Published in:
01-07-2018 | Editorial Commentary
Markers of Maternal and Neonatal Cobalamin Status and Risk Assessment of Neurodevelopmental Disorders in Infants
Authors:
Umesh Kapil, Sadhana Joshi
Published in:
Indian Journal of Pediatrics
|
Issue 7/2018
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Excerpt
Cobalamin deficiency is a major public health problem. Cobalamin requirements increase during pregnancy and poor cobalamin status during pregnancy and in infancy is linked to poor growth and neurodevelopment. Populations which consume plants derived foods, usually have low consumption of animal foods due to their high cost, lack of availability and at times due to religious beliefs. This leads to low serum cobalamin [
1]. Maternal cobalamin concentration during pregnancy is the major determinant of the cobalamin status of the newborn in infancy [
2,
3]. Earlier cross-sectional studies from Norway, Turkey and Brazil have demonstrated correlations between maternal and infant cobalamin status at delivery [
4‐
6]. …