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Diagnostic Pathology
Published in: Diagnostic Pathology 1/2013

Open Access 01-12-2013 | Case Report

Lymphoepithelioma-like carcinoma of the stomach: a case report and review of the literature

Authors: Zeid Bittar, Falko Fend, Leticia Quintanilla-Martinez

Published in: Diagnostic Pathology | Issue 1/2013

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Abstract

A lymphoepithelioma-like carcinoma (LLC), characterized by a carcinoma with stromal heavy lymphocyte infiltration, is one of the histological patterns observed in patients with Epstein-Barr virus (EBV)-associated gastric carcinoma. Although this entity is hard to be recognized in the biopsy specimens, pathologists and clinicians should acknowledge this subset of gastric cancer because it generally has a better prognosis than other forms of EBV-associated gastric carcinomas and conventional gastric carcinomas. This might be due to the fact that the patient's inflammatory response may prevent the spread of tumor through the gastric wall and to the lymph nodes or remote organs.
We report a case of EBV-positive, microsatellite stable LLC as a rare morphologic variant of gastric carcinoma.

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Metadata
Title
Lymphoepithelioma-like carcinoma of the stomach: a case report and review of the literature
Authors
Zeid Bittar
Falko Fend
Leticia Quintanilla-Martinez
Publication date
01-12-2013
Publisher
BioMed Central
Published in
Diagnostic Pathology / Issue 1/2013
Electronic ISSN: 1746-1596
DOI
https://doi.org/10.1186/1746-1596-8-184

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