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01-12-2011 | Original Article

Mechanical properties and tissue reinforcement of polypropylene grafts used for pelvic floor repair—an experimental study

Authors: M. Potic, I. Ignjatovic, V. Savic, P. Djekic, G. Radenkovic

Published in: Hernia | Issue 6/2011

Abstract

Purpose

Although grafts can be made from the same materials, the final weave of the product may play a role in the ultimate outcomes or complications. The aim of this experimental study is to evaluate and compare the mechanical properties of the meshes and their influence on biological characteristics as well.

Methods

Full-thickness abdominal wall defect with respect to the peritoneum was primary repaired in 144 male Wister rats using the overlay technique. Monofilament, multifilament and coated polypropylene grafts were used for the repairs. Graft shrinkage, thickness and tensile strength of the explants were analysed after 3 and 6 weeks.

Results

Monofilament grafts showed the highest shrinkage level of 11.97–18% during the investigated period. The thickness of monofilament explants increased gradually, with a maximum of 25.35% after 6 weeks. Multifilament and collagen explants did swell more rapidly in the third week, decreasing thereafter to 19.63–23.04% above the pre-implantation values after 6 weeks. The tensile strength showed a gradual increase over the course of the experiment in all groups.

Conclusion

After graft stabilisation, all samples had similar strength, regardless of the significant differences in the pre-implantation values of graft strength.

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Title: Mechanical properties and tissue reinforcement of polypropylene grafts used for pelvic floor repair—an experimental study
Authors: M. Potic
I. Ignjatovic
V. Savic
P. Djekic
G. Radenkovic
Publication date: 01-12-2011
Publisher: Springer-Verlag
Published in: Hernia / Issue 6/2011
Print ISSN: 1265-4906
Electronic ISSN: 1248-9204
DOI: https://doi.org/10.1007/s10029-011-0829-6

2024 ASCO Annual Meeting

Springer Medicine

Mechanical properties and tissue reinforcement of polypropylene grafts used for pelvic floor repair—an experimental study

Abstract

Purpose

Methods

Results

Conclusion

2024 ASCO Annual Meeting

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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