Published in:
Open Access
01-12-2021 | Magnetic Resonance Imaging | Original Article
Lessons learned during implementation of MR-guided High-Intensity Focused Ultrasound treatment of uterine fibroids
Authors:
K. J. Anneveldt, I. M. Verpalen, I. M. Nijholt, J. R. Dijkstra, R. D. van den Hoed, M. van’t Veer-ten Kate, E. de Boer, J. A. C. van Osch, E. Heijman, H. R. Naber, E. Ista, A. Franx, S. Veersema, J. A. F. Huirne, J. M. Schutte, M. F. Boomsma
Published in:
Insights into Imaging
|
Issue 1/2021
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Abstract
Background
Although promising results have been reported for Magnetic Resonance image-guided High-Intensity Focused Ultrasound (MR-HIFU) treatment of uterine fibroids, this treatment is not yet widely implemented in clinical practice. During the implementation of a new technology, lessons are learned and an institutional learning-curve often has to be completed. The primary aim of our prospective cohort study was to characterize our learning-curve based on our clinical outcomes. Secondary aims included identifying our lessons learned during implementation of MR-HIFU on a technical, patient selection, patient counseling, medical specialists and organizational level.
Results
Our first seventy patients showed significant symptom reduction and improvement of quality of life at 3, 6 and 12 months after MR-HIFU treatment compared to baseline. After the first 25 cases, a clear plateau phase was reached in terms of failed treatments. The median non-perfused volume percentage of these first 25 treatments was 44.6% (range: 0–99.7), compared to a median of 74.7% (range: 0–120.6) for the subsequent treatments.
Conclusions
Our findings describe the learning-curve during the implementation of MR-HIFU and include straightforward suggestions to shorten learning-curves for future users. Moreover, the lessons we learned on technique, patient selection, patient counseling, medical specialists and organization, together with the provided supplements, may be of benefit to other institutions aiming to implement MR-HIFU treatment of uterine fibroids.