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Current Urology Reports
Published in: Current Urology Reports 10/2014

01-10-2014 | Lower Urinary Tract Symptoms & Voiding Dysfunction (H Goldman and G Badlani, Section Editors)

Lower Urinary Tract Symptoms in Women with Diabetes Mellitus: A Current Review

Authors: Rebecca James, Adonis Hijaz

Published in: Current Urology Reports | Issue 10/2014

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Abstract

A literature review of the most current publications studying lower urinary tract symptoms (LUTS) and findings in diabetic women was conducted including articles from January 2013 to April 2014. Current reports consistently note that aging and obesity are significantly associated with worsened LUTS in diabetic women. Glucosuria has variable effects on urodynamic parameters and LUTS, but has a significant association with urinary tract infection (UTI) and incontinence at clinically relevant numbers, such as HbA1C values. The presence of severe nocturia in diabetic patients warrants careful surveillance for cardiovascular risks given the significant association with mortality. Diabetics appear to be at higher risk for colonization with the virulent, extended-spectrum, β-lactamase-producing Escherichia coli and Klebsiella species in UTI. Novel therapies in glycemic control and for diabetic bladder dysfunction are undergoing animal model trials with encouraging results. The most promising of these includes stem cell therapy, although a need exists for human studies.
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Metadata
Title
Lower Urinary Tract Symptoms in Women with Diabetes Mellitus: A Current Review
Authors
Rebecca James
Adonis Hijaz
Publication date
01-10-2014
Publisher
Springer US
Published in
Current Urology Reports / Issue 10/2014
Print ISSN: 1527-2737
Electronic ISSN: 1534-6285
DOI
https://doi.org/10.1007/s11934-014-0440-3

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