Skip to main content
Top
Published in: Lung 5/2015

01-10-2015

Maintaining Gains Following Pulmonary Rehabilitation

Authors: Edwin K. Luk, Fary Khan, Louis Irving

Published in: Lung | Issue 5/2015

Login to get access

Abstract

Purpose

Pulmonary rehabilitation (PR) is an accepted intervention for individuals with chronic obstructive pulmonary disease. Despite initial improvements following PR, many patients eventually return to baseline function or decline even further. The aim of this study is to look at long-term (>1 year) outcomes following PR.

Methods

This was a prospective cohort study of patients who had completed PR. Participants were invited for an assessment consisting of participant interviews and clinical assessments using standardised instruments.

Results

129 patients between 2003 and 2012 completed rehabilitation and were eligible. 88 patients were included in the analysis. The mean time of the long-term assessment was 22 months following PR. The mean age was 71 years. Mean FEV1 was 46 %. There was a statistically significant (p < 0.001) increase in the incremental shuttle walk test distance of 29.0 m following PR but this gain was lost at the long-term reassessment. Chronic Respiratory Questionnaire (CRQ) scores showed a statistically significant (p < 0.001) increase in all four domains but only the domains of dyspnoea and fatigue remained statistically significant (p < 0.001, p < 0.01, respectively) at the long-term reassessment. Hospital Anxiety and Depression Scale scores reduced following rehabilitation but only the anxiety component was statistically significant (p < 0.01). These improvements persisted at the long-term reassessment but were not statically significant.

