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Published in: Surgical Endoscopy 1/2014

01-01-2014

Long-term outcomes of reintervention for failed fundoplication: redo fundoplication versus Roux-en-Y reconstruction

Authors: Se Ryung Yamamoto, Masato Hoshino, Kalyana C. Nandipati, Tommy H. Lee, Sumeet K. Mittal

Published in: Surgical Endoscopy | Issue 1/2014

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Abstract

Background

Redo fundoplication (RF) is the mainstay of treatment for failed fundoplication. A subset of patients with failed fundoplication requires Roux-en-Y reconstruction (RNY) for symptom relief. The aim of this study was to compare the long-term subjective outcomes between RF and RNY in patients with failed fundoplication.

Methods

After Institutional Board Review approval, retrospective review of a prospective database identified 119 RF (mean = 54.1 years, 78 women) and 64 RNY (mean = 54.8 years, 35 women) patients who underwent reoperative surgery between December 2003 and September 2009. Data variables analyzed included demographics, esophageal manometry, 24-h pH study, type of procedure, perioperative findings, complications, pre- and postoperative symptom (heartburn, regurgitation, dysphagia, and chest pain) scores (scale 0–3), and patient satisfaction score (scale 1–10). Patients with grade 2 and 3 scores were considered to have significant symptoms.

Results

Patients who underwent RNY had a significantly higher body mass index, higher mean number of risk factors, and higher preoperative severity of heartburn and regurgitation compared to the RF group. Of the 183 patients, long-term (>3 years) follow-up was available for 132 (89 RF and 43 RNY) patients. Symptom severity significantly improved after both procedures, with the exception of dysphagia in the RNY group. Overall, there was no significant difference in patients’ satisfaction between the RF and RNY groups. In subset analysis, patients with morbid obesity, esophageal dysmotility, or ≥4 risk factors have better satisfaction with RNY compared to RF (p = 0.027, 0.031, and 0.045, respectively).

