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Published in: Acta Neurochirurgica 7/2018

01-07-2018 | Review Article - Spine

Lumbar disk herniation during pregnancy: a review on general management and timing of surgery

Authors: Hugo Ardaillon, Yosef Laviv, Jeffrey E. Arle, Ekkehard M. Kasper

Published in: Acta Neurochirurgica | Issue 7/2018

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Abstract

Study design

Narrative review with case illustration.

Objective

Provide an overview of existing management strategies to suggest a guideline for surgical management of lumbar disk herniation in pregnant women based on time of presentation.

Methods

We performed a narrative review on the topic using the PubMed database. A total of 63 relevant articles published after 1992 were identified, of which 17 fulfilled selection criteria.

Results

A total of 22 published cases of spine surgery for disk herniation during pregnancy were found in 17 studies on the topic. Prone positioning was reported in the majority of cases during the first and early second trimester. C-sections were performed prior to spine surgery in the prone position for the majority of patients operated during the third trimester. The left lateral position with continued pregnancy was preferred during the latter half of the second trimester when delivery of the fetus cannot yet be performed but surgery is indicated.

Conclusion

Spine surgery during pregnancy is a rare scenario but can be performed safely when needed if providers adhere to general guidelines. Surgical approaches and overall management are influenced by the stage of pregnancy.
Literature
1.
go back to reference Abou-Shameh MA, Dosani D, Gopal S, McLaren AG (2006) Lumbar discectomy in pregnancy. Int J Gynaecol Obstet 92:167–169CrossRefPubMed Abou-Shameh MA, Dosani D, Gopal S, McLaren AG (2006) Lumbar discectomy in pregnancy. Int J Gynaecol Obstet 92:167–169CrossRefPubMed
2.
go back to reference ACOG (2011) ACOG Committee Opinion No. 474: nonobstetric surgery during pregnancy. Obstet Gynecol 117:420–421CrossRef ACOG (2011) ACOG Committee Opinion No. 474: nonobstetric surgery during pregnancy. Obstet Gynecol 117:420–421CrossRef
3.
go back to reference Adogwa O, Elsamadicy A, Reiser E, Ziegler C, Freischlag K, Cheng J, Bagley CA (2016) Comparison of surgical outcomes after anterior cervical discectomy and fusion: does the intra-operative use of a microscope improve surgical outcomes. J Spine Surg 2:25–30CrossRefPubMedPubMedCentral Adogwa O, Elsamadicy A, Reiser E, Ziegler C, Freischlag K, Cheng J, Bagley CA (2016) Comparison of surgical outcomes after anterior cervical discectomy and fusion: does the intra-operative use of a microscope improve surgical outcomes. J Spine Surg 2:25–30CrossRefPubMedPubMedCentral
4.
go back to reference Akino K, Akita S, Yakabe A, Mineda T, Hayashi T, Hirano A (2008) Human mesenchymal stem cells may be involved in keloid pathogenesis. Int J Dermatol 47:1112–1117CrossRefPubMed Akino K, Akita S, Yakabe A, Mineda T, Hayashi T, Hirano A (2008) Human mesenchymal stem cells may be involved in keloid pathogenesis. Int J Dermatol 47:1112–1117CrossRefPubMed
5.
go back to reference Al-areibi A, Coveney L, Singh S, Katsiris S (2007) Case report: anesthetic management for sequential cesarean delivery and laminectomy. Can J Anaesth 54:471–474CrossRefPubMed Al-areibi A, Coveney L, Singh S, Katsiris S (2007) Case report: anesthetic management for sequential cesarean delivery and laminectomy. Can J Anaesth 54:471–474CrossRefPubMed
6.
