine. Damp indoor spaces and health. Washington, DC: National Academies Press; 2004.
26.
go back to reference World Health Organization Guidelines for Indoor Air: Dampness and Mould. (2009) World Health Organization. Copenhagen, Denmark. World Health Organization Guidelines for Indoor Air: Dampness and Mould. (2009) World Health Organization. Copenhagen, Denmark.
28.
go back to reference Health Survey of the Population Living Near the Price Landfill, Egg Harbor Township, Atlantic County. (1983) Environmental Health Hazard Evaluation Program, New Jersey Department of Health, and DHEHHEP. Health Survey of the Population Living Near the Price Landfill, Egg Harbor Township, Atlantic County. (1983) Environmental Health Hazard Evaluation Program, New Jersey Department of Health, and DHEHHEP.
29.
go back to reference Kaye WE, Hall HI, Lybarger JA. Recall bias in disease status associated with perceived exposure to hazardous substances. Ann Epidemiol. 1994;4:393–7.PubMedCrossRef Kaye WE, Hall HI, Lybarger JA. Recall bias in disease status associated with perceived exposure to hazardous substances. Ann Epidemiol. 1994;4:393–7.PubMedCrossRef
30.
go back to reference Lees-Haley PR, Brown RS. Biases in perception and reporting following a perceived toxic exposure. Percept Mot Skills. 1992;75:531–44.PubMedCrossRef Lees-Haley PR, Brown RS. Biases in perception and reporting following a perceived toxic exposure. Percept Mot Skills. 1992;75:531–44.PubMedCrossRef
31.
go back to reference Lipscomb JA, Goldman LR, Satin KP, Smith DF, Vance WA, Neutra RR. A follow-up study of the community near the McColl waste disposal site. Environ Health Perspect. 1991;94:15–24.PubMedCrossRef Lipscomb JA, Goldman LR, Satin KP, Smith DF, Vance WA, Neutra RR. A follow-up study of the community near the McColl waste disposal site. Environ Health Perspect. 1991;94:15–24.PubMedCrossRef
32.
go back to reference Lipscomb JA, Satin KP, Neutra RR. Reported symptom prevalence rates from comparison populations in community-based environmental studies. Arch Environ Health. 1947;1002:263–9. Lipscomb JA, Satin KP, Neutra RR. Reported symptom prevalence rates from comparison populations in community-based environmental studies. Arch Environ Health. 1947;1002:263–9.
33.
go back to reference Logue JN, Fox JM. Residential health study of families living near the Drake Chemical Superfund site in Lock Haven, Pennsylvania. Arch Environ Health. 1096;41:222–8.CrossRef Logue JN, Fox JM. Residential health study of families living near the Drake Chemical Superfund site in Lock Haven, Pennsylvania. Arch Environ Health. 1096;41:222–8.CrossRef
34.
go back to reference Roht LH, Vernon SW, Weir FW, Pier SM, Sullivan P, Reed LJ. Community exposure to hazardous waste disposal sites: assessing reporting bias. Am J Epidemiol. 1985;122:418–33.PubMed Roht LH, Vernon SW, Weir FW, Pier SM, Sullivan P, Reed LJ. Community exposure to hazardous waste disposal sites: assessing reporting bias. Am J Epidemiol. 1985;122:418–33.PubMed
35.
go back to reference Pennebaker JW, Epstein D. Implicit psychophysiology: effects of common beliefs and idiosyncratic physiological responses on symptom reporting. J Pers. 1983;51:468–96.PubMedCrossRef Pennebaker JW, Epstein D. Implicit psychophysiology: effects of common beliefs and idiosyncratic physiological responses on symptom reporting. J Pers. 1983;51:468–96.PubMedCrossRef
36.
go back to reference Pennebaker JW. Psychological bases of symptom reporting: perceptual and emotional aspects of chemical sensitivity. Toxicol Ind Health. 1994;10:497–511.PubMed Pennebaker JW. Psychological bases of symptom reporting: perceptual and emotional aspects of chemical sensitivity. Toxicol Ind Health. 1994;10:497–511.PubMed
37.
go back to reference •• Berger MA. The Admissibility of expert testimony, reference manual on scientific evidence. 3rd ed. 2011. This manual was developed as a joint project between The National Academies on Science, Engineering, and Medicine in conjunction with The Federal Judicial Center (the research and education agency of the U.S. judicial system). The purpose of this authoritative work is "to improve the use of science by judges and attorneys," specifically in the context of the 1993 U.S. Supreme Court ruling in Daubert v. Merrell Dow Pharmaceuticals, Inc., 509 U.S. 579 (1993). The reference work contains articles explaining the legal significance of the Daubert decision and evidentiary admissibility of expert testimony on basic scientific principles, forensic identification, statistics, epidemiology, toxicology, medicine, and neuroscience. •• Berger MA. The Admissibility of expert testimony, reference manual on scientific evidence. 3rd ed. 2011. This manual was developed as a joint project between The National Academies on Science, Engineering, and Medicine in conjunction with The Federal Judicial Center (the research and education agency of the U.S. judicial system). The purpose of this authoritative work is "to improve the use of science by judges and attorneys," specifically in the context of the 1993 U.S. Supreme Court ruling in Daubert v. Merrell Dow Pharmaceuticals, Inc., 509 U.S. 579 (1993). The reference work contains articles explaining the legal significance of the Daubert decision and evidentiary admissibility of expert testimony on basic scientific principles, forensic identification, statistics, epidemiology, toxicology, medicine, and neuroscience.
38.
go back to reference • Weiner HM. Forensic approach to medical causation when allergic disease is in the differential diagnosis. Allergy Asthma Proc. 2010;31:1–4. This article describes an allergist's approach to assigning medical causation as well as personal insights on professional responsibilities and conduct. It contains helpful methods and ideas that can be easily incorporated into one's practice.PubMedCrossRef • Weiner HM. Forensic approach to medical causation when allergic disease is in the differential diagnosis. Allergy Asthma Proc. 2010;31:1–4. This article describes an allergist's approach to assigning medical causation as well as personal insights on professional responsibilities and conduct. It contains helpful methods and ideas that can be easily incorporated into one's practice.PubMedCrossRef
Metadata
Title
Medical Causation and Expert Testimony: Allergists at this Intersection of Medicine and Law
Authors
Howard M. Weiner
Ronald E. Gots
Robert P. Hein
Publication date
01-12-2012
Publisher
Current Science Inc.
Published in
Current Allergy and Asthma Reports / Issue 6/2012
Print ISSN: 1529-7322
Electronic ISSN: 1534-6315
DOI
https://doi.org/10.1007/s11882-012-0294-z

Other articles of this Issue 6/2012

Current Allergy and Asthma Reports 6/2012 Go to the issue

Pediatric Allergy and Immunology (JM Portnoy and CE Ciaccio, Section Editors)

A New Model for Environmental Assessment and Exposure Reduction

Pediatric Allergy and Immunology (JM Portnoy and CE Ciaccio, Section Editors)

Innovations in Technology: Social Media and Mobile Technology in the Care of Adolescents with Asthma

Pediatric Allergy and Immunology (JM Portnoy and CE Ciaccio, Section Editors)

IgE-Mediated Cow’s Milk Allergy in Children

Pediatric Allergy and Immunology (JM Portnoy and CE Ciaccio, Section Editors)

Role of Viruses in the Development of Atopic Disease in Pediatric Patients