Skip to main content
Top
Published in: Abdominal Radiology 2/2013

01-04-2013

Lymphoepithelial cyst of the pancreas: comparison of CT findings with other pancreatic cystic lesions

Authors: Won Hwa Kim, Jae Young Lee, Hee Sun Park, Hyung Jin Won, Young Hun Kim, Jin Young Choi, Se Hyung Kim, Joon Koo Han, Byung Ihn Choi

Published in: Abdominal Radiology | Issue 2/2013

Login to get access

Abstract

Objective

To describe the CT findings of lymphoepithelial cysts (LECs) of the pancreas and to investigate the differential findings between LECs and other pancreatic cystic lesions.

Materials and methods

Fifty-eight patients with 8 LECs (M:F = 7:1; mean age 55.1 years), 30 serous cystadenomas (SCA) (M:F = 11:19; 52.5 years), 11 mucinous cystadenomas (MCA) (M:F = 0:11; 47.2 years), and 9 pseudocysts (M:F = 6:3; 50.8 years) were included in this study. Two radiologists analyzed all CT images for 3D location, outer shape, appearance, the presence of calcification, enhancing nodule, and pancreatic duct dilatation. Size of lesions and CT number of cystic portion on precontrast CT were measured. For statistical analysis, Mann–Whitney U test and Fisher’s exact test were used.

Results

75 % (6/8) of LECs showed an extrapancreatic location than all other cystic diseases in terms of 3D location (p < 0.0001). LECs showed variable outer shape without a significant difference from that of SCAs and pseudocysts (p > 0.05), but LECs showed microlobulated surface more frequently than the MCAs (p < 0.05). LECs showed a variable appearance from unilocular to multi-microcystic. CT attenuation of LECs (21.2 ± 7.1 HU) was higher than that of SCAs and MCAs (p = 0.005). Size of LECs (34.0 ± 10.8 mm) was smaller than that of MCAs (p = 0.040). There was no calcification, pancreatic duct dilatation, or enhancing nodules in LECs.

Conclusion

LECs appear as a highly exophytic medium-sized cystic mass with various morphology occurring predominantly in the middle-aged or older male patients.
Literature
2.
go back to reference Goodman P, Kumar D, Balachandran S (1994) Lymphoepithelial cyst of the pancreas. Abdom Imaging 19(2):157–159PubMedCrossRef Goodman P, Kumar D, Balachandran S (1994) Lymphoepithelial cyst of the pancreas. Abdom Imaging 19(2):157–159PubMedCrossRef
3.
go back to reference Kazumori H, Sizuku T, Ueki T, Uchida Y, Yamamoto S (1997) Lymphoepithelial cyst of the pancreas. J Gastroenterol 32(5):700–703PubMedCrossRef Kazumori H, Sizuku T, Ueki T, Uchida Y, Yamamoto S (1997) Lymphoepithelial cyst of the pancreas. J Gastroenterol 32(5):700–703PubMedCrossRef
4.
go back to reference Kim YH, Auh YH, Kim KW, et al. (1998) Lymphoepithelial cysts of the pancreas: CT and sonographic findings. Abdom Imaging 23(2):185–187PubMedCrossRef Kim YH, Auh YH, Kim KW, et al. (1998) Lymphoepithelial cysts of the pancreas: CT and sonographic findings. Abdom Imaging 23(2):185–187PubMedCrossRef
5.
go back to reference Koga H, Takayasu K, Mukai K, et al. (1995) CT of lymphoepithelial cysts of the pancreas. J Comput Assist Tomogr 19(2):221–224PubMedCrossRef Koga H, Takayasu K, Mukai K, et al. (1995) CT of lymphoepithelial cysts of the pancreas. J Comput Assist Tomogr 19(2):221–224PubMedCrossRef
6.
go back to reference Schinke-Nickl DA, Muller MF (1996) Case report: lymphoepithelial cyst of the pancreas. Br J Radiol 69(825):876–878PubMedCrossRef Schinke-Nickl DA, Muller MF (1996) Case report: lymphoepithelial cyst of the pancreas. Br J Radiol 69(825):876–878PubMedCrossRef
10.
go back to reference Fukukura Y, Inoue H, Miyazono N, et al. (1998) Lymphoepithelial cysts of the pancreas: demonstration of lipid component using CT and MRI. J Comput Assist Tomogr 22(2):311–313PubMedCrossRef Fukukura Y, Inoue H, Miyazono N, et al. (1998) Lymphoepithelial cysts of the pancreas: demonstration of lipid component using CT and MRI. J Comput Assist Tomogr 22(2):311–313PubMedCrossRef
11.
go back to reference Ueno S, Muranaka T, Maekawa S, et al. (1994) Radiographic features in lymphoepithelial cyst of the pancreas. Abdom Imaging 19(3):232–234PubMedCrossRef Ueno S, Muranaka T, Maekawa S, et al. (1994) Radiographic features in lymphoepithelial cyst of the pancreas. Abdom Imaging 19(3):232–234PubMedCrossRef
12.
go back to reference Arai T, Kino I, Nakamura S, Ogawa H (1992) Epidermal inclusions in abdominal lymph nodes. Report of two cases studied immunohistochemically. Acta Pathol Jpn 42(2):126–129PubMed Arai T, Kino I, Nakamura S, Ogawa H (1992) Epidermal inclusions in abdominal lymph nodes. Report of two cases studied immunohistochemically. Acta Pathol Jpn 42(2):126–129PubMed
13.
go back to reference Iacono C, Cracco N, Zamboni G, et al. (1996) Lymphoepithelial cyst of the pancreas. Report of two cases and review of the literature. Int J Pancreatol 19(1):71–76. doi:10.1007/BF02788378 PubMed Iacono C, Cracco N, Zamboni G, et al. (1996) Lymphoepithelial cyst of the pancreas. Report of two cases and review of the literature. Int J Pancreatol 19(1):71–76. doi:10.​1007/​BF02788378 PubMed
14.
go back to reference Barbaros U, Erbil Y, Kapran Y, et al. (2004) Lymphoepithelial cyst: a rare cystic tumor of the pancreas which mimics carcinoma. J Periodontol 5(5):392–394 Barbaros U, Erbil Y, Kapran Y, et al. (2004) Lymphoepithelial cyst: a rare cystic tumor of the pancreas which mimics carcinoma. J Periodontol 5(5):392–394
16.
go back to reference Frezza EE, Wachtel MS (2008) Lymphoepithelial cyst of the pancreas tail. Case report and review of the literature. J Periodontol 9(1):46–49 Frezza EE, Wachtel MS (2008) Lymphoepithelial cyst of the pancreas tail. Case report and review of the literature. J Periodontol 9(1):46–49
Metadata
Title
Lymphoepithelial cyst of the pancreas: comparison of CT findings with other pancreatic cystic lesions
Authors
Won Hwa Kim
Jae Young Lee
Hee Sun Park
Hyung Jin Won
Young Hun Kim
Jin Young Choi
Se Hyung Kim
Joon Koo Han
Byung Ihn Choi
Publication date
01-04-2013
Publisher
Springer-Verlag
Published in
Abdominal Radiology / Issue 2/2013
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-012-9910-6

Other articles of this Issue 2/2013

Abdominal Radiology 2/2013 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine