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CardioVascular and Interventional Radiology

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01-04-2013 | Clinical Investigation

Mechanical Revascularization for Acute Ischemic Stroke: A Single-Center, Retrospective Analysis

Authors: Miran Jeromel, Z. V. Milosevic, I. J. Kocijancic, D. Lovric, V. Svigelj, B. Zvan

Published in: CardioVascular and Interventional Radiology | Issue 2/2013

Abstract

Background

Endovascular mechanical revascularization (thrombectomy) is an increasingly used method for intracranial large vessel recanalization in acute stroke. The purpose of the study was to analyze the recanalization rate, clinical outcome, and complication rate in our stroke patients treated with mechanical revascularization.

Methods

A total of 57 patients with large vessel stroke (within 3 h for anterior and 12 h for posterior circulation) were treated with mechanical revascularization at a single center during 24 months. The primary goal of endovascular treatment using different mechanical devices was recanalization of the occluded vessel. Recanalization rate (reported as thrombolysis in cerebral infarction [TICI] score), clinical outcome (reported as National Institutes of Health Stroke Scale [NIHSS] score and modified Rankin scale [mRS] score), as well as periprocedural complications were analyzed.

Results

The mean age of the patients was 63.1 ± 12.9 years, with baseline median NIHSS score of 14 (interquartile range, 9.5–19). Successful recanalization (TICI 2b or 3) was achieved in 41 (72 %) patients. Twenty patients (35 %) presented with favorable outcome (mRS ≤2) 30 days after stroke. Overall, significant neurological improvement (≥4 NIHSS point reduction) occurred in 36 (63 %) patients. A clinically significant procedure-related adverse events (vessel disruption, peri/postprocedural intracranial bleeding) defined with decline in NIHSS of ≥4 or death occurred in three (5 %) patients.

Conclusions

The study showed a high recanalization rate with improved clinical outcome and a low rate of periprocedural complications in our stroke patients treated with mechanical revascularization. Therefore, we could conclude that endovascular revascularization (primary or in combination with a bridging thrombolysis) was an effective and safe procedure for intracranial large vessel recanalization in acute stroke.

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Title: Mechanical Revascularization for Acute Ischemic Stroke: A Single-Center, Retrospective Analysis
Authors: Miran Jeromel
Z. V. Milosevic
I. J. Kocijancic
D. Lovric
V. Svigelj
B. Zvan
Publication date: 01-04-2013
Publisher: Springer-Verlag
Published in: CardioVascular and Interventional Radiology / Issue 2/2013
Print ISSN: 0174-1551
Electronic ISSN: 1432-086X
DOI: https://doi.org/10.1007/s00270-012-0441-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Mechanical Revascularization for Acute Ischemic Stroke: A Single-Center, Retrospective Analysis

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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