Conclusions

This study confirms that many of the functional gains achieved in PR are lost in the longer term. Regular surveillance or monitoring of these patients post-PR is important to identify those requiring further intervention.
Literature
3.
go back to reference Maltais F, Decramer M, Casaburi R, Barreiro E, Burelle Y, Debigare R, Dekhuijzen PN, Franssen F, Gayan-Ramirez G, Gea J, Gosker HR, Gosselink R, Hayot M, Hussain SN, Janssens W, Polkey MI, Roca J, Saey D, Schols AM, Spruit MA, Steiner M, Taivassalo T, Troosters T, Vogiatzis I, Wagner PD (2014) An official American Thoracic Society/European Respiratory Society statement: update on limb muscle dysfunction in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 189(9):e15–62. doi:10.1164/rccm.201402-0373ST PubMedCentralCrossRefPubMed Maltais F, Decramer M, Casaburi R, Barreiro E, Burelle Y, Debigare R, Dekhuijzen PN, Franssen F, Gayan-Ramirez G, Gea J, Gosker HR, Gosselink R, Hayot M, Hussain SN, Janssens W, Polkey MI, Roca J, Saey D, Schols AM, Spruit MA, Steiner M, Taivassalo T, Troosters T, Vogiatzis I, Wagner PD (2014) An official American Thoracic Society/European Respiratory Society statement: update on limb muscle dysfunction in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 189(9):e15–62. doi:10.​1164/​rccm.​201402-0373ST PubMedCentralCrossRefPubMed
4.
go back to reference Monninkhof E, van der Valk P, van der Palen J, van Herwaarden C, Zielhuis G (2003) Effects of a comprehensive self-management programme in patients with chronic obstructive pulmonary disease. Eur Respir J 22(5):815–820CrossRefPubMed Monninkhof E, van der Valk P, van der Palen J, van Herwaarden C, Zielhuis G (2003) Effects of a comprehensive self-management programme in patients with chronic obstructive pulmonary disease. Eur Respir J 22(5):815–820CrossRefPubMed
5.
go back to reference Bourbeau J, Julien M, Maltais F, Rouleau M, Beaupre A, Begin R, Renzi P, Nault D, Borycki E, Schwartzman K, Singh R, Collet JP (2003) Reduction of hospital utilization in patients with chronic obstructive pulmonary disease: a disease-specific self-management intervention. Arch Intern Med 163(5):585–591CrossRefPubMed Bourbeau J, Julien M, Maltais F, Rouleau M, Beaupre A, Begin R, Renzi P, Nault D, Borycki E, Schwartzman K, Singh R, Collet JP (2003) Reduction of hospital utilization in patients with chronic obstructive pulmonary disease: a disease-specific self-management intervention. Arch Intern Med 163(5):585–591CrossRefPubMed
7.
go back to reference Ries AL, Bauldoff GS, Carlin BW, Casaburi R, Emery CF, Mahler DA, Make B, Rochester CL, Zuwallack R, Herrerias C (2007) Pulmonary Rehabilitation: Joint ACCP/AACVPR Evidence-Based Clinical Practice Guidelines. Chest 131(5 Suppl):4S–42S. doi:10.1378/chest.06-2418 CrossRefPubMed Ries AL, Bauldoff GS, Carlin BW, Casaburi R, Emery CF, Mahler DA, Make B, Rochester CL, Zuwallack R, Herrerias C (2007) Pulmonary Rehabilitation: Joint ACCP/AACVPR Evidence-Based Clinical Practice Guidelines. Chest 131(5 Suppl):4S–42S. doi:10.​1378/​chest.​06-2418 CrossRefPubMed
8.
go back to reference Abramson MJ, Crockett AJ, Frith PA, McDonald CF (2006) COPDX: an update of guidelines for the management of chronic obstructive pulmonary disease with a review of recent evidence. Med J Aust 184(7):342–345PubMed Abramson MJ, Crockett AJ, Frith PA, McDonald CF (2006) COPDX: an update of guidelines for the management of chronic obstructive pulmonary disease with a review of recent evidence. Med J Aust 184(7):342–345PubMed
10.
go back to reference Strijbos JH, Postma DS, vanAltena R, Gimeno F, Koeter GH (1996) A comparison between an outpatient hospital-based pulmonary rehabilitation program and a home-care pulmonary rehabilitation program in patients with COPD. A follow-up of 18 months. Chest 109(2):366–372CrossRefPubMed Strijbos JH, Postma DS, vanAltena R, Gimeno F, Koeter GH (1996) A comparison between an outpatient hospital-based pulmonary rehabilitation program and a home-care pulmonary rehabilitation program in patients with COPD. A follow-up of 18 months. Chest 109(2):366–372CrossRefPubMed
11.
go back to reference Singh SJ, Smith DL, Hyland ME, Morgan MD (1998) A short outpatient pulmonary rehabilitation programme: immediate and longer-term effects on exercise performance and quality of life. Respir Med 92(9):1146–1154CrossRefPubMed Singh SJ, Smith DL, Hyland ME, Morgan MD (1998) A short outpatient pulmonary rehabilitation programme: immediate and longer-term effects on exercise performance and quality of life. Respir Med 92(9):1146–1154CrossRefPubMed
