Skip to main content
Top
Published in: Insights into Imaging 1/2020

Open Access 01-12-2020 | Magnetic Resonance Imaging | Original Article

Diagnostic accuracy of ultrasonography in the assessment of anterior knee pain

Authors: Mohammad Abd Alkhalik Basha, Diaa Bakry Eldib, Sameh Abdelaziz Aly, Taghreed M. Azmy, Nader E. M. Mahmoud, Tarek Mohamed Ghandour, Tarek Aly, Shimaa Mostafa, Asmaa M. Elaidy, Hesham Youssef Algazzar

Published in: Insights into Imaging | Issue 1/2020

Login to get access

Abstract

Background

Anterior knee pain (AKP) is a problematic complaint, considered to be the most frequent cause of orthopedic consultancy for knee problems. This study aimed to highlight diagnostic accuracy of ultrasonography as a fast imaging technique in assessment of patients with AKP.

Methods and results

A prospective study was conducted on 143 patients with clinically confirmed AKP. All patients underwent ultrasonography and MRI examinations of the knee. The diagnostic accuracy of ultrasonography compared to MRI for evaluating different findings of possible causes of AKP were analyzed using receiver operating characteristic (ROC) curve and judged by area under curve (AUC). A total of 155 knees were included in the study; 26 knees showed no abnormalities, 19 knees showed positive MRI only, and 110 knees showed positive ultrasonography and MRI. Ultrasonography and MRI reported 11 different findings of possible causes of AKP or related to it. Joint effusion was the most common finding (38%) followed by trochlear cartilage defect (20.6%) and superficial infrapatellar subcutaneous edema (20%). The overall accuracy of ultrasonography was 85.3% sensitivity and 100% specificity. The ultrasonography provided the highest sensitivity (100%) in detecting bipartite patella, followed by 91.5% for joint effusion, and 87.5% for quadriceps tendinopathy. The ROC curve analysis of overall accuracy of ultrasonography showed an AUC of 0.93. The overall Kappa agreement between ultrasonography and MRI was good (k = 0.66).

