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Open Access 01-06-2021 | Magnetic Resonance Imaging | Cardiac

3D Dixon water-fat LGE imaging with image navigator and compressed sensing in cardiac MRI

Authors: Martin Georg Zeilinger, Marco Wiesmüller, Christoph Forman, Michaela Schmidt, Camila Munoz, Davide Piccini, Karl-Philipp Kunze, Radhouene Neji, René Michael Botnar, Claudia Prieto, Michael Uder, Matthias May, Wolfgang Wuest

Published in: European Radiology | Issue 6/2021

Abstract

Objectives

To evaluate an image-navigated isotropic high-resolution 3D late gadolinium enhancement (LGE) prototype sequence with compressed sensing and Dixon water-fat separation in a clinical routine setting.

Material and methods

Forty consecutive patients scheduled for cardiac MRI were enrolled prospectively and examined with 1.5 T MRI. Overall subjective image quality, LGE pattern and extent, diagnostic confidence for detection of LGE, and scan time were evaluated and compared to standard 2D LGE imaging. Robustness of Dixon fat suppression was evaluated for 3D Dixon LGE imaging. For statistical analysis, the non-parametric Wilcoxon rank sum test was performed.

Results

LGE was rated as ischemic in 9 patients and non-ischemic in 11 patients while it was absent in 20 patients. Image quality and diagnostic confidence were comparable between both techniques (p = 0.67 and p = 0.66, respectively). LGE extent with respect to segmental or transmural myocardial enhancement was identical between 2D and 3D (water-only and in-phase). LGE size was comparable (3D 8.4 ± 7.2 g, 2D 8.7 ± 7.3 g, p = 0.19). Good or excellent fat suppression was achieved in 93% of the 3D LGE datasets. In 6 patients with pericarditis, the 3D sequence with Dixon fat suppression allowed for a better detection of pericardial LGE. Scan duration was significantly longer for 3D imaging (2D median 9:32 min vs. 3D median 10:46 min, p = 0.001).

Conclusion

The 3D LGE sequence provides comparable LGE detection compared to 2D imaging and seems to be superior in evaluating the extent of pericardial involvement in patients suspected with pericarditis due to the robust Dixon fat suppression.

Key Points

• Three-dimensional LGE imaging provides high-resolution detection of myocardial scarring.

• Robust Dixon water-fat separation aids in the assessment of pericardial disease.

• The 2D image navigator technique enables 100% respiratory scan efficacy and permits predictable scan times.

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Title: 3D Dixon water-fat LGE imaging with image navigator and compressed sensing in cardiac MRI
Authors: Martin Georg Zeilinger
Marco Wiesmüller
Christoph Forman
Michaela Schmidt
Camila Munoz
Davide Piccini
Karl-Philipp Kunze
Radhouene Neji
René Michael Botnar
Claudia Prieto
Michael Uder
Matthias May
Wolfgang Wuest
Publication date: 01-06-2021
Publisher: Springer Berlin Heidelberg
Keywords: Magnetic Resonance Imaging
Magnetic Resonance Imaging
Cardiac MRI
Published in: European Radiology / Issue 6/2021
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-020-07517-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

3D Dixon water-fat LGE imaging with image navigator and compressed sensing in cardiac MRI

Abstract

Objectives

Material and methods

Results

Conclusion

Key Points

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Material and methods

Results

Conclusion

Key Points

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