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Published in: Skeletal Radiology 8/2020

01-08-2020 | Magnetic Resonance Imaging | Scientific Article

Osteochondral lesion of the talus in children: Are there MRI findings of instability?

Authors: Maya Patel, Michael L. Francavilla, J. Todd R. Lawrence, Christian A. Barrera, Michael K. Nguyen, Cruz Longoria, Jie C. Nguyen

Published in: Skeletal Radiology | Issue 8/2020

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Abstract

Purpose

The purpose of our study was to investigate the performance of MRI findings to predict instability of osteochondral lesion of the talus (OLT) in children and the association between skeletal maturity and lesion stability.

Materials and method

This retrospective IRB-approved and HIPPA-compliant study included children with OLT, who underwent an ankle MRI examination between March 1, 2011, and May 31, 2018. Blinded to the clinical outcome, 2 radiologists retrospectively assessed each MRI study for the presence or absence of various features on the articular side, along the interface, and on the subchondral side of each lesion. Regional skeletal maturity was recorded. Lesion stability was classified using clinical and surgical findings. Mann-Whitney U, Chi-square, Fisher’s exact, and Cochran-Armitage tests were used to compare demographic and MRI findings between children with stable and unstable lesions.

Results

Of the 48 ankles identified, 36 were stable (12.7 + 3.9 years) and 12 were unstable (14.2 + 1.6 years) lesions. None of the lesions presented as a detached fragment. Skeletal immaturity (p = 0.01) was significantly more common in stable than unstable lesions. No other MRI features were found to be significantly different between stable and unstable lesions, which included the presence of an effusion (p = 0.27), intra-articular body (p = 0.25), cartilage changes (p = 0.19), subchondral disruption (p = 0.51), T2-weighted signal intensity rim (p = 0.16), cysts (p = 0.48), marginal sclerosis (p = 0.70), and perilesional marrow edema (p = 0.17).