Conclusion

Ultrasonography can be used to make a swift screening and assessment of painful anterior knee and as an alternative to MRI when it is unavailable or contraindicated.
Literature
1.
go back to reference Sanchis-alfonso V (2014) Holistic approach to understanding anterior knee pain. Clinical implications. Knee Surg Sport Traumatol Arthrosc 22(10):2275–2285CrossRef Sanchis-alfonso V (2014) Holistic approach to understanding anterior knee pain. Clinical implications. Knee Surg Sport Traumatol Arthrosc 22(10):2275–2285CrossRef
2.
go back to reference Whitlock K, Mosier B, Matzkin E (2018) Anterior Knee Pain: Diagnosis and Treatment. In: Katz J., Blauwet C., Schoenfeld A. (eds) Principles of Orthopedic Practice for Primary Care Providers. Springer, Cham. 19:313–327 Whitlock K, Mosier B, Matzkin E (2018) Anterior Knee Pain: Diagnosis and Treatment. In: Katz J., Blauwet C., Schoenfeld A. (eds) Principles of Orthopedic Practice for Primary Care Providers. Springer, Cham. 19:313–327
3.
go back to reference Samim M, Smitaman E, Lawrence D, Moukaddam H (2014) MRI of anterior knee pain. Skeletal Radiol 43(7):875–893PubMedCrossRef Samim M, Smitaman E, Lawrence D, Moukaddam H (2014) MRI of anterior knee pain. Skeletal Radiol 43(7):875–893PubMedCrossRef
4.
go back to reference Sanchis-Alfonso V, Dye SF (2017) How to deal with anterior knee pain in the active young patient. Sports Health 9(4):346–351PubMedCrossRef Sanchis-Alfonso V, Dye SF (2017) How to deal with anterior knee pain in the active young patient. Sports Health 9(4):346–351PubMedCrossRef
5.
go back to reference Hosny S, McClatchie W, Sofat N, Hing BC (2012) Knee pain in adults & adolescents, diagnosis and treatment. Pain Perspect. October. IntechOpen Hosny S, McClatchie W, Sofat N, Hing BC (2012) Knee pain in adults & adolescents, diagnosis and treatment. Pain Perspect. October. IntechOpen
6.
go back to reference Sanchis-Alfonso V, Ordoño F, Subías-López A, Monserrat C (2011) Pathogenesis of anterior knee pain in the active young: is there a relation between the presence of patellofemoral malalignment and pain? In: Sanchis-Alfonso V (eds) Anterior knee pain and patellar instability. Springer, London, pp 51–60 Sanchis-Alfonso V, Ordoño F, Subías-López A, Monserrat C (2011) Pathogenesis of anterior knee pain in the active young: is there a relation between the presence of patellofemoral malalignment and pain? In: Sanchis-Alfonso V (eds) Anterior knee pain and patellar instability. Springer, London, pp 51–60
7.
go back to reference Sanchis-Alfonso V, McConnell J, Monllau JC, Fulkerson JP (2016) Diagnosis and treatment of anterior knee pain. Journal of ISAKOS: Joint Disorders & Orthopaedic Sports Medicine 1(3):161–173CrossRef Sanchis-Alfonso V, McConnell J, Monllau JC, Fulkerson JP (2016) Diagnosis and treatment of anterior knee pain. Journal of ISAKOS: Joint Disorders & Orthopaedic Sports Medicine 1(3):161–173CrossRef
8.
go back to reference Ostlere S (2007) Imaging of anterior knee pain and maltracking. In: imaging of orthopedic sports injuries. In: Vanhoenacker FM, Maas M, Gielen JL (eds) Imaging of Orthopedic Sports Injuries. Medical Radiology (Diagnostic Imaging). Springer, Berlin, Heidelberg Ostlere S (2007) Imaging of anterior knee pain and maltracking. In: imaging of orthopedic sports injuries. In: Vanhoenacker FM, Maas M, Gielen JL (eds) Imaging of Orthopedic Sports Injuries. Medical Radiology (Diagnostic Imaging). Springer, Berlin, Heidelberg
9.
go back to reference De Smet E (2017) Imaging of anterior knee pain. J Belgian Soc Radiol 101:1–2 De Smet E (2017) Imaging of anterior knee pain. J Belgian Soc Radiol 101:1–2
10.
go back to reference Terslev L, Qvistgaard E, Torp-Pedersen S, Laetgaard J, Danneskiold-Samsoe B, Bliddal H (2001) Ultrasound and power Doppler findings in jumper’s knee - preliminary observations. Eur J Ultrasound 13(3):183–189PubMedCrossRef Terslev L, Qvistgaard E, Torp-Pedersen S, Laetgaard J, Danneskiold-Samsoe B, Bliddal H (2001) Ultrasound and power Doppler findings in jumper’s knee - preliminary observations. Eur J Ultrasound 13(3):183–189PubMedCrossRef
11.
go back to reference Fredberg U, Bolvig L (2002) Significance of ultrasonographically detected asymptomatic tendinosis in the patellar and Achilles tendons of elite soccer players: a longitudinal study. Am J Sports Med 30(4):488–491PubMedCrossRef Fredberg U, Bolvig L (2002) Significance of ultrasonographically detected asymptomatic tendinosis in the patellar and Achilles tendons of elite soccer players: a longitudinal study. Am J Sports Med 30(4):488–491PubMedCrossRef
12.