12.
go back to reference Foglio K, Bianchi L, Bruletti G, Battista L, Pagani M, Ambrosino N (1999) Long-term effectiveness of pulmonary rehabilitation in patients with chronic airway obstruction. Eur Respir J 13(1):125–132CrossRefPubMed Foglio K, Bianchi L, Bruletti G, Battista L, Pagani M, Ambrosino N (1999) Long-term effectiveness of pulmonary rehabilitation in patients with chronic airway obstruction. Eur Respir J 13(1):125–132CrossRefPubMed
13.
go back to reference Troosters T, Gosselink R, Decramer M (2000) Short- and long-term effects of outpatient rehabilitation in patients with chronic obstructive pulmonary disease: a randomized trial. Am J Med 109(3):207–212CrossRefPubMed Troosters T, Gosselink R, Decramer M (2000) Short- and long-term effects of outpatient rehabilitation in patients with chronic obstructive pulmonary disease: a randomized trial. Am J Med 109(3):207–212CrossRefPubMed
16.
go back to reference Brooks D, Krip B, Mangovski-Alzamora S, Goldstein RS (2002) The effect of postrehabilitation programmes among individuals with chronic obstructive pulmonary disease. Eur Respir J 20(1):20–29CrossRefPubMed Brooks D, Krip B, Mangovski-Alzamora S, Goldstein RS (2002) The effect of postrehabilitation programmes among individuals with chronic obstructive pulmonary disease. Eur Respir J 20(1):20–29CrossRefPubMed
17.
go back to reference Griffiths TL, Burr ML, Campbell IA, Lewis-Jenkins V, Mullins J, Shiels K, Turner-Lawlor PJ, Payne N, Newcombe RG, Ionescu AA, Thomas J, Tunbridge J (2000) Results at 1 year of outpatient multidisciplinary pulmonary rehabilitation: a randomised controlled trial. Lancet 355(9201):362–368CrossRefPubMed Griffiths TL, Burr ML, Campbell IA, Lewis-Jenkins V, Mullins J, Shiels K, Turner-Lawlor PJ, Payne N, Newcombe RG, Ionescu AA, Thomas J, Tunbridge J (2000) Results at 1 year of outpatient multidisciplinary pulmonary rehabilitation: a randomised controlled trial. Lancet 355(9201):362–368CrossRefPubMed
20.
go back to reference Spruit MA, Singh SJ, Garvey C, ZuWallack R, Nici L, Rochester C, Hill K, Holland AE, Lareau SC, Man WD, Pitta F, Sewell L, Raskin J, Bourbeau J, Crouch R, Franssen FM, Casaburi R, Vercoulen JH, Vogiatzis I, Gosselink R, Clini EM, Effing TW, Maltais F, van der Palen J, Troosters T, Janssen DJ, Collins E, Garcia-Aymerich J, Brooks D, Fahy BF, Puhan MA, Hoogendoorn M, Garrod R, Schols AM, Carlin B, Benzo R, Meek P, Morgan M, Rutten-van Molken MP, Ries AL, Make B, Goldstein RS, Dowson CA, Brozek JL, Donner CF, Wouters EF (2013) An official American Thoracic Society/European Respiratory Society statement: key concepts and advances in pulmonary rehabilitation. Am J Respir Crit Care Med 188(8):e13–64. doi:10.1164/rccm.201309-1634ST CrossRefPubMed Spruit MA, Singh SJ, Garvey C, ZuWallack R, Nici L, Rochester C, Hill K, Holland AE, Lareau SC, Man WD, Pitta F, Sewell L, Raskin J, Bourbeau J, Crouch R, Franssen FM, Casaburi R, Vercoulen JH, Vogiatzis I, Gosselink R, Clini EM, Effing TW, Maltais F, van der Palen J, Troosters T, Janssen DJ, Collins E, Garcia-Aymerich J, Brooks D, Fahy BF, Puhan MA, Hoogendoorn M, Garrod R, Schols AM, Carlin B, Benzo R, Meek P, Morgan M, Rutten-van Molken MP, Ries AL, Make B, Goldstein RS, Dowson CA, Brozek JL, Donner CF, Wouters EF (2013) An official American Thoracic Society/European Respiratory Society statement: key concepts and advances in pulmonary rehabilitation. Am J Respir Crit Care Med 188(8):e13–64. doi:10.​1164/​rccm.​201309-1634ST CrossRefPubMed
21.
go back to reference Singh SJ, Morgan MD, Scott S, Walters D, Hardman AE (1992) Development of a shuttle walking test of disability in patients with chronic airways obstruction. Thorax 47(12):1019–1024PubMedCentralCrossRefPubMed Singh SJ, Morgan MD, Scott S, Walters D, Hardman AE (1992) Development of a shuttle walking test of disability in patients with chronic airways obstruction. Thorax 47(12):1019–1024PubMedCentralCrossRefPubMed
22.
go back to reference Guyatt GH, Berman LB, Townsend M, Pugsley SO, Chambers LW (1987) A measure of quality of life for clinical trials in chronic lung disease. Thorax 42(10):773–778PubMedCentralCrossRefPubMed Guyatt GH, Berman LB, Townsend M, Pugsley SO, Chambers LW (1987) A measure of quality of life for clinical trials in chronic lung disease. Thorax 42(10):773–778PubMedCentralCrossRefPubMed
23.
go back to reference Zigmond AS, Snaith RP (1983) The hospital anxiety and depression scale. Acta Psychiatr Scand 67(6):361–370CrossRefPubMed Zigmond AS, Snaith RP (1983) The hospital anxiety and depression scale. Acta Psychiatr Scand 67(6):361–370CrossRefPubMed
