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Published in: Archives of Gynecology and Obstetrics 2/2011

01-08-2011 | Materno-fetal medicine

Maternal and fetal leptin and ghrelin levels: relationship with fetal growth

Authors: Filiz Saylan, Gülengül Köken, Emine Cosar, Tülay Köken, Arif Saylan, Dağıstan Tolga Arıöz, Figen Şahin, Reşit Köken, Mehmet Yılmazer

Published in: Archives of Gynecology and Obstetrics | Issue 2/2011

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Abstract

Purpose

In our study, we investigated the influence of plasma levels ghrelin, leptin and other metabolic hormones (ILGF-1 and ILGF-2) in pregnants in regulating fetal body weight and mode of delivery.

Methods

A total of 36 appropriately healthy pregnants 19–36-year-old were involved in the study. Demographic chracteristics, serum ghrelin, leptin, IGF-1 and IGF-2 levels of the pregnants were studied.

Results

Plasma ghrelin and leptin levels did not differ significantly among trimesters and delivery, in contrast to IGF-I and IGF-II concentrations were significantly higher in the first half of the pregnancy (P < 0.05). Serum leptin was significantly associated with mode of delivery (r = 0.231; P = 0.008), BMI (r = 0.462; P = 0.004).

Conclusion

Metabolic factors are associated with fetal growth, but in AGA babies, there were no differences between any parameter and clinical factor.
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Metadata
Title
Maternal and fetal leptin and ghrelin levels: relationship with fetal growth
Authors
Filiz Saylan
Gülengül Köken
Emine Cosar
Tülay Köken
Arif Saylan
Dağıstan Tolga Arıöz
Figen Şahin
Reşit Köken
Mehmet Yılmazer
Publication date
01-08-2011
Publisher
Springer-Verlag
Published in
Archives of Gynecology and Obstetrics / Issue 2/2011
Print ISSN: 0932-0067
Electronic ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-010-1651-6

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