go back to reference Antón Capitán B, Malillos Torán M (2015) Síndrome de cauda equina en paciente embarazada con hernia de disco masiva. Revista Española de Cirugía Ortopédica y Traumatología Antón Capitán B, Malillos Torán M (2015) Síndrome de cauda equina en paciente embarazada con hernia de disco masiva. Revista Española de Cirugía Ortopédica y Traumatología
7.
go back to reference Barash PG (2009) Clinical Anesthesia. Lippincott Williams & Wilkins Barash PG (2009) Clinical Anesthesia. Lippincott Williams & Wilkins
8.
go back to reference Bigos S, Bowyer O, Braen G, Brown K, Deyo R, Haldeman S, Hart JL, Johnson EW, Keller R, Kido D (1994) Acute lower back problems in adults. Rockville, MD: Agency for Health Care Policy and Research Bigos S, Bowyer O, Braen G, Brown K, Deyo R, Haldeman S, Hart JL, Johnson EW, Keller R, Kido D (1994) Acute lower back problems in adults. Rockville, MD: Agency for Health Care Policy and Research
9.
go back to reference Brent RL (1999) Utilization of developmental basic science principles in the evaluation of reproductive risks from pre- and postconception environmental radiation exposures. Teratology 59:182–204CrossRefPubMed Brent RL (1999) Utilization of developmental basic science principles in the evaluation of reproductive risks from pre- and postconception environmental radiation exposures. Teratology 59:182–204CrossRefPubMed
10.
go back to reference Brown MD, Brookfield KF (2004) Lumbar disc excision and cesarean delivery during the same anesthesia. A case report. J Bone Joint Surg Am 86-A:2030–2032CrossRefPubMed Brown MD, Brookfield KF (2004) Lumbar disc excision and cesarean delivery during the same anesthesia. A case report. J Bone Joint Surg Am 86-A:2030–2032CrossRefPubMed
11.
12.
go back to reference Bydon M, Macki M, Abt NB, Sciubba DM, Wolinsky JP, Witham TF, Gokaslan ZL, Bydon A (2015) Clinical and surgical outcomes after lumbar laminectomy: An analysis of 500 patients. Surg Neurol Int 6:S190–S193CrossRefPubMedPubMedCentral Bydon M, Macki M, Abt NB, Sciubba DM, Wolinsky JP, Witham TF, Gokaslan ZL, Bydon A (2015) Clinical and surgical outcomes after lumbar laminectomy: An analysis of 500 patients. Surg Neurol Int 6:S190–S193CrossRefPubMedPubMedCentral
13.
go back to reference Chestnut DH (2012) Nonobstetric Surgery During Pregnancy. Yearb Anesthesiol Pain Manag 2012:335–336CrossRef Chestnut DH (2012) Nonobstetric Surgery During Pregnancy. Yearb Anesthesiol Pain Manag 2012:335–336CrossRef
14.
go back to reference Cohen-Kerem R, Railton C, Oren D, Lishner M, Koren G (2005) Pregnancy outcome following non-obstetric surgical intervention. Am J Surg 190:467–473CrossRefPubMed Cohen-Kerem R, Railton C, Oren D, Lishner M, Koren G (2005) Pregnancy outcome following non-obstetric surgical intervention. Am J Surg 190:467–473CrossRefPubMed
15.
go back to reference Coleman MT, Trianfo VA, Rund DA (1997) Nonobstetric emergencies in pregnancy: trauma and surgical conditions. Am J Obstet Gynecol 177:497–502CrossRefPubMed Coleman MT, Trianfo VA, Rund DA (1997) Nonobstetric emergencies in pregnancy: trauma and surgical conditions. Am J Obstet Gynecol 177:497–502CrossRefPubMed
16.
go back to reference Crowhurst JA (2002) Anaesthesia for non-obstetric surgery during pregnancy. Acta Anaesthesiol Belg 53:295–297PubMed Crowhurst JA (2002) Anaesthesia for non-obstetric surgery during pregnancy. Acta Anaesthesiol Belg 53:295–297PubMed
17.
go back to reference Dupont J, Pierre A, Froment P, Moreau C (2003) The insulin-like growth factor axis in cell cycle progression. Horm Metab Res 35:740–750CrossRefPubMed Dupont J, Pierre A, Froment P, Moreau C (2003) The insulin-like growth factor axis in cell cycle progression. Horm Metab Res 35:740–750CrossRefPubMed
18.
