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Published in: Current Breast Cancer Reports 2/2023

04-04-2023 | Magnetic Resonance Imaging

Advanced Breast Imaging Modalities — DBT, CEM, MBI, PEM, MRI, AI

Authors: Ahmed Elhatw, Hannah L. Chung, Rasha M. Kamal, Charles De Jesus, Shanen Jean, Varnita Vishwanath, Hanna R. Ferreira Dalla Pria, Miral M. Patel, Mary S. Guirguis, Tanya W. Moseley

Published in: Current Breast Cancer Reports | Issue 2/2023

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Abstract

Purpose of Review

To discuss how advanced breast imaging modalities can supplement standard breast imaging with mammography, ultrasound, and MRI.

Recent Findings

For the last 40–50 years, the primary breast cancer screening examination has been mammography which has undergone many changes from xeromammography, film-screen analog, to digital mammography techniques. Digital breast tomosynthesis (DBT) and contrast-enhanced mammography (CEM) are the most recent advances to digital mammography. Molecular breast imaging (MBI) and positron emission mammography (PEM) are nuclear medicine breast examinations that utilize mammographic positioning and are useful supplements to standard breast imaging examination.

Summary

Advances in mammographic techniques have improved the sensitivity and specificity of mammography in detecting breast cancer, demonstrating the extent of disease, and evaluating the response to systemic treatments. Understanding how advanced mammographic techniques fit in with other available breast imaging examinations helps ensure optimal evaluation to help guide treatment decisions.
Literature
1.
go back to reference •• Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–49. https://doi.org/10.3322/caac.21660. Findings from this study demonstrate the global burden of cancer and illustrate the increasing significance of cancer as a primary cause of death globally.CrossRefPubMed •• Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–49. https://​doi.​org/​10.​3322/​caac.​21660. Findings from this study demonstrate the global burden of cancer and illustrate the increasing significance of cancer as a primary cause of death globally.CrossRefPubMed
7.
go back to reference Pisano ED, Gatsonis C, Hendrick E, Yaffe M, Baum JK, Acharyya S, Conant EF, Fajardo LL, Bassett L, D’Orsi C, Jong R, Rebner M, Digital Mammographic Imaging Screening Trial (DMIST) Investigators Group. Diagnostic performance of digital versus film mammography for breast-cancer screening. N Engl J Med. 2005;353(17):1773–83. https://doi.org/10.1056/NEJMoa052911.CrossRefPubMed Pisano ED, Gatsonis C, Hendrick E, Yaffe M, Baum JK, Acharyya S, Conant EF, Fajardo LL, Bassett L, D’Orsi C, Jong R, Rebner M, Digital Mammographic Imaging Screening Trial (DMIST) Investigators Group. Diagnostic performance of digital versus film mammography for breast-cancer screening. N Engl J Med. 2005;353(17):1773–83. https://​doi.​org/​10.​1056/​NEJMoa052911.CrossRefPubMed
12.
go back to reference Caumo F, Romanucci G, Hunter K, Zorzi M, Brunelli S, Macaskill P, Houssami N. Comparison of breast cancers detected in the Verona screening program following transition to digital breast tomosynthesis screening with cancers detected at digital mammography screening. Breast Cancer Res Treat. 2018;170(2):391–7. https://doi.org/10.1007/s10549-018-4756-4.CrossRefPubMed Caumo F, Romanucci G, Hunter K, Zorzi M, Brunelli S, Macaskill P, Houssami N. Comparison of breast cancers detected in the Verona screening program following transition to digital breast tomosynthesis screening with cancers detected at digital mammography screening. Breast Cancer Res Treat. 2018;170(2):391–7. https://​doi.​org/​10.​1007/​s10549-018-4756-4.CrossRefPubMed
13.
22.
go back to reference Sudhir R, Sannapareddy K, Potlapalli A, Krishnamurthy PB, Buddha S, Koppula V. Diagnostic accuracy of contrast-enhanced digital mammography in breast cancer detection in comparison to tomosynthesis, synthetic 2D mammography and tomosynthesis combined with ultrasound in women with dense breast. Br J Radiol. 2021;94(1118):20201046. https://doi.org/10.1259/bjr.20201046.CrossRefPubMed Sudhir R, Sannapareddy K, Potlapalli A, Krishnamurthy PB, Buddha S, Koppula V. Diagnostic accuracy of contrast-enhanced digital mammography in breast cancer detection in comparison to tomosynthesis, synthetic 2D mammography and tomosynthesis combined with ultrasound in women with dense breast. Br J Radiol. 2021;94(1118):20201046. https://​doi.​org/​10.​1259/​bjr.​20201046.CrossRefPubMed