Conclusion

Results from our study suggest that previously published OCD criteria using conventional MRI are not sufficient for predicting stability of OLT in children. Regional skeletal maturity and older age were more predictive of unstable lesions.
Literature
1.
go back to reference Higuera J, Laguna R, Peral M, Aranda E, Soleto J. Osteochondritis dissecans of the talus during childhood and adolescence. J Pediatr Orthop. 1998;18(3):328–32.PubMed Higuera J, Laguna R, Peral M, Aranda E, Soleto J. Osteochondritis dissecans of the talus during childhood and adolescence. J Pediatr Orthop. 1998;18(3):328–32.PubMed
2.
go back to reference Letts M, Davidson D, Ahmer A. Osteochondritis dissecans of the talus in children. J Pediatr Orthop. 2003;23(5):617–25.PubMedCrossRef Letts M, Davidson D, Ahmer A. Osteochondritis dissecans of the talus in children. J Pediatr Orthop. 2003;23(5):617–25.PubMedCrossRef
3.
go back to reference Kessler JI, Weiss JM, Nikizad H, Gyurdzhyan S, Jacobs JC Jr, Bebchuk JD, et al. Osteochondritis dissecans of the ankle in children and adolescents: demographics and epidemiology. Am J Sports Med. 2014;42(9):2165–71.PubMedCrossRef Kessler JI, Weiss JM, Nikizad H, Gyurdzhyan S, Jacobs JC Jr, Bebchuk JD, et al. Osteochondritis dissecans of the ankle in children and adolescents: demographics and epidemiology. Am J Sports Med. 2014;42(9):2165–71.PubMedCrossRef
4.
go back to reference Naran KN, Zoga AC. Osteochondral lesions about the ankle. Radiol Clin N Am. 2008;46(6):995–1002 v.PubMedCrossRef Naran KN, Zoga AC. Osteochondral lesions about the ankle. Radiol Clin N Am. 2008;46(6):995–1002 v.PubMedCrossRef
5.
go back to reference Berndt AL, Harty M. Transchondral fractures (osteochondritis dissecans) of the talus. J Bone Joint Surg Am. 1959(41-a):988–1020. Berndt AL, Harty M. Transchondral fractures (osteochondritis dissecans) of the talus. J Bone Joint Surg Am. 1959(41-a):988–1020.
6.
go back to reference Edmonds EW, Polousky J. A review of knowledge in osteochondritis dissecans: 123 years of minimal evolution from Konig to the ROCK study group. Clin Orthop Relat Res. 2013;471(4):1118–26.PubMedCrossRef Edmonds EW, Polousky J. A review of knowledge in osteochondritis dissecans: 123 years of minimal evolution from Konig to the ROCK study group. Clin Orthop Relat Res. 2013;471(4):1118–26.PubMedCrossRef
7.
go back to reference Saxena A, Eakin C. Articular talar injuries in athletes: results of microfracture and autogenous bone graft. Am J Sports Med. 2007;35(10):1680–7.PubMedCrossRef Saxena A, Eakin C. Articular talar injuries in athletes: results of microfracture and autogenous bone graft. Am J Sports Med. 2007;35(10):1680–7.PubMedCrossRef
8.
go back to reference Pritsch M, Horoshovski H, Farine I. Arthroscopic treatment of osteochondral lesions of the talus. J Bone Joint Surg Am. 1986;68(6):862–5.PubMedCrossRef Pritsch M, Horoshovski H, Farine I. Arthroscopic treatment of osteochondral lesions of the talus. J Bone Joint Surg Am. 1986;68(6):862–5.PubMedCrossRef
10.
go back to reference De Smet AA, Fisher DR, Burnstein MI, Graf BK, Lange RH. Value of MR imaging in staging osteochondral lesions of the talus (osteochondritis dissecans): results in 14 patients. AJR Am J Roentgenol. 1990;154(3):555–8.PubMedCrossRef De Smet AA, Fisher DR, Burnstein MI, Graf BK, Lange RH. Value of MR imaging in staging osteochondral lesions of the talus (osteochondritis dissecans): results in 14 patients. AJR Am J Roentgenol. 1990;154(3):555–8.PubMedCrossRef
11.
go back to reference Perumal V, Wall E, Babekir N. Juvenile osteochondritis dissecans of the talus. J Pediatr Orthop. 2007;27(7):821–5.PubMedCrossRef Perumal V, Wall E, Babekir N. Juvenile osteochondritis dissecans of the talus. J Pediatr Orthop. 2007;27(7):821–5.PubMedCrossRef
12.
go back to reference Vannini F, Cavallo M, Baldassarri M, Castagnini F, Olivieri A, Ferranti E, et al. Treatment of juvenile osteochondritis dissecans of the talus: current concepts review. Joints. 2014;2(4):188–91.PubMed Vannini F, Cavallo M, Baldassarri M, Castagnini F, Olivieri A, Ferranti E, et al. Treatment of juvenile osteochondritis dissecans of the talus: current concepts review. Joints. 2014;2(4):188–91.PubMed
