Published in:
Open Access
01-12-2021 | Magnetic Resonance Imaging | Case report
Cerebellar venous thrombosis mimicking a cerebellar tumor due to polycythemia vera: a case report
Authors:
Hongfeng Wen, Di Jin, Yu Chen, Bin Cui, Tianyi Xiao
Published in:
BMC Neurology
|
Issue 1/2021
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Abstract
Background
Cerebral venous thrombosis (CVT) occurs rarely in the general population and is frequently associated with confused clinical findings and delayed diagnosis. Isolated cerebellar cortical vein thrombosis is a very rare phenomenon.
Case presentation
This report describes a case with CVT, which is manifested as space-occupying lesions of the cerebellar hemisphere and mimics a cerebellar tumor at the beginning. The diagnosis of CVT was finalized given the laboratory and brain biopsy findings. The etiology may be related to polycythemia vera with Janus Kinase 2 V617F mutation.
Conclusion
Isolated cerebellar vein thrombosis should be considered when swelling and enhancing cerebellar lesions are detected. Polycythemia vera, especially with a positive JAK2 V617F mutation, may be a rare risk factor for CVT.