25.
go back to reference Kamal R, Mansour S, Farouk A, et al. Contrast-enhanced mammography in comparison with dynamic contrast-enhanced MRI: which modality is appropriate for whom? Egyptian Journal of Radiology and Nuclear Medicine. Springer Science and Business Media Deutschland GmbH; 2021. Kamal R, Mansour S, Farouk A, et al. Contrast-enhanced mammography in comparison with dynamic contrast-enhanced MRI: which modality is appropriate for whom? Egyptian Journal of Radiology and Nuclear Medicine. Springer Science and Business Media Deutschland GmbH; 2021.
30.
go back to reference Montrognon F, Clatot F, Berghian A, Douvrin F, Quieffin F, Defta D, Buquet A, Ferret M, Lequesne J, Leheurteur M, Fontanilles M, Georgescu D, Callonnec F. Impact of preoperative staging with contrast-enhanced mammography for localized breast cancer management. Br J Radiol. 2022;95(1134):20210765. https://doi.org/10.1259/bjr.20210765.CrossRefPubMed Montrognon F, Clatot F, Berghian A, Douvrin F, Quieffin F, Defta D, Buquet A, Ferret M, Lequesne J, Leheurteur M, Fontanilles M, Georgescu D, Callonnec F. Impact of preoperative staging with contrast-enhanced mammography for localized breast cancer management. Br J Radiol. 2022;95(1134):20210765. https://​doi.​org/​10.​1259/​bjr.​20210765.CrossRefPubMed
31.
go back to reference Bernardi D, Vatteroni G, Acquaviva A, Valentini M, Sabatino V, Bolengo I, Pellegrini M, Fantò C, Trimboli RM. Contrast-enhanced mammography versus MRI in the evaluation of neoadjuvant therapy response in patients with breast cancer: a prospective study. AJR Am J Roentgenol. 2022;219(6):884–94. https://doi.org/10.2214/AJR.22.27756.CrossRefPubMed Bernardi D, Vatteroni G, Acquaviva A, Valentini M, Sabatino V, Bolengo I, Pellegrini M, Fantò C, Trimboli RM. Contrast-enhanced mammography versus MRI in the evaluation of neoadjuvant therapy response in patients with breast cancer: a prospective study. AJR Am J Roentgenol. 2022;219(6):884–94. https://​doi.​org/​10.​2214/​AJR.​22.​27756.CrossRefPubMed
33.
go back to reference Berg WA, Weinberg IN, Narayanan D, Lobrano ME, Ross E, Amodei L, et al. High-resolution fluorodeoxyglucose positron emission tomography with compression (“positron emission mammography”) is highly accurate in depicting primary breast cancer. Breast J. 2006;12(4):309–23.CrossRefPubMed Berg WA, Weinberg IN, Narayanan D, Lobrano ME, Ross E, Amodei L, et al. High-resolution fluorodeoxyglucose positron emission tomography with compression (“positron emission mammography”) is highly accurate in depicting primary breast cancer. Breast J. 2006;12(4):309–23.CrossRefPubMed
37.
go back to reference •• Le EPV, Wang Y, Huang Y, Hickman S, Gilbert FJ. Artificial intelligence in breast imaging. Clin Radiol. 2019;74(5):357–66. https://doi.org/10.1016/j.crad.2019.02.006. Findings from this study demonstrate that artificial intelligence (AI), once effectively integrated into imaging practices, has the potential to reduce diagnostic errors, increase radiologists’ accuracy, and aid in decision-making.CrossRefPubMed •• Le EPV, Wang Y, Huang Y, Hickman S, Gilbert FJ. Artificial intelligence in breast imaging. Clin Radiol. 2019;74(5):357–66. https://​doi.​org/​10.​1016/​j.​crad.​2019.​02.​006. Findings from this study demonstrate that artificial intelligence (AI), once effectively integrated into imaging practices, has the potential to reduce diagnostic errors, increase radiologists’ accuracy, and aid in decision-making.CrossRefPubMed
Metadata
Title
Advanced Breast Imaging Modalities — DBT, CEM, MBI, PEM, MRI, AI
Authors
Ahmed Elhatw
Hannah L. Chung
Rasha M. Kamal
Charles De Jesus
Shanen Jean
Varnita Vishwanath
Hanna R. Ferreira Dalla Pria
Miral M. Patel
Mary S. Guirguis
Tanya W. Moseley
Publication date
04-04-2023
Publisher
Springer US
Published in
Current Breast Cancer Reports / Issue 2/2023
Print ISSN: 1943-4588
Electronic ISSN: 1943-4596
DOI
https://doi.org/10.1007/s12609-023-00483-5

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