22-04-2024 | McCune-Albright syndrome | Test Yourself: Answer
A 32-year-old man with upper back pain following a minor fall
Published in: Skeletal Radiology
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The computed tomography (CT) and magnetic resonance imaging (MRI) revealed an expansive lytic lesion with surrounding areas of sclerosis involving the T5 vertebral body, the right costovertebral joint, and the right 5th rib. The lesion displayed a ground glass matrix with a few cystic areas and exhibited heterogeneous contrast enhancement (Fig. 1). Imaging differentials in this case were polyostotic fibrous dysplasia, expansile osteolytic metastasis, Paget’s disease, and Gorham-Stout disease (vanishing bone disease). A CT-guided biopsy was performed, and the histopathological examination indicated a cellular fibrous matrix within the trabecular bone structure (Fig. 2). Both imaging and histopathological findings aligned with the diagnosis of fibrous dysplasia. A skeletal survey subsequent to the diagnosis did not reveal any additional lesion.×
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