24.
go back to reference Schunemann HJ, Puhan M, Goldstein R, Jaeschke R, Guyatt GH (2005) Measurement properties and interpretability of the Chronic respiratory disease questionnaire (CRQ). COPD 2(1):81–89CrossRefPubMed Schunemann HJ, Puhan M, Goldstein R, Jaeschke R, Guyatt GH (2005) Measurement properties and interpretability of the Chronic respiratory disease questionnaire (CRQ). COPD 2(1):81–89CrossRefPubMed
27.
go back to reference Bjelland I, Dahl AA, Haug TT, Neckelmann D (2002) The validity of the Hospital Anxiety and Depression Scale. An updated literature review. J Psychosom Res 52(2):69–77CrossRefPubMed Bjelland I, Dahl AA, Haug TT, Neckelmann D (2002) The validity of the Hospital Anxiety and Depression Scale. An updated literature review. J Psychosom Res 52(2):69–77CrossRefPubMed
30.
go back to reference Bestall JC, Paul EA, Garrod R, Garnham R, Jones RW, Wedzicha AJ (2003) Longitudinal trends in exercise capacity and health status after pulmonary rehabilitation in patients with COPD. Respir Med 97(2):173–180CrossRefPubMed Bestall JC, Paul EA, Garrod R, Garnham R, Jones RW, Wedzicha AJ (2003) Longitudinal trends in exercise capacity and health status after pulmonary rehabilitation in patients with COPD. Respir Med 97(2):173–180CrossRefPubMed
31.
go back to reference Ige OM, Olarewaju RK, Lasebikan VO, Adeniyi YO (2010) Outpatient pulmonary rehabilitation in severe chronic obstructive pulmonary disease. Indian J Chest Dis Allied Sci 52(4):197–201PubMed Ige OM, Olarewaju RK, Lasebikan VO, Adeniyi YO (2010) Outpatient pulmonary rehabilitation in severe chronic obstructive pulmonary disease. Indian J Chest Dis Allied Sci 52(4):197–201PubMed
32.
go back to reference Young P, Dewse M, Fergusson W, Kolbe J (1999) Improvements in outcomes for chronic obstructive pulmonary disease (COPD) attributable to a hospital-based respiratory rehabilitation programme. Aust N Z J Med 29(1):59–65CrossRefPubMed Young P, Dewse M, Fergusson W, Kolbe J (1999) Improvements in outcomes for chronic obstructive pulmonary disease (COPD) attributable to a hospital-based respiratory rehabilitation programme. Aust N Z J Med 29(1):59–65CrossRefPubMed
34.
go back to reference Jenkins S, Cecins N, Collins G (2001) Outcomes and direct costs of a pulmonary rehabilitation service. Physiother Theory Pract 17:67–76CrossRef Jenkins S, Cecins N, Collins G (2001) Outcomes and direct costs of a pulmonary rehabilitation service. Physiother Theory Pract 17:67–76CrossRef
36.
go back to reference Doyle C, Dunt D, Ames D, Selvarajah S (2013) Managing mood disorders in patients attending pulmonary rehabilitation clinics. Int. J Chronic Obstr Pulm Dis 8:15–20. doi:10.2147/COPD.S36378 CrossRef Doyle C, Dunt D, Ames D, Selvarajah S (2013) Managing mood disorders in patients attending pulmonary rehabilitation clinics. Int. J Chronic Obstr Pulm Dis 8:15–20. doi:10.​2147/​COPD.​S36378 CrossRef
37.
go back to reference Keating A, Lee A, Holland AE (2011) What prevents people with chronic obstructive pulmonary disease from attending pulmonary rehabilitation? A systematic review. Chron Respir Dis 8(2):89–99. doi:10.1177/1479972310393756 PubMed Keating A, Lee A, Holland AE (2011) What prevents people with chronic obstructive pulmonary disease from attending pulmonary rehabilitation? A systematic review. Chron Respir Dis 8(2):89–99. doi:10.​1177/​1479972310393756​ PubMed
38.
go back to reference Hornikx M, Van Remoortel H, Demeyer H, Marcal Camillo CA, Decramer M, Janssens W, Troosters T (2013) The influence of comorbidities on outcomes of pulmonary rehabilitation programs in patients with COPD: a systematic review. Biomed Res Int 2013:146148. doi:10.1155/2013/146148 PubMedCentralCrossRefPubMed Hornikx M, Van Remoortel H, Demeyer H, Marcal Camillo CA, Decramer M, Janssens W, Troosters T (2013) The influence of comorbidities on outcomes of pulmonary rehabilitation programs in patients with COPD: a systematic review. Biomed Res Int 2013:146148. doi:10.​1155/​2013/​146148 PubMedCentralCrossRefPubMed
Metadata
Title
Maintaining Gains Following Pulmonary Rehabilitation
Authors
Edwin K. Luk
Fary Khan
Louis Irving
Publication date
01-10-2015
Publisher
Springer US
Published in
Lung / Issue 5/2015
Print ISSN: 0341-2040
Electronic ISSN: 1432-1750
DOI
https://doi.org/10.1007/s00408-015-9751-5

Other articles of this Issue 5/2015

Lung 5/2015 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine