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BMC Public Health
Published in: BMC Public Health 1/2022

Open Access 01-12-2022 | Lung Cancer | Research

Smaller particular matter, larger risk of female lung cancer incidence? Evidence from 436 Chinese counties

Authors: Huagui Guo, Xin Li, Jing Wei, Weifeng Li, Jiansheng Wu, Yanji Zhang

Published in: BMC Public Health | Issue 1/2022

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Abstract

Background

Many studies have reported the effects of PM2.5 and PM10 on human health, however, it remains unclear whether particular matter with finer particle size has a greater effect.

Objectives

This work aims to examine the varying associations of the incidence rate of female lung cancer with PM1, PM2.5 and PM10 in 436 Chinese cancer registries between 2014 and 2016.

Methods

The effects of PM1, PM2.5 and PM10 were estimated through three regression models, respectively. Mode l only included particular matter, while Model 2 and Model 3 further controlled for time and location factors, and socioeconomic covariates, respectively. Moreover, two sensitivity analyses were performed to investigate the robustness of three particular matte effects. Then, we examined the modifying role of urban-rural division on the effects of PM1, PM2.5 and PM10, respectively.

Results

The change in the incidence rate of female lung cancer relative to its mean was 5.98% (95% CI: 3.40, 8.56%) for PM1, which was larger than the values of PM2.5 and PM10 at 3.75% (95% CI: 2.33, 5.17%) and 1.57% (95% CI: 0.73, 2.41%), respectively. The effects of three particular matters were not sensitive in the two sensitivity analyses. Moreover, urban-rural division positively modified the associations of the incidence rate of female lung cancer with PM1, PM2.5 and PM10.

Conclusions

The effect on the incidence rate of female lung cancer was greater for PM1, followed by PM2.5 and PM10. There were positive modifying roles of urban-rural division on the effects of three particular matters. The finding supports the argument that finer particular matters are more harmful to human health, and also highlights the great significance to develop guidelines for PM1 control and prevention in Chinese setting.
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Metadata
Title
Smaller particular matter, larger risk of female lung cancer incidence? Evidence from 436 Chinese counties
Authors
Huagui Guo
Xin Li
Jing Wei
Weifeng Li
Jiansheng Wu
Yanji Zhang
Publication date
01-12-2022
Publisher
BioMed Central
Published in
BMC Public Health / Issue 1/2022
Electronic ISSN: 1471-2458
DOI
https://doi.org/10.1186/s12889-022-12622-1

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