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01-11-2012 | Brief Report

Low-level laser therapy for oral mucous membrane pemphigoid

Authors: Adriana Cafaro, Roberto Broccoletti, Paolo Giacomo Arduino

Published in: Lasers in Medical Science | Issue 6/2012

Excerpt

Mucous membrane pemphigoid (MMP) describes a group of chronic, inflammatory, sub epithelial blistering diseases that manifest a heterogeneous pattern of oral, ocular, skin, genital, nasopharyngeal, oesophageal, and laryngeal lesions. MMP is histologically characterized by linear deposition of IgG, IgA, or C3 along the epithelial basement membrane zone (BMZ). Autoantibodies against various epithelial BMZ components probably play a role in the pathogenesis of this group of diseases [1, 2]. MMP does not have a predictable natural history. In some patients, the disease is localized and has a slowly progressive course without complications; in others, it is devastating, with severe morbidity. There have been no large-scale, well-controlled studies regarding therapy for MMP and most of the therapeutic experience is from studies on cutaneous bullous pemphigoid [3]. The choice of agents for its treatment is mainly based upon the sites of involvement, clinical severity, and disease progression [3]. Usually, limited oral lesions are treated with topical immunosuppressive drugs. …

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Title: Low-level laser therapy for oral mucous membrane pemphigoid
Authors: Adriana Cafaro
Roberto Broccoletti
Paolo Giacomo Arduino
Publication date: 01-11-2012
Publisher: Springer-Verlag
Published in: Lasers in Medical Science / Issue 6/2012
Print ISSN: 0268-8921
Electronic ISSN: 1435-604X
DOI: https://doi.org/10.1007/s10103-012-1137-9

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Low-level laser therapy for oral mucous membrane pemphigoid

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