go back to reference Edwards DRV, Aldridge T, Baird DD, Funk MJ, Savitz DA, Hartmann KE (2012) Periconceptional over-the-counter nonsteroidal anti-inflammatory drug exposure and risk for spontaneous abortion. Obstet Gynecol 120:113–122CrossRefPubMed Edwards DRV, Aldridge T, Baird DD, Funk MJ, Savitz DA, Hartmann KE (2012) Periconceptional over-the-counter nonsteroidal anti-inflammatory drug exposure and risk for spontaneous abortion. Obstet Gynecol 120:113–122CrossRefPubMed
19.
go back to reference Fager CA (1994) Observations on spontaneous recovery from intervertebral disc herniation. Surg Neurol 42:282–286CrossRefPubMed Fager CA (1994) Observations on spontaneous recovery from intervertebral disc herniation. Surg Neurol 42:282–286CrossRefPubMed
20.
go back to reference Fahy UM, Oni M, Findlay D, Sell P (1998) Surgical management of herniated lumbar disc in pregnancy. J Obstet Gynaecol 18:544–545CrossRefPubMed Fahy UM, Oni M, Findlay D, Sell P (1998) Surgical management of herniated lumbar disc in pregnancy. J Obstet Gynaecol 18:544–545CrossRefPubMed
21.
go back to reference Flickinger JC (2011) A radiobiological analysis of multicenter data for postoperative keloid radiotherapy. Int J Radiat Oncol Biol Phys 79:1164–1170CrossRefPubMed Flickinger JC (2011) A radiobiological analysis of multicenter data for postoperative keloid radiotherapy. Int J Radiat Oncol Biol Phys 79:1164–1170CrossRefPubMed
22.
go back to reference Garmel SH, Guzelian GA, D’Alton JG, D’Alton ME (1997) Lumbar disk disease in pregnancy. Obstet Gynecol 89:821–822CrossRefPubMed Garmel SH, Guzelian GA, D’Alton JG, D’Alton ME (1997) Lumbar disk disease in pregnancy. Obstet Gynecol 89:821–822CrossRefPubMed
23.
go back to reference Geftler A, Sasson A, Shelef I, Perry ZH, Atar D (2015) Cauda equina syndrome in a 36 week gravida patient. Isr Med Assoc J 17:522–523PubMed Geftler A, Sasson A, Shelef I, Perry ZH, Atar D (2015) Cauda equina syndrome in a 36 week gravida patient. Isr Med Assoc J 17:522–523PubMed
24.
go back to reference Gupta P, Gurumurthy M, Gangineni K, Anarabasu A, Keay SD (2008) Acute presentation of cauda equina syndrome in the third trimester of pregnancy. Eur J Obstet Gynecol Reprod Biol 140:279–281CrossRefPubMed Gupta P, Gurumurthy M, Gangineni K, Anarabasu A, Keay SD (2008) Acute presentation of cauda equina syndrome in the third trimester of pregnancy. Eur J Obstet Gynecol Reprod Biol 140:279–281CrossRefPubMed
26.
27.
go back to reference Hamilton BE MJ, Osterman MJK, et al. (2015) Births: Final data for 2014. National Vital Statistics Reports Vol. 64, No. 12 Hamilton BE MJ, Osterman MJK, et al. (2015) Births: Final data for 2014. National Vital Statistics Reports Vol. 64, No. 12
28.
go back to reference Hayakawa K, Mizutani J, Suzuki N, Haas C, Kondo A, Otsuka S, Fukuoka M, Otsuka T (2016) Surgical management of the pregnant patient with lumbar disc herniation in the latter stage of the second trimester. Spine Hayakawa K, Mizutani J, Suzuki N, Haas C, Kondo A, Otsuka S, Fukuoka M, Otsuka T (2016) Surgical management of the pregnant patient with lumbar disc herniation in the latter stage of the second trimester. Spine
29.
go back to reference Iyilikçi L, Erbayraktar S, Tural AN, Celik M, Sannav S (2004) Anesthetic management of lumbar discectomy in a pregnant patient. J Anesth 18:45–47CrossRefPubMed Iyilikçi L, Erbayraktar S, Tural AN, Celik M, Sannav S (2004) Anesthetic management of lumbar discectomy in a pregnant patient. J Anesth 18:45–47CrossRefPubMed
30.