13.
go back to reference Dipaola JD, Nelson DW, Colville MR. Characterizing osteochondral lesions by magnetic resonance imaging. Arthroscopy. 1991;7(1):101–4.PubMedCrossRef Dipaola JD, Nelson DW, Colville MR. Characterizing osteochondral lesions by magnetic resonance imaging. Arthroscopy. 1991;7(1):101–4.PubMedCrossRef
14.
go back to reference Hepple S, Winson IG, Glew D. Osteochondral lesions of the talus: a revised classification. Foot Ankle Int. 1999;20(12):789–93.PubMedCrossRef Hepple S, Winson IG, Glew D. Osteochondral lesions of the talus: a revised classification. Foot Ankle Int. 1999;20(12):789–93.PubMedCrossRef
15.
go back to reference Mintz DN, Tashjian GS, Connell DA, Deland JT, O'Malley M, Potter HG. Osteochondral lesions of the talus: a new magnetic resonance grading system with arthroscopic correlation. Arthroscopy. 2003;19(4):353–9.PubMedCrossRef Mintz DN, Tashjian GS, Connell DA, Deland JT, O'Malley M, Potter HG. Osteochondral lesions of the talus: a new magnetic resonance grading system with arthroscopic correlation. Arthroscopy. 2003;19(4):353–9.PubMedCrossRef
16.
go back to reference Loomer R, Fisher C, Lloyd-Smith R, Sisler J, Cooney T. Osteochondral lesions of the talus. Am J Sports Med. 1993;21(1):13–9.PubMedCrossRef Loomer R, Fisher C, Lloyd-Smith R, Sisler J, Cooney T. Osteochondral lesions of the talus. Am J Sports Med. 1993;21(1):13–9.PubMedCrossRef
17.
go back to reference Tol JL, Struijs PA, Bossuyt PM, Verhagen RA, van Dijk CN. Treatment strategies in osteochondral defects of the talar dome: a systematic review. Foot Ankle Int. 2000;21(2):119–26.PubMedCrossRef Tol JL, Struijs PA, Bossuyt PM, Verhagen RA, van Dijk CN. Treatment strategies in osteochondral defects of the talar dome: a systematic review. Foot Ankle Int. 2000;21(2):119–26.PubMedCrossRef
18.
go back to reference Lam KY, Siow HM. Conservative treatment for juvenile osteochondritis dissecans of the talus. J Orthop Surg (Hong Kong). 2012;20(2):176–80.CrossRef Lam KY, Siow HM. Conservative treatment for juvenile osteochondritis dissecans of the talus. J Orthop Surg (Hong Kong). 2012;20(2):176–80.CrossRef
19.
go back to reference Heyse TJ, Schuttler KF, Schweitzer A, Timmesfeld N, Efe T, Paletta JR, et al. Juvenile osteochondritis dissecans of the talus: predictors of conservative treatment failure. Arch Orthop Trauma Surg. 2015;135(10):1337–41.PubMedCrossRef Heyse TJ, Schuttler KF, Schweitzer A, Timmesfeld N, Efe T, Paletta JR, et al. Juvenile osteochondritis dissecans of the talus: predictors of conservative treatment failure. Arch Orthop Trauma Surg. 2015;135(10):1337–41.PubMedCrossRef
20.
go back to reference Hembree WC, Wittstein JR, Vinson EN, Queen RM, Larose CR, Singh K, et al. Magnetic resonance imaging features of osteochondral lesions of the talus. Foot Ankle Int. 2012;33(7):591–7.PubMedCrossRef Hembree WC, Wittstein JR, Vinson EN, Queen RM, Larose CR, Singh K, et al. Magnetic resonance imaging features of osteochondral lesions of the talus. Foot Ankle Int. 2012;33(7):591–7.PubMedCrossRef
21.
go back to reference Nguyen JC, Allen H, Liu F, Woo KM, Zhou Z, Kijowski R. Maturation-related changes in T2 relaxation times of cartilage and meniscus of the pediatric knee joint at 3 T. AJR Am J Roentgenol. 2018;211(6):1369–75.PubMedPubMedCentralCrossRef Nguyen JC, Allen H, Liu F, Woo KM, Zhou Z, Kijowski R. Maturation-related changes in T2 relaxation times of cartilage and meniscus of the pediatric knee joint at 3 T. AJR Am J Roentgenol. 2018;211(6):1369–75.PubMedPubMedCentralCrossRef
22.
go back to reference Nguyen JC, Lin B, Potter HG. Maturation-dependent findings in the shoulders of pediatric baseball players on magnetic resonance imaging. Skelet Radiol. 2019;48(7):1087–94.CrossRef Nguyen JC, Lin B, Potter HG. Maturation-dependent findings in the shoulders of pediatric baseball players on magnetic resonance imaging. Skelet Radiol. 2019;48(7):1087–94.CrossRef
23.