go back to reference Hong A, Liu JN, Gowd AK, Dhawan A, Amin NH (2019) Reliability and accuracy of MRI in orthopedics: a survey of its use and perceived limitations. Clin Med Insights Arthritis Musculoskelet Disord 12:1179544119872972PubMedPubMedCentralCrossRef Hong A, Liu JN, Gowd AK, Dhawan A, Amin NH (2019) Reliability and accuracy of MRI in orthopedics: a survey of its use and perceived limitations. Clin Med Insights Arthritis Musculoskelet Disord 12:1179544119872972PubMedPubMedCentralCrossRef
13.
go back to reference Escala JS, Mellado JM, Olona M, Giné J, Saurí A, Neyret P (2006) Objective patellar instability: MR-based quantitative assessment of potentially associated anatomical features. Knee Surg Sports Traumatol Arthrosc 14(3):264–272PubMedCrossRef Escala JS, Mellado JM, Olona M, Giné J, Saurí A, Neyret P (2006) Objective patellar instability: MR-based quantitative assessment of potentially associated anatomical features. Knee Surg Sports Traumatol Arthrosc 14(3):264–272PubMedCrossRef
14.
go back to reference Corvino A, Catalano O, Corvino F, Sandomenico F, Setola SV, Petrillo A (2016) Superficial temporal artery pseudoaneurysm: what is the role of ultrasound? J Ultrasound 19(3):197–201PubMedPubMedCentralCrossRef Corvino A, Catalano O, Corvino F, Sandomenico F, Setola SV, Petrillo A (2016) Superficial temporal artery pseudoaneurysm: what is the role of ultrasound? J Ultrasound 19(3):197–201PubMedPubMedCentralCrossRef
15.
go back to reference Corvino A, Corvino F, Catalano O, Sandomenico F, Petrillo A (2017) The tail and the string sign: new sonographic features of subcutaneous melanoma metastasis. Ultrasound Med Biol 43(1):370–374PubMedCrossRef Corvino A, Corvino F, Catalano O, Sandomenico F, Petrillo A (2017) The tail and the string sign: new sonographic features of subcutaneous melanoma metastasis. Ultrasound Med Biol 43(1):370–374PubMedCrossRef
16.
go back to reference Catalano O, Alfageme Roldán F, Varelli C, Bard R, Corvino A, Wortsman X (2019) Skin cancer: findings and role of high-resolution ultrasound. J Ultrasound 22(4):423–431 Catalano O, Alfageme Roldán F, Varelli C, Bard R, Corvino A, Wortsman X (2019) Skin cancer: findings and role of high-resolution ultrasound. J Ultrasound 22(4):423–431
17.
go back to reference DeLong ER, DeLong DM, Clarke-Pearson DL (1988) Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics 1:837–845CrossRef DeLong ER, DeLong DM, Clarke-Pearson DL (1988) Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics 1:837–845CrossRef
18.
go back to reference Altman DG (1991) Practical statistics for medical research. Chapman and Hall/CRC Altman DG (1991) Practical statistics for medical research. Chapman and Hall/CRC
19.
20.
21.
go back to reference Draghi F, Ferrozzi G, Urciuoli L, Bortolotto C, Bianchi S (2016) Hoffa’s fat pad abnormalities, knee pain and magnetic resonance imaging in daily practice. Insights Imaging 7(3):373–383PubMedPubMedCentralCrossRef Draghi F, Ferrozzi G, Urciuoli L, Bortolotto C, Bianchi S (2016) Hoffa’s fat pad abnormalities, knee pain and magnetic resonance imaging in daily practice. Insights Imaging 7(3):373–383PubMedPubMedCentralCrossRef
22.
go back to reference Cao J, Zheng B, Meng X et al (2018) A novel ultrasound scanning approach for evaluating femoral cartilage defects of the knee: comparison with routine magnetic resonance imaging. J Orthop Surg Res 13(1):1–12CrossRef Cao J, Zheng B, Meng X et al (2018) A novel ultrasound scanning approach for evaluating femoral cartilage defects of the knee: comparison with routine magnetic resonance imaging. J Orthop Surg Res 13(1):1–12CrossRef
23.
go back to reference Unlu EN, Turhan Y, Kos DM, Safak AA (2017) Assessment of anterior subcutaneous hypersignal on proton-density-weighted MR imaging of the knee and relationship with anterior knee pain. Diagn Interv Imaging 98(4):339–345PubMedCrossRef Unlu EN, Turhan Y, Kos DM, Safak AA (2017) Assessment of anterior subcutaneous hypersignal on proton-density-weighted MR imaging of the knee and relationship with anterior knee pain. Diagn Interv Imaging 98(4):339–345PubMedCrossRef
24.
go back to reference Lee P, Nixion A, Chandratreya A, Murray J (2017) Synovial plica syndrome of the knee: a commonly overlooked cause of anterior knee pain. Surg J (N Y) 3(01):e9–e16CrossRef Lee P, Nixion A, Chandratreya A, Murray J (2017) Synovial plica syndrome of the knee: a commonly overlooked cause of anterior knee pain. Surg J (N Y) 3(01):e9–e16CrossRef
25.
go back to reference Kheiralla OAM (2016) Imaging appearances of synovial plicae syndrome of the knee. Int J Med Res Heal Sci 5(8):140–149 Kheiralla OAM (2016) Imaging appearances of synovial plicae syndrome of the knee. Int J Med Res Heal Sci 5(8):140–149
27.
