Mazabraud syndrome associated with McCune–Albright syndrome

Excerpt

Mazabraud syndrome (MS) is characterized by the combination of skeletal fibrous dysplasia (FD) and intramuscular myxoma(s) [1]. It is a rare syndrome. To the best of our knowledge, 80 cases of MS have been reported since the first description by Henschen in 1926 [2‐5]. MS is frequently associated with McCune–Albright syndrome (MAS). MAS is a rare syndrome whose triad of characteristics is polyostotic FD, café-au-lait spots, and endocrine dysfunction [6]. Twenty-six cases of MS associated with MAS have been reported [3, 4]. Nine of these cases possessed the triad of characteristics. MS is also reported to be associated with some tumors such as osteosarcoma, breast fibrosarcoma, lipoma, ovarian tumors, and uterine tumors [3, 5]. However, to the best of our knowledge, there have been no reports on the association of MS and hemangioma. We report a case of MS associated with MAS demonstrating the triad of characteristics and hemangioma. …