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Open Access 01-12-2014 | Review

Management of persistent anal canal carcinoma after combined-modality therapy: a clinical review

Authors: Daniela Musio, Francesca De Felice, Nicola Raffetto, Vincenzo Tombolini

Published in: Radiation Oncology | Issue 1/2014

Abstract

Anal canal carcinoma is a rare gastro-intestinal cancer. Radiochemotherapy is the recommended primary treatment for patients with non-metastatic carcinoma; surgery is generally reserved for persistent or recurrent disease. Follow-up and surveillance after primary treatment is paramount to classify patients in those with complete remission, persistent or progressive disease. Locally persistent disease represents a clinically significant problem and its management remains subject of some controversy.

The aim of this systematic review is to summarise recommendations for the primary treatment of anal canal carcinoma, to focus on the optimal time to consider residual disease as genuine persistence to proceed with salvage treatment, and to discern how this analysis might inform future clinical trials in management in this class of patients.

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Title: Management of persistent anal canal carcinoma after combined-modality therapy: a clinical review
Authors: Daniela Musio
Francesca De Felice
Nicola Raffetto
Vincenzo Tombolini
Publication date: 01-12-2014
Publisher: BioMed Central
Published in: Radiation Oncology / Issue 1/2014
Electronic ISSN: 1748-717X
DOI: https://doi.org/10.1186/1748-717X-9-39

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Management of persistent anal canal carcinoma after combined-modality therapy: a clinical review

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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