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BMC Neurology
Published in: BMC Neurology 1/2020

01-12-2020 | Magnetic Resonance Imaging | Case report

Magnetic resonance-guided focused ultrasound for mesial temporal lobe epilepsy: a case report

Authors: Keiichi Abe, Toshio Yamaguchi, Hiroki Hori, Masatake Sumi, Shiro Horisawa, Takaomi Taira, Tomokatsu Hori

Published in: BMC Neurology | Issue 1/2020

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Abstract

Background

We report the first case of transcranial magnetic resonance-guided focused ultrasound (MRgFUS) for mesial temporal lobe epilepsy (MTLE).

Case presentation

The target was located 20 mm lateral from the midline and 15 mm above the skull base (left hippocampus). Despite the application of maximal energy, the ablation temperature did not exceed 50 °C, probably because of the low number of effective transducer elements with incident angles below 25 degrees. The skull density ratio was 0.56. Post-operative magnetic resonance imaging did not reveal any lesion and the patient remained almost seizure-free for up to 12 months.

Conclusions

This preliminary case report suggests that MRgFUS may be effective for treating cases of MTLE. Therefore, the safety and feasibility of MRgFUS should be evaluated in future studies with larger numbers of participants and longer follow-up duration.
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Metadata
Title
Magnetic resonance-guided focused ultrasound for mesial temporal lobe epilepsy: a case report
Authors
Keiichi Abe
Toshio Yamaguchi
Hiroki Hori
Masatake Sumi
Shiro Horisawa
Takaomi Taira
Tomokatsu Hori
Publication date
01-12-2020
Publisher
BioMed Central
Published in
BMC Neurology / Issue 1/2020
Electronic ISSN: 1471-2377
DOI
https://doi.org/10.1186/s12883-020-01744-x

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