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Current Urology Reports

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01-12-2018 | Lower Urinary Tract Symptoms & Voiding Dysfunction (J Sandhu, Section Editor)

Management of Overactive Bladder Symptoms After Radical Prostatectomy

Authors: Benoit Peyronnet, Benjamin M. Brucker

Published in: Current Urology Reports | Issue 12/2018

Abstract

Purpose of Review

Post-prostatectomy overactive bladder (OAB) is a common and challenging condition to manage. The aim of the present report was to review the recent evidences regarding OAB symptoms that develop in men after prostatectomy and how to manage them.

Recent Findings

The prevalence of OAB after radical prostatectomy may range from 15.2 to 37.8%. Recent studies have highlighted the role of the urethrogenic mechanism (facilitation of the urethrovesical reflex due to stress urinary incontinence (SUI)) in the genesis of post-prostatectomy OAB in a significant proportion of patients. Several other pathophysiological factors such as iatrogenic decentralization of the bladder, defunctionalized bladder due to severe SUI, detrusor underactivity, or bladder outlet obstruction might be involved. The evaluation should aim to identify the underlying mechanism to tailor the treatment, which could range from SUI surgery, to fixing a urethral stricture, improving bladder emptying or using the conventional spectrum of OAB therapies. There is a paucity of data for OAB therapies specific to post-prostatectomy patients, with the exception of solifenacin, tolterodine, and botulinum toxin. There is currently no data on how preoperative management or surgical technique may prevent post-prostatectomy OAB.

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Title: Management of Overactive Bladder Symptoms After Radical Prostatectomy
Authors: Benoit Peyronnet
Benjamin M. Brucker
Publication date: 01-12-2018
Publisher: Springer US
Published in: Current Urology Reports / Issue 12/2018
Print ISSN: 1527-2737
Electronic ISSN: 1534-6285
DOI: https://doi.org/10.1007/s11934-018-0847-3

At a glance: The STEP trials

Springer Medicine

Management of Overactive Bladder Symptoms After Radical Prostatectomy

Abstract

Purpose of Review

Recent Findings

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose of Review

Recent Findings

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