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Japanese Journal of Radiology

Open Access 26-04-2024 | Magnetic Resonance Imaging | Original Article

Imaging evaluation and volumetric measurement of the space surrounding the diploic veins

Authors: Rei Nakamichi, Toshiaki Taoka, Rintaro Ito, Tadao Yoshida, Michihiko Sone, Shinji Naganawa

Published in: Japanese Journal of Radiology

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Abstract

Purpose

The diploic veins have been suggested to be involved in the excretion of cerebrospinal fluid and intracranial waste products; however, to date, there have been no reports evaluating the space surrounding the diploic veins. Therefore, we aimed to visualize the distribution of gadolinium-based contrast agent (GBCA) in the space surrounding the diploic veins and to evaluate the spatial characteristics.

Materials and methods

Ninety-eight participants (aged 14–84 years) were scanned 4 h after intravenous GBCA injection at Nagoya University Hospital between April 2021 and December 2022. The volume of the space surrounding the diploic veins where the GBCA was distributed was measured using contrast-enhanced T1-weighted images with the application of three-axis motion-sensitized driven equilibrium. The parasagittal dura (PSD) volume adjacent to the superior sagittal sinus was also measured using the same images. Both volumes were corrected for intracranial volume. The correlation between age and the corrected volume was examined using Spearman’s rank correlation coefficient; the relationship between the corrected volume and sex was assessed using the Mann–Whitney U test.

Results

A significant weak negative correlation was observed between the volume of the space surrounding the diploic veins and age (r = −0.330, p < 0.001). Furthermore, there was a significant weak positive correlation between the PSD volume and age (r = 0.385, p < 0.001). Both volumes were significantly greater in men than in women. There was no correlation between the volume of the space surrounding the diploic veins and the volume of the PSD.

Conclusion

The volume of the space surrounding the diploic veins was measurable and, in contrast to the volume of the PSD, was greater in younger participants. This space may be related to intracranial excretory mechanisms and immune responses during youth, requiring further research.
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Metadata
Title
Imaging evaluation and volumetric measurement of the space surrounding the diploic veins
Authors
Rei Nakamichi
Toshiaki Taoka
Rintaro Ito
Tadao Yoshida
Michihiko Sone
Shinji Naganawa
Publication date
26-04-2024
Publisher
Springer Nature Singapore
Published in
Japanese Journal of Radiology
Print ISSN: 1867-1071
Electronic ISSN: 1867-108X
DOI
https://doi.org/10.1007/s11604-024-01572-w