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Open Access 01-01-2017 | Research Article

Mapping the visual brain areas susceptible to phosphene induction through brain stimulation

Authors: Lukas F. Schaeffner, Andrew E. Welchman

Published in: Experimental Brain Research | Issue 1/2017

Abstract

Transcranial magnetic stimulation (TMS) is a non-invasive brain stimulation technique whose effects on neural activity can be uncertain. Within the visual cortex, phosphenes are a useful marker of TMS: They indicate the induction of neural activation that propagates and creates a conscious percept. However, we currently do not know how susceptible different areas of the visual cortex are to TMS-induced phosphenes. In this study, we systematically map out locations in the visual cortex where stimulation triggered phosphenes. We relate this to the retinotopic organization and the location of object- and motion-selective areas, identified by functional magnetic resonance imaging (fMRI) measurements. Our results show that TMS can reliably induce phosphenes in early (V1, V2d, and V2v) and dorsal (V3d and V3a) visual areas close to the interhemispheric cleft. However, phosphenes are less likely in more lateral locations (hMT+/V5 and LOC). This suggests that early and dorsal visual areas are particularly amenable to TMS and that TMS can be used to probe the functional role of these areas.

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Title: Mapping the visual brain areas susceptible to phosphene induction through brain stimulation
Authors: Lukas F. Schaeffner
Andrew E. Welchman
Publication date: 01-01-2017
Publisher: Springer Berlin Heidelberg
Published in: Experimental Brain Research / Issue 1/2017
Print ISSN: 0014-4819
Electronic ISSN: 1432-1106
DOI: https://doi.org/10.1007/s00221-016-4784-4

At a glance: The STEP trials

Springer Medicine

Mapping the visual brain areas susceptible to phosphene induction through brain stimulation

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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