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International Urogynecology Journal
Published in: International Urogynecology Journal 6/2006

01-11-2006 | Case Report

Massive prolapse of the urethral mucosa following periurethral injection of calcium hydroxylapatite for stress urinary incontinence

Authors: Paulo C. R. Palma, Cássio L. Z. Riccetto, Mario Henrique T. Martins, Viviane Herrmann, Rogerio de Fraga, Athanase Billis, Nelson Rodrigues Netto Jr.

Published in: International Urogynecology Journal | Issue 6/2006

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Abstract

The injection of bulking agents into the urethral submucosa is designed to create artificial urethral cushions that can improve urethral coaptation and hence restore continence. Ideally, a urethral bulking agent should be non-immunogenic and biocompatible, leading to minimal inflammatory and fibrotic response. The authors present a case report of a granulomatous reaction leading to urethral prolapse, 3 months after the transurethral injection of calcium hydroxylapatite. To our knowledge, this is the first granulomatous reaction described after calcium hydroxylapatite injection.
Literature
1.
Dmochowski R, Appell R, Klimberg I, Mayer R (2002) Initial clinical results from coaptite injection for stress urinary incontinence comparative clinical study (Abstract). In: Proceedings of the International Continence Society (ICS), 32nd Annual Meeting, Heidelberg, Germany 28-30 Aug. 2002, pp184–185
2.
Pickard R, Reaper J, Wyness L, Cody DJ, McClinton S, N’Dow J (2005) Periurethral injection therapy for urinary incontinence in women (Cochrane Review). In: The Cochrane Library, Issue 1, Update Software, Oxford
3.
Palma PCR, Riccetto CLZ, Netto NR Jr (1996) Urethral pseudolipoma: a complication of periurethral lipo-injection for stress urinary incontinence in a woman. J Urol 155:646PubMedCrossRef
Metadata
Title
Massive prolapse of the urethral mucosa following periurethral injection of calcium hydroxylapatite for stress urinary incontinence
Authors
Paulo C. R. Palma
Cássio L. Z. Riccetto
Mario Henrique T. Martins
Viviane Herrmann
Rogerio de Fraga
Athanase Billis
Nelson Rodrigues Netto Jr.
Publication date
01-11-2006
Publisher
Springer-Verlag
Published in
International Urogynecology Journal / Issue 6/2006
Print ISSN: 0937-3462
Electronic ISSN: 1433-3023
DOI
https://doi.org/10.1007/s00192-005-0038-x

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