go back to reference Kathirgamanathan A, Jardine AD, Levy DM, Grevitt MP (2006) Lumbar disc surgery in the third trimester—with the fetus in utero. Int J Obstet Anesth 15:181–182CrossRefPubMed Kathirgamanathan A, Jardine AD, Levy DM, Grevitt MP (2006) Lumbar disc surgery in the third trimester—with the fetus in utero. Int J Obstet Anesth 15:181–182CrossRefPubMed
31.
go back to reference Katz JD, Hook R, Barash PG (1977) Fetal heart rate monitoring in patients undergoing surgery. Surv Anesthesiol 21:286–287 Katz JD, Hook R, Barash PG (1977) Fetal heart rate monitoring in patients undergoing surgery. Surv Anesthesiol 21:286–287
32.
go back to reference Kim HS, Kim SW, Lee SM, Ho S (2007) Endoscopic discectomy for the cauda equina syndrome during third trimester of pregnancy. J Korean Neurosurg Soc 42:419CrossRefPubMedPubMedCentral Kim HS, Kim SW, Lee SM, Ho S (2007) Endoscopic discectomy for the cauda equina syndrome during third trimester of pregnancy. J Korean Neurosurg Soc 42:419CrossRefPubMedPubMedCentral
33.
go back to reference LaBan MM, Perrin JC, Latimer FR (1983) Pregnancy and the herniated lumbar disc. Arch Phys Med Rehabil 64:319–321PubMed LaBan MM, Perrin JC, Latimer FR (1983) Pregnancy and the herniated lumbar disc. Arch Phys Med Rehabil 64:319–321PubMed
34.
go back to reference LaBan MM, Rapp NS, von Oeyen P, Meerschaert JR (1995) The lumbar herniated disk of pregnancy: a report of six cases identified by magnetic resonance imaging. Arch Phys Med Rehabil 76:476–479CrossRefPubMed LaBan MM, Rapp NS, von Oeyen P, Meerschaert JR (1995) The lumbar herniated disk of pregnancy: a report of six cases identified by magnetic resonance imaging. Arch Phys Med Rehabil 76:476–479CrossRefPubMed
35.
36.
go back to reference MacLennan AH, Nicolson R, Green RC, Bath M (1986) Serum relaxin and pelvic pain of pregnancy. Lancet 2:243–245CrossRefPubMed MacLennan AH, Nicolson R, Green RC, Bath M (1986) Serum relaxin and pelvic pain of pregnancy. Lancet 2:243–245CrossRefPubMed
37.
go back to reference Martel CG, Volpi-Abadie J, Ural K (2015) Anesthetic management of the parturient for lumbar disc surgery in the prone position. Ochsner J 15:259–261PubMedPubMedCentral Martel CG, Volpi-Abadie J, Ural K (2015) Anesthetic management of the parturient for lumbar disc surgery in the prone position. Ochsner J 15:259–261PubMedPubMedCentral
38.
go back to reference Marulasiddappa V, Raghavendra B, Nethra H (2014) Anaesthetic management of a pregnant patient with intracranial space occupying lesion for craniotomy. Indian J Anaesth 58:739–741CrossRefPubMedPubMedCentral Marulasiddappa V, Raghavendra B, Nethra H (2014) Anaesthetic management of a pregnant patient with intracranial space occupying lesion for craniotomy. Indian J Anaesth 58:739–741CrossRefPubMedPubMedCentral
39.
go back to reference Matthews LJ, McConda DB, Lalli TAJ, Daffner SD (2015) Orthostetrics: management of orthopedic conditions in the pregnant patient. Orthopedics 38:e874–e880CrossRefPubMed Matthews LJ, McConda DB, Lalli TAJ, Daffner SD (2015) Orthostetrics: management of orthopedic conditions in the pregnant patient. Orthopedics 38:e874–e880CrossRefPubMed
40.
go back to reference Moon JH, Kwak SS, Park G, Jung HY, Yoon BS, Park J, Ryu KS, Choi SC, Maeng I, Kim B, Jun EK, Kim S, Kim A, Oh S, Kim H, Kim KD, You S (2008) Isolation and characterization of multipotent human keloid-derived mesenchymal-like stem cells. Stem Cells Dev 17:713–724CrossRefPubMed Moon JH, Kwak SS, Park G, Jung HY, Yoon BS, Park J, Ryu KS, Choi SC, Maeng I, Kim B, Jun EK, Kim S, Kim A, Oh S, Kim H, Kim KD, You S (2008) Isolation and characterization of multipotent human keloid-derived mesenchymal-like stem cells. Stem Cells Dev 17:713–724CrossRefPubMed
41.
