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Annals of Surgical Oncology

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01-04-2009 | Other

Lymph Node Yield as a Prognostic Factor in Cancer Studies—Due to Undersampling of Tumor-Free Lymph Nodes at Higher N Stages?

Author: Konradin Metze, MD, PhD

Published in: Annals of Surgical Oncology | Issue 4/2009

Excerpt

To the Editors: …

Leggett MD, Chen SL, Schneider PD, et al. Prognostic value of lymph node yield and metastatic lymph node ratio in medullary thyroid carcinoma. Ann Surg Oncol 2008 [Online: July 2, 2008]

Telian SH, Bilchik AJ. Significance of the lymph node ratio in stage III colon cancer. Ann Surg Oncol 2008;15:1557–8PubMedCrossRef

Slidell MB, Chang DC, Cameron JL, Wolfgang C, Herman JM, Schulick RD, Choti MA, Pawlik TM. Impact of total lymph node count and lymph node ratio on staging and survival after pancreatectomy for pancreatic adenocarcinoma: a large, population-based analysis. Ann Surg Oncol 2008; 15:165–74PubMedCrossRef

Chen SL Bilchik AJ. Resecting lymph nodes in colon cancer: more than a staging operation? Ann Surg Oncol 2007; 14:2175–6PubMedCrossRef

Swanson RS, Compton CC, Stewart AK, et al. The prognosis of T3N0 colon cancer is dependent on the number of lymph nodes examined. Ann Surg Oncol 2003; 10:65–71PubMedCrossRef

Lee HY, Choi HJ, Park KJ, et al. Prognostic significance of metastatic lymph node ratio in node-positive colon carcinoma. Ann Surg Oncol 2007; 14:1712–7PubMedCrossRef

Govindarajan A, Tan JC, Baxter NN, et al. Variations in surgical treatment and outcomes of patients with pancreatic cancer: a population-based study. Ann Surg Oncol 2008;15:175–85PubMedCrossRef

Metze K. Methodological aspects of prognostic factor studies: some caveats. Sao Paulo Med J 1998; 116:1787–8PubMedCrossRef

Metze K. Methodological problems of grading tumour regression: responders compared to non-responders. J Cancer Res Clin Oncol 1998; 124:281–2PubMedCrossRef

10.

Metze K, Adam RL. Quantification in histopathology – some pitfalls. Braz J Med Biol Res 2005; 38:141–3PubMedCrossRef

11.

Metze K. Dichotomization of continuous data—a pitfall in prognostic factor studies. Pathol Res Pract 2008; 204:213–4PubMedCrossRef

12.

Lorand-Metze I, Pinheiro MP, Ribeiro E, et al. Factors influencing survival in myelodysplastic syndromes in a Brazilian population: comparison of FAB and WHO classifications. Leuk Res 2004; 28:587–94PubMedCrossRef

13.

Delamain MT, Metze K, Marques JF Jr, et al. Optimization of CD34+ collection for autologous transplantation using the evolution of peripheral blood cell counts after mobilization with chemotherapy and G-CSF. Transfus Apher Sci 2006; 34:33–40PubMedCrossRef

14.

Wang X, Wan F, Wang JJ. A common misuse of stepwise regression in studies of ratio of metastatic lymph nodes for gastric cancer. Ann Surg Oncol 2008; 15:1805–6PubMedCrossRef

15.

Rossi CR, Mocellin S, Pasquali S, et al. N-ratio: a novel independent prognostic factor for patients with stage-III cutaneous melanoma. Ann Surg Oncol 2008;15:310–5PubMedCrossRef

16.

Wang, et al. Lymph node ratio: role in the staging of node-positive colon cancer. Ann Surg Oncol 2008; 15:1600–8

17.

Duraker N, Caynak ZC, Bati B. Is there any prognostically different subgroup among patients with stage IIIC (any TN3M0) breast carcinoma? Ann Surg Oncol 2008;15:430–7PubMedCrossRef

Title: Lymph Node Yield as a Prognostic Factor in Cancer Studies—Due to Undersampling of Tumor-Free Lymph Nodes at Higher N Stages?
Author: Konradin Metze, MD, PhD
Publication date: 01-04-2009
Publisher: Springer-Verlag
Published in: Annals of Surgical Oncology / Issue 4/2009
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI: https://doi.org/10.1245/s10434-008-0142-5

At a glance: The STEP trials

Springer Medicine

Lymph Node Yield as a Prognostic Factor in Cancer Studies—Due to Undersampling of Tumor-Free Lymph Nodes at Higher N Stages?

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

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