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Respiratory Research
Published in: Respiratory Research 1/2001

Open Access 01-12-2002 | Review

Lung surfactant in subacute pulmonary disease

Authors: Gehan Devendra, Roger G Spragg

Published in: Respiratory Research | Issue 1/2001

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Abstract

Pulmonary surfactant is a surface active material composed of both lipids and proteins that is produced by alveolar type II pneumocytes. Abnormalities of surfactant in the immature lung or in the acutely inflamed mature lung are well described. However, in a variety of subacute diseases of the mature lung, abnormalities of lung surfactant may also be of importance. These diseases include chronic obstructive pulmonary disease, asthma, cystic fibrosis, interstitial lung disease, pneumonia, and alveolar proteinosis. Understanding of the mechanisms that disturb the lung surfactant system may lead to novel rational therapies for these diseases.
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Metadata
Title
Lung surfactant in subacute pulmonary disease
Authors
Gehan Devendra
Roger G Spragg
Publication date
01-12-2002
Publisher
BioMed Central
Published in
Respiratory Research / Issue 1/2001
Electronic ISSN: 1465-993X
DOI
https://doi.org/10.1186/rr168

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