go back to reference Nielsen GL (2001) Risk of adverse birth outcome and miscarriage in pregnant users of non-steroidal anti-inflammatory drugs: population based observational study and case–control study. BMJ 322:266–270CrossRefPubMedPubMedCentral Nielsen GL (2001) Risk of adverse birth outcome and miscarriage in pregnant users of non-steroidal anti-inflammatory drugs: population based observational study and case–control study. BMJ 322:266–270CrossRefPubMedPubMedCentral
43.
go back to reference Ninke T, Thoma-Jennerwein S, Blunk J, Annecke T (2015) Anesthesia and pain management during pregnancy. Anaesthesist 64:347–356CrossRefPubMed Ninke T, Thoma-Jennerwein S, Blunk J, Annecke T (2015) Anesthesia and pain management during pregnancy. Anaesthesist 64:347–356CrossRefPubMed
44.
go back to reference Ochi H, Ohno R, Kubota M, Hanyu R, Sakai K, Sugawara Y, Mukasa F, Kaneko K (2014) Case report: The operation for the lumbar disk herniation just after cesarean delivery in the third trimester of pregnancy. Int J Surg Case Rep 5:1178–1182CrossRefPubMedPubMedCentral Ochi H, Ohno R, Kubota M, Hanyu R, Sakai K, Sugawara Y, Mukasa F, Kaneko K (2014) Case report: The operation for the lumbar disk herniation just after cesarean delivery in the third trimester of pregnancy. Int J Surg Case Rep 5:1178–1182CrossRefPubMedPubMedCentral
45.
go back to reference Orvieto R, Achiron A, Ben-Rafael Z, Gelernter I, Achiron R (1994) Low-back pain of pregnancy. Acta Obstet Gynecol Scand 73:209–214CrossRefPubMed Orvieto R, Achiron A, Ben-Rafael Z, Gelernter I, Achiron R (1994) Low-back pain of pregnancy. Acta Obstet Gynecol Scand 73:209–214CrossRefPubMed
46.
go back to reference Park SH, Kim MJ, Kwon J, Park JP, Park MS, Lim JS, Kim JH, Kim KW (2007) Solitary fibrous tumor arising from stomach: CT findings. Yonsei Med J 48:1056–1060CrossRefPubMedPubMedCentral Park SH, Kim MJ, Kwon J, Park JP, Park MS, Lim JS, Kim JH, Kim KW (2007) Solitary fibrous tumor arising from stomach: CT findings. Yonsei Med J 48:1056–1060CrossRefPubMedPubMedCentral
47.
go back to reference Ray JG, Vermeulen MJ, Bharatha A, Montanera WJ, Park AL (2016) Association between MRI exposure during pregnancy and fetal and childhood outcomes. JAMA 316:952–961CrossRefPubMed Ray JG, Vermeulen MJ, Bharatha A, Montanera WJ, Park AL (2016) Association between MRI exposure during pregnancy and fetal and childhood outcomes. JAMA 316:952–961CrossRefPubMed
48.
go back to reference Timothy J, Anthony R, Tyagi A, Porter D, van Hille PT (1999) A case of delayed diagnosis of the cauda equina syndrome in pregnancy. Aust N Z J Obstet Gynaecol 39:260–261CrossRefPubMed Timothy J, Anthony R, Tyagi A, Porter D, van Hille PT (1999) A case of delayed diagnosis of the cauda equina syndrome in pregnancy. Aust N Z J Obstet Gynaecol 39:260–261CrossRefPubMed
49.
go back to reference Vougioukas VI, Kyroussis G, Gläsker S, Tatagiba M, Scheufler KM (2004) Neurosurgical interventions during pregnancy and the puerperium: clinical considerations and management. Acta Neurochir 146:1287–1291, discussion 1291–1282CrossRefPubMed Vougioukas VI, Kyroussis G, Gläsker S, Tatagiba M, Scheufler KM (2004) Neurosurgical interventions during pregnancy and the puerperium: clinical considerations and management. Acta Neurochir 146:1287–1291, discussion 1291–1282CrossRefPubMed
Metadata
Title
Lumbar disk herniation during pregnancy: a review on general management and timing of surgery
Authors
Hugo Ardaillon
Yosef Laviv
Jeffrey E. Arle
Ekkehard M. Kasper
Publication date
01-07-2018
Publisher
Springer Vienna
Published in
Acta Neurochirurgica / Issue 7/2018
Print ISSN: 0001-6268
Electronic ISSN: 0942-0940
DOI
https://doi.org/10.1007/s00701-017-3098-z

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