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01-06-2019 | Lung Cancer | Original Article

Life-threatening complications after pulmonary resection for lung cancer in patients on chronic hemodialysis

Authors: Kenji Tomizawa, Katsuaki Sato, Shuta Ohara, Toshio Fujino, Takamasa Koga, Masaya Nishino, Yoshihisa Kobayashi, Masato Chiba, Masaki Shimoji, Kenichi Suda, Toshiki Takemoto, Tetsuya Mitsudomi

Published in: Surgery Today | Issue 6/2019

Abstract

Purpose

The morbidity and mortality associated with lung cancer surgery in patients on chronic hemodialysis (CHD) is high; however, the relationship between the severity of postoperative complications and clinicopathological features is unclear.

Methods

Among 1214 consecutive patients who underwent pulmonary resection for primary lung cancer in our institute between 2004 and 2015, we identified 21 patients on CHD, who were the subjects of this study. Life-threatening postoperative complications were defined as grade 4 and 5 per the Clavien–Dindo classification.

Results

Fourteen (67%) of these 21 patients suffered postoperative complications, which were life threatening in 5. There was a higher frequency of interstitial pneumonia (IP) in the patients with life-threatening postoperative complications than in those with complications that were not life threatening (p = 0.032). The rates of acute exacerbation and 90-day mortality in the patients with IP were 50% and 75%, respectively. The overall survival (OS) rate of the patients with life-threatening postoperative complications was significantly lower than that of those with complications that were not life threatening (1- and 3-year OS rates: 40% and 0% vs. 80% and 57%, respectively, p = 0.001).

Conclusions

Postoperative mortality and morbidity were high in patients on CHD who underwent pulmonary resection, especially if they had coexisting IP. Although IP is not a contraindication to pulmonary resection, the surgical strategy for CHD patients with IP should be considered carefully.

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Title: Life-threatening complications after pulmonary resection for lung cancer in patients on chronic hemodialysis
Authors: Kenji Tomizawa
Katsuaki Sato
Shuta Ohara
Toshio Fujino
Takamasa Koga
Masaya Nishino
Yoshihisa Kobayashi
Masato Chiba
Masaki Shimoji
Kenichi Suda
Toshiki Takemoto
Tetsuya Mitsudomi
Publication date: 01-06-2019
Publisher: Springer Singapore
Keywords: Lung Cancer
Lung Cancer
Pneumonia
Lung Cancer
Published in: Surgery Today / Issue 6/2019
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI: https://doi.org/10.1007/s00595-019-1773-9

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Life-threatening complications after pulmonary resection for lung cancer in patients on chronic hemodialysis

Abstract

Purpose

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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