Top

Published in:

Open Access 01-10-2012 | Oral presentation

Measuring force of infection and vaccine effects on transmission stages in clinical trials of experimental malaria vaccines

Authors: Ingrid Felger, Blaise Genton, Hans-Peter Beck, Tom Smith

Published in: Malaria Journal | Special Issue 1/2012

Excerpt

Molecular parameters of key interest for monitoring the efficacy of anti-malaria interventions are those that quantify effects on transmission or incidence of infection and disease. …

Schoepflin S, Valsangiacomo F, Lin E, Kiniboro B, Mueller I, Felger I: Comparison of Plasmodium falciparum allelic frequency distribution in different endemic settings by high-resolution genotyping. Malar J. 2009, 8: 250-10.1186/1475-2875-8-250.PubMedCentralCrossRefPubMed

Genton B, Betuela I, Felger I, Al-Yaman F, Anders RF, Saul A, Rare L, Baisor M, Lorry K, Brown GV, Pye D, Irving DO, Smith TA, Beck HP, Alpers MP: A recombinant blood-stage malaria vaccine reduces Plasmodium falciparum density and exerts selective pressure on parasite populations in a phase 1-2b trial in Papua New Guinea. J Infect Dis. 2002, 185 (6): 820-827. 10.1086/339342.CrossRefPubMed

Falk N, Maire N, Sama W, Owusu-Agyei S, Smith T, Beck HP, Felger I: Comparison of PCR-RFLP and Genescan-based genotyping for analyzing infection dynamics of Plasmodium falciparum. Am J Trop Med Hyg. 2006, 74 (6): 944-950.PubMed

Sama W, Owusu-Agyei S, Felger I, Vounatsou P, Smith T: An immigration-death model to estimate the duration of malaria infection when detectability of the parasite is imperfect. Stat Med. 2005, 24 (21): 3269-3288. 10.1002/sim.2189.CrossRefPubMed

Title: Measuring force of infection and vaccine effects on transmission stages in clinical trials of experimental malaria vaccines
Authors: Ingrid Felger
Blaise Genton
Hans-Peter Beck
Tom Smith
Publication date: 01-10-2012
Publisher: BioMed Central
Published in: Malaria Journal / Issue Special Issue 1/2012
Electronic ISSN: 1475-2875
DOI: https://doi.org/10.1186/1475-2875-11-S1-O50

Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Reserve your place

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin

Prof. Florian Limbourg

Prof. Anoop Chauhan

Developed by: Springer Medicine

Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Excerpt

Please log in to get access to this content

Other articles of this Special Issue 1/2012

Abstract withdrawn

Towards implementation of rapid diagnostic tests for malaria case management in health centers of the Republic of Congo

New drugs for the control and elimination of malaria: a snapshot of the pipeline

Chemical stability of artemisinin derivatives

Reduction of multiplicity of infections but no change in msp2 genetic diversity in P.falciparum isolates from Congolese children after introduction of artemisin-combination therapies

The paradox of the effectiveness of IRS insecticides (including DDT) and its impacts on human health - what can we fix if it isn’t broken?

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

At a glance: The STEP trials