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Archives of Gynecology and Obstetrics

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01-06-2007 | Original Article

Maternal kidney stones during pregnancy and adverse birth outcomes, particularly congenital abnormalities in the offspring

Authors: F. Bánhidy, N. Ács, E. H. Puhó, A. E. Czeizel

Published in: Archives of Gynecology and Obstetrics | Issue 6/2007

Abstract

Objective

The possible adverse birth outcomes, particularly congenital abnormalities (CAs) in pregnant women with kidney stones (KS) previously have not been evaluated; therefore, we decided to study this possible association.

Methods

The population-based data set of the Hungarian Case–Control Surveillance of CAs, 1980–1996, was used for this analysis.

Results

Of 22,843 newborns or fetuses with CAs, 69 (0.30%) had mothers with KS during pregnancy. Of 38,151 matched control newborns without any abnormalities, 147 (0.39%) had KS during pregnancy. KS were associated with an adjusted prevalence odds ratio (POR) with 95% CI of 0.8, 0.6–1.0 for CAs. A higher prevalence of maternal KS during the first trimester of pregnancy was not found in any CA group. There was no higher rate of preterm birth and low birthweight in the newborns of pregnant women with KS.

Conclusions

There is no higher risk for adverse birth outcomes particularly CAs in the offspring of mothers with KS and related drug treatments during pregnancy.

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Title: Maternal kidney stones during pregnancy and adverse birth outcomes, particularly congenital abnormalities in the offspring
Authors: F. Bánhidy
N. Ács
E. H. Puhó
A. E. Czeizel
Publication date: 01-06-2007
Publisher: Springer-Verlag
Published in: Archives of Gynecology and Obstetrics / Issue 6/2007
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI: https://doi.org/10.1007/s00404-006-0277-1

At a glance: The STEP trials

Springer Medicine

Maternal kidney stones during pregnancy and adverse birth outcomes, particularly congenital abnormalities in the offspring

Abstract

Objective

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Objective

Methods

Results

Conclusions

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