go back to reference Elias I, Jung JW, Raikin SM, Schweitzer MW, Carrino JA, Morrison WB. Osteochondral lesions of the talus: change in MRI findings over time in talar lesions without operative intervention and implications for staging systems. Foot Ankle Int. 2006;27(3):157–66.PubMedCrossRef Elias I, Jung JW, Raikin SM, Schweitzer MW, Carrino JA, Morrison WB. Osteochondral lesions of the talus: change in MRI findings over time in talar lesions without operative intervention and implications for staging systems. Foot Ankle Int. 2006;27(3):157–66.PubMedCrossRef
24.
go back to reference Higashiyama I, Kumai T, Takakura Y, Tamail S. Follow-up study of MRI for osteochondral lesion of the talus. Foot Ankle Int. 2000;21(2):127–33.PubMedCrossRef Higashiyama I, Kumai T, Takakura Y, Tamail S. Follow-up study of MRI for osteochondral lesion of the talus. Foot Ankle Int. 2000;21(2):127–33.PubMedCrossRef
25.
go back to reference Nguyen JC, Degnan AJ, Barrera CA, Hee TP, Ganley TJ, Kijowski R. Osteochondritis Dissecans of the elbow in children: MRI findings of instability. AJR Am J Roentgenol. 2019;213(5):1145–51.PubMedCrossRef Nguyen JC, Degnan AJ, Barrera CA, Hee TP, Ganley TJ, Kijowski R. Osteochondritis Dissecans of the elbow in children: MRI findings of instability. AJR Am J Roentgenol. 2019;213(5):1145–51.PubMedCrossRef
26.
go back to reference Kijowski R, Blankenbaker DG, Shinki K, Fine JP, Graf BK, De Smet AA. Juvenile versus adult osteochondritis dissecans of the knee: appropriate MR imaging criteria for instability. Radiology. 2008;248(2):571–8.PubMedCrossRef Kijowski R, Blankenbaker DG, Shinki K, Fine JP, Graf BK, De Smet AA. Juvenile versus adult osteochondritis dissecans of the knee: appropriate MR imaging criteria for instability. Radiology. 2008;248(2):571–8.PubMedCrossRef
27.
go back to reference Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics. 1977;33(1):159–74.PubMedCrossRef Landis JR, Koch GG. The measurement of observer agreement for categorical data. Biometrics. 1977;33(1):159–74.PubMedCrossRef
28.
go back to reference Kramer J, Stiglbauer R, Engel A, Prayer L, Imhof H. MR contrast arthrography (MRA) in osteochondrosis dissecans. J Comput Assist Tomogr. 1992;16(2):254–60.PubMedCrossRef Kramer J, Stiglbauer R, Engel A, Prayer L, Imhof H. MR contrast arthrography (MRA) in osteochondrosis dissecans. J Comput Assist Tomogr. 1992;16(2):254–60.PubMedCrossRef
29.
go back to reference Ellermann J, Johnson CP, Wang L, Macalena JA, Nelson BJ, LaPrade RF. Insights into the epiphyseal cartilage origin and subsequent osseous manifestation of juvenile osteochondritis dissecans with a modified clinical MR imaging protocol: a pilot study. Radiology. 2017;282(3):798–806.PubMedCrossRef Ellermann J, Johnson CP, Wang L, Macalena JA, Nelson BJ, LaPrade RF. Insights into the epiphyseal cartilage origin and subsequent osseous manifestation of juvenile osteochondritis dissecans with a modified clinical MR imaging protocol: a pilot study. Radiology. 2017;282(3):798–806.PubMedCrossRef
30.
go back to reference Uozumi H, Sugita T, Aizawa T, Takahashi A, Ohnuma M, Itoi E. Histologic findings and possible causes of osteochondritis dissecans of the knee. Am J Sports Med. 2009;37(10):2003–8.PubMedCrossRef Uozumi H, Sugita T, Aizawa T, Takahashi A, Ohnuma M, Itoi E. Histologic findings and possible causes of osteochondritis dissecans of the knee. Am J Sports Med. 2009;37(10):2003–8.PubMedCrossRef
31.
go back to reference Eismann EA, Pettit RJ, Wall EJ, Myer GD. Management strategies for osteochondritis dissecans of the knee in the skeletally immature athlete. J Orthop Sports Phys Ther. 2014;44(9):665–79.PubMedCrossRef Eismann EA, Pettit RJ, Wall EJ, Myer GD. Management strategies for osteochondritis dissecans of the knee in the skeletally immature athlete. J Orthop Sports Phys Ther. 2014;44(9):665–79.PubMedCrossRef
32.
go back to reference Samora WP, Chevillet J, Adler B, Young GS, Klingele KE. Juvenile osteochondritis dissecans of the knee: predictors of lesion stability. J Pediatr Orthop. 2012;32(1):1–4.PubMedCrossRef Samora WP, Chevillet J, Adler B, Young GS, Klingele KE. Juvenile osteochondritis dissecans of the knee: predictors of lesion stability. J Pediatr Orthop. 2012;32(1):1–4.PubMedCrossRef