go back to reference Warden SJ, Kiss ZS, Malara FA, Ooi ABT, Cook JL, Crossley KM (2007) Comparative accuracy of magnetic resonance imaging and ultrasonography in confirming clinically diagnosed patellar tendinopathy. Am J Sports Med 35(3):427–436PubMedCrossRef Warden SJ, Kiss ZS, Malara FA, Ooi ABT, Cook JL, Crossley KM (2007) Comparative accuracy of magnetic resonance imaging and ultrasonography in confirming clinically diagnosed patellar tendinopathy. Am J Sports Med 35(3):427–436PubMedCrossRef
28.
go back to reference Friedman L, Finlay K, Popovich T, Chhem RK (2003) Sonographic findings in patients with anterior knee pain. J Clin Ultrasound 31(2):85–97PubMedCrossRef Friedman L, Finlay K, Popovich T, Chhem RK (2003) Sonographic findings in patients with anterior knee pain. J Clin Ultrasound 31(2):85–97PubMedCrossRef
29.
30.
go back to reference Jacobson JA, Lenchik L, Ruhoy MK, Schweitzer ME, Resnick D (1997) MR imaging of the infrapatellar fat pad of Hoffa. Radiographics 17(3):675–691PubMedCrossRef Jacobson JA, Lenchik L, Ruhoy MK, Schweitzer ME, Resnick D (1997) MR imaging of the infrapatellar fat pad of Hoffa. Radiographics 17(3):675–691PubMedCrossRef
31.
go back to reference Tsavalas N, Karantanas AH (2013) Suprapatellar fat-pad mass effect: MRI findings and correlation with anterior knee pain. AJR Am J Roentgenol 200(3):W291–W296PubMedCrossRef Tsavalas N, Karantanas AH (2013) Suprapatellar fat-pad mass effect: MRI findings and correlation with anterior knee pain. AJR Am J Roentgenol 200(3):W291–W296PubMedCrossRef
32.
go back to reference Gallagher J, Tierney P, Murray P, O’Brien M (2005) The infrapatellar fat pad: anatomy and clinical correlations. Knee Surg Sports Traumatol Arthrosc 13(4):268–272PubMedCrossRef Gallagher J, Tierney P, Murray P, O’Brien M (2005) The infrapatellar fat pad: anatomy and clinical correlations. Knee Surg Sports Traumatol Arthrosc 13(4):268–272PubMedCrossRef
33.
go back to reference Gutierrez LB, Morgan TA, Link T, Feeley B, Motamedi D (2016) Utility of musculoskeletal ultrasound in the diagnosis and treatment of suprapatellar fat pad impingement: a case report. J Clin Case Rep. 6(837):2 Gutierrez LB, Morgan TA, Link T, Feeley B, Motamedi D (2016) Utility of musculoskeletal ultrasound in the diagnosis and treatment of suprapatellar fat pad impingement: a case report. J Clin Case Rep. 6(837):2
34.
go back to reference Gutierrez LB, Morgan TA (2016) Utility of musculoskeletal ultrasound in the diagnosis and treatment of suprapatellar fat pad impingement: a case report. J Clin Case Reports 6(7):7–9CrossRef Gutierrez LB, Morgan TA (2016) Utility of musculoskeletal ultrasound in the diagnosis and treatment of suprapatellar fat pad impingement: a case report. J Clin Case Reports 6(7):7–9CrossRef
35.
go back to reference Tsavalas N, Karantanas AH (2013) Suprapatellar fat-pad mass effect: MRI findings and correlation with anterior knee pain. AJR Am J Roentgenol 200(3):291–296CrossRef Tsavalas N, Karantanas AH (2013) Suprapatellar fat-pad mass effect: MRI findings and correlation with anterior knee pain. AJR Am J Roentgenol 200(3):291–296CrossRef
36.
go back to reference Mikkilineni H, Delzell PB, Andrish J et al (2018) Ultrasound evaluation of infrapatellar fat pad impingement: an exploratory prospective study. Knee 25(2):279–285PubMedCrossRef Mikkilineni H, Delzell PB, Andrish J et al (2018) Ultrasound evaluation of infrapatellar fat pad impingement: an exploratory prospective study. Knee 25(2):279–285PubMedCrossRef
38.
go back to reference Blankstein A, Cohen I, Salai M, Diamant L, Chechick A, Ganel A (2001) Ultrasonography: an imaging modality enabling the diagnosis of bipartite patella. Knee Surg Sport Traumatol Arthrosc 9(4):221–224CrossRef Blankstein A, Cohen I, Salai M, Diamant L, Chechick A, Ganel A (2001) Ultrasonography: an imaging modality enabling the diagnosis of bipartite patella. Knee Surg Sport Traumatol Arthrosc 9(4):221–224CrossRef
39.
go back to reference Corvino A, Sandomenico F, Corvino F, Campanino MR, Verde F, Giurazza F, Catalano O (2020) Utility of gel stand-off pad in the detection of Doppler signal on focal nodular lesions of the skin. J Ultrasound 23(1):45–53PubMedCrossRef Corvino A, Sandomenico F, Corvino F, Campanino MR, Verde F, Giurazza F, Catalano O (2020) Utility of gel stand-off pad in the detection of Doppler signal on focal nodular lesions of the skin. J Ultrasound 23(1):45–53PubMedCrossRef
Metadata
Title
Diagnostic accuracy of ultrasonography in the assessment of anterior knee pain
Authors
Mohammad Abd Alkhalik Basha
Diaa Bakry Eldib
Sameh Abdelaziz Aly
Taghreed M. Azmy
Nader E. M. Mahmoud
Tarek Mohamed Ghandour
Tarek Aly
Shimaa Mostafa
Asmaa M. Elaidy
Hesham Youssef Algazzar
Publication date
01-12-2020
Publisher
Springer Berlin Heidelberg
Published in
Insights into Imaging / Issue 1/2020
Electronic ISSN: 1869-4101
DOI
https://doi.org/10.1186/s13244-020-00914-2

Other articles of this Issue 1/2020

Insights into Imaging 1/2020 Go to the issue