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Journal of Medical Case Reports

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Open Access 01-12-2024 | Mantle Cell Lymphoma | Case report

Colonic lymphomatous polyposis mantle cell lymphoma: a case report and review of literature

Authors: Toukilnan Djiwa, B. B. S. Koui, N. A. Aman, Z. I. Coulibaly, M. Kouyate, K. E. Kouame

Published in: Journal of Medical Case Reports | Issue 1/2024

Abstract

Introduction

Mantle cell lymphoma is a rare lymphoma of the gastrointestinal tract that may present as multiple lymphomatous polyposis. We report a case of lymphomatous polyposis with a review of the literature.

Case report

A 56-year-old man of Black ethnicity and Ivorian nationality with no relevant past medical history, consulted for a sudden onset symptoms of gastrointestinal obstruction, which evolved over 2 days. Macroscopic examination revealed the presence of multiple polyploid formations of the colonic mucosa. Histology showed diffuse lymphomatous proliferation of submucosa consisting off small lymphoid cells with a hyperchromatic crenelated nucleus, suggesting lymphomatous polyposis. Immunohistochemical examination showed expression by the tumor cells of antibodies to CD20, CD5, Bcl2, and cyclin D1. They did not express antibodies to CD10 and CD23. The Ki67 proliferation index was 25%. We have thus retained the diagnosis of mantle cell lymphomatous polyposis.

Conclusion

Multiple lymphomatous polyposis is a rare entity characterized by the presence of numerous gastrointestinal polyploid lesions sometimes involving several segments of the gastrointestinal tract. Typical lymphoma presenting as lymphomatous polyposis is mantle cell lymphoma; although, other tumors may have this aspect.

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Title: Colonic lymphomatous polyposis mantle cell lymphoma: a case report and review of literature
Authors: Toukilnan Djiwa
B. B. S. Koui
N. A. Aman
Z. I. Coulibaly
M. Kouyate
K. E. Kouame
Publication date: 01-12-2024
Publisher: BioMed Central
Keywords: Mantle Cell Lymphoma
Lymphoma
Mucosa Associated Lymphoid Tissue
Rituximab
Rituximab
Published in: Journal of Medical Case Reports / Issue 1/2024
Electronic ISSN: 1752-1947
DOI: https://doi.org/10.1186/s13256-024-04533-z

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Colonic lymphomatous polyposis mantle cell lymphoma: a case report and review of literature

Abstract

Introduction

Case report

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Case report

Conclusion

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