33.
go back to reference Blumer MJ, Longato S, Fritsch H. Structure, formation and role of cartilage canals in the developing bone. Ann Anat. 2008;190(4):305–15.PubMedCrossRef Blumer MJ, Longato S, Fritsch H. Structure, formation and role of cartilage canals in the developing bone. Ann Anat. 2008;190(4):305–15.PubMedCrossRef
34.
go back to reference O'Loughlin PF, Heyworth BE, Kennedy JG. Current concepts in the diagnosis and treatment of osteochondral lesions of the ankle. Am J Sports Med. 2010;38(2):392–404.PubMedCrossRef O'Loughlin PF, Heyworth BE, Kennedy JG. Current concepts in the diagnosis and treatment of osteochondral lesions of the ankle. Am J Sports Med. 2010;38(2):392–404.PubMedCrossRef
35.
go back to reference Millington SA, Grabner M, Wozelka R, Anderson DD, Hurwitz SR, Crandall JR. Quantification of ankle articular cartilage topography and thickness using a high resolution stereophotography system. Osteoarthr Cartil. 2007;15(2):205–11.CrossRef Millington SA, Grabner M, Wozelka R, Anderson DD, Hurwitz SR, Crandall JR. Quantification of ankle articular cartilage topography and thickness using a high resolution stereophotography system. Osteoarthr Cartil. 2007;15(2):205–11.CrossRef
36.
go back to reference Athanasiou KA, Niederauer GG, Schenck RC Jr. Biomechanical topography of human ankle cartilage. Ann Biomed Eng. 1995;23(5):697–704.PubMedCrossRef Athanasiou KA, Niederauer GG, Schenck RC Jr. Biomechanical topography of human ankle cartilage. Ann Biomed Eng. 1995;23(5):697–704.PubMedCrossRef
37.
go back to reference Bruns J, Rosenbach B. Osteochondrosis dissecans of the talus. Comparison of results of surgical treatment in adolescents and adults. Arch Orthop Trauma Surg. 1992;112(1):23–7.PubMedCrossRef Bruns J, Rosenbach B. Osteochondrosis dissecans of the talus. Comparison of results of surgical treatment in adolescents and adults. Arch Orthop Trauma Surg. 1992;112(1):23–7.PubMedCrossRef
38.
go back to reference Kim HK, Laor T, Graham TB, Anton CG, Salisbury SR, Racadio JM, et al. T2 relaxation time changes in distal femoral articular cartilage in children with juvenile idiopathic arthritis: a 3-year longitudinal study. AJR Am J Roentgenol. 2010;195(4):1021–5.PubMedCrossRef Kim HK, Laor T, Graham TB, Anton CG, Salisbury SR, Racadio JM, et al. T2 relaxation time changes in distal femoral articular cartilage in children with juvenile idiopathic arthritis: a 3-year longitudinal study. AJR Am J Roentgenol. 2010;195(4):1021–5.PubMedCrossRef
39.
go back to reference Kang CH, Kim HK, Shiraj S, Anton C, Kim DH, Horn PS. Patellofemoral instability in children: T2 relaxation times of the patellar cartilage in patients with and without patellofemoral instability and correlation with morphological grading of cartilage damage. Pediatr Radiol. 2016;46(8):1134–41.PubMedCrossRef Kang CH, Kim HK, Shiraj S, Anton C, Kim DH, Horn PS. Patellofemoral instability in children: T2 relaxation times of the patellar cartilage in patients with and without patellofemoral instability and correlation with morphological grading of cartilage damage. Pediatr Radiol. 2016;46(8):1134–41.PubMedCrossRef
40.
go back to reference Nguyen JC, Liu F, Blankenbaker DG, Woo KM, Kijowski R. Juvenile osteochondritis dissecans: cartilage T2 mapping of stable medial femoral condyle lesions. Radiology. 2018;288(2):536–43.PubMedCrossRef Nguyen JC, Liu F, Blankenbaker DG, Woo KM, Kijowski R. Juvenile osteochondritis dissecans: cartilage T2 mapping of stable medial femoral condyle lesions. Radiology. 2018;288(2):536–43.PubMedCrossRef
Metadata
Title
Osteochondral lesion of the talus in children: Are there MRI findings of instability?
Authors
Maya Patel
Michael L. Francavilla
J. Todd R. Lawrence
Christian A. Barrera
Michael K. Nguyen
Cruz Longoria
Jie C. Nguyen
Publication date
01-08-2020
Publisher
Springer Berlin Heidelberg
Published in
Skeletal Radiology / Issue 8/2020
Print ISSN: 0364-2348
Electronic ISSN: 1432-2161
DOI
https://doi.org/10.1007/s00256-020-03436-6

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