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BMC Sports Science, Medicine and Rehabilitation

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Open Access 01-12-2010 | Review

Mechanics rules cell biology

Authors: James HC Wang, Bin Li

Published in: BMC Sports Science, Medicine and Rehabilitation | Issue 1/2010

Abstract

Cells in the musculoskeletal system are subjected to various mechanical forces in vivo. Years of research have shown that these mechanical forces, including tension and compression, greatly influence various cellular functions such as gene expression, cell proliferation and differentiation, and secretion of matrix proteins. Cells also use mechanotransduction mechanisms to convert mechanical signals into a cascade of cellular and molecular events. This mini-review provides an overview of cell mechanobiology to highlight the notion that mechanics, mainly in the form of mechanical forces, dictates cell behaviors in terms of both cellular mechanobiological responses and mechanotransduction.

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Title: Mechanics rules cell biology
Authors: James HC Wang
Bin Li
Publication date: 01-12-2010
Publisher: BioMed Central
Published in: BMC Sports Science, Medicine and Rehabilitation / Issue 1/2010
Electronic ISSN: 2052-1847
DOI: https://doi.org/10.1186/1758-2555-2-16

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Mechanics rules cell biology

Abstract

Keynote webinar | Spotlight on medication adherence

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