Conclusions

RF and RNY have equally good patient satisfaction at 3 years follow-up. RNY may have improved outcomes in patients who are morbid obese, have esophageal dysmotility, or have four or more risk factors.
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Literature
1.
go back to reference Ronkainen J, Aro P, Storskrubb T, Johansson SE, Lind T, Bolling-Sternevald E, Graffner H, Vieth M, Stolte M, Engstrand L, Talley NJ, Agréus L (2005) High prevalence of gastroesophageal reflux symptoms and esophagitis with or without symptoms in the general adult Swedish population: a Kalixanda study report. Scand J Gastroenterol 40(3):275–285PubMedCrossRef Ronkainen J, Aro P, Storskrubb T, Johansson SE, Lind T, Bolling-Sternevald E, Graffner H, Vieth M, Stolte M, Engstrand L, Talley NJ, Agréus L (2005) High prevalence of gastroesophageal reflux symptoms and esophagitis with or without symptoms in the general adult Swedish population: a Kalixanda study report. Scand J Gastroenterol 40(3):275–285PubMedCrossRef
2.
go back to reference Lafullarde T, Watson DI, Jamieson GG, Myers JC, Game PA, Devitt PG (2001) Laparoscopic Nissen fundoplication: five-year results and beyond. Arch Surg 136:180–184PubMedCrossRef Lafullarde T, Watson DI, Jamieson GG, Myers JC, Game PA, Devitt PG (2001) Laparoscopic Nissen fundoplication: five-year results and beyond. Arch Surg 136:180–184PubMedCrossRef
3.
go back to reference Booth MI, Jones L, Stratford J, Dehn TC (2002) Results of laparoscopic Nissen fundoplication at 2–8 years after surgery. Br J Surg 89:476–481PubMedCrossRef Booth MI, Jones L, Stratford J, Dehn TC (2002) Results of laparoscopic Nissen fundoplication at 2–8 years after surgery. Br J Surg 89:476–481PubMedCrossRef
4.
go back to reference Peters JH, DeMeester TR, Crookes P, Oberg S, de Vos ShoopM, Hagen JA, Bremner CG (1998) The treatment of gastroesophageal reflux disease with laparoscopic Nissen fundoplication: prospective evaluation of 100 patients with “typical” symptoms. Ann Surg 228:40–50PubMedCrossRef Peters JH, DeMeester TR, Crookes P, Oberg S, de Vos ShoopM, Hagen JA, Bremner CG (1998) The treatment of gastroesophageal reflux disease with laparoscopic Nissen fundoplication: prospective evaluation of 100 patients with “typical” symptoms. Ann Surg 228:40–50PubMedCrossRef
5.
go back to reference Pessaux P, Armund JP, Delattre JF, Meyer C, Baulieux J, Mosnier H (2005) Laparoscopic antireflux surgery: five-years results and beyond 1,340 patients. Arch Surg 140:946–951PubMedCrossRef Pessaux P, Armund JP, Delattre JF, Meyer C, Baulieux J, Mosnier H (2005) Laparoscopic antireflux surgery: five-years results and beyond 1,340 patients. Arch Surg 140:946–951PubMedCrossRef
6.
go back to reference Carlson MA, Frantzides CT (2001) Complications and results of primary minimally invasive antireflux procedures: review of 10,735 reported cases. J Am Coll Surg 193(4):428–439PubMedCrossRef Carlson MA, Frantzides CT (2001) Complications and results of primary minimally invasive antireflux procedures: review of 10,735 reported cases. J Am Coll Surg 193(4):428–439PubMedCrossRef
7.
go back to reference Catarci M, Gentileschi P, Papi C, Carrara A, Marrese R, Gaspari AL, Grassi GB (2004) Evidence-based appraisal of antireflux fundoplication. Ann Surg 239:325–337PubMedCrossRef Catarci M, Gentileschi P, Papi C, Carrara A, Marrese R, Gaspari AL, Grassi GB (2004) Evidence-based appraisal of antireflux fundoplication. Ann Surg 239:325–337PubMedCrossRef
8.
go back to reference Luketich JD, Fernando HC, Christie NA, Buenaventura PO, Ikramuddin S, Schauer PR (2002) Outcomes after minimally invasive reoperation for gastroesophageal reflux disease. Ann Thorac Surg 74:328–332PubMedCrossRef Luketich JD, Fernando HC, Christie NA, Buenaventura PO, Ikramuddin S, Schauer PR (2002) Outcomes after minimally invasive reoperation for gastroesophageal reflux disease. Ann Thorac Surg 74:328–332PubMedCrossRef
9.
go back to reference Watson DI, Jamieson GG, Game PA, Williams RS, Devitt PG (1999) Laparoscopic reoperation following failed antireflux surgery. Br J Surg 86:98–101PubMedCrossRef Watson DI, Jamieson GG, Game PA, Williams RS, Devitt PG (1999) Laparoscopic reoperation following failed antireflux surgery. Br J Surg 86:98–101PubMedCrossRef
10.
go back to reference Furnee EJ, Draaisma WA, Broeders MJ, Smout AJPM, Vlek ALM, Gooszen HG (2008) Predictors for symptomatic and objective outcomes after surgical reintervention for failed antireflux surgery. Br J Surg 95:1369–1374PubMedCrossRef Furnee EJ, Draaisma WA, Broeders MJ, Smout AJPM, Vlek ALM, Gooszen HG (2008) Predictors for symptomatic and objective outcomes after surgical reintervention for failed antireflux surgery. Br J Surg 95:1369–1374PubMedCrossRef
11.
go back to reference Kajanchee YS, O’Rourke R, Cassera MA, Gatta P, Hansen PD, Swanstrom LL (2007) Laparoscopic reintervention for failed antireflux surgery. Arch Surg 142(8):785–792CrossRef Kajanchee YS, O’Rourke R, Cassera MA, Gatta P, Hansen PD, Swanstrom LL (2007) Laparoscopic reintervention for failed antireflux surgery. Arch Surg 142(8):785–792CrossRef
12.
go back to reference Legner A, Tsuboi K, Bathla L, Lee T, Morrow LE, Mittal SK (2011) Reoperative antireflux surgery for dysphagia. Surg Endosc 25(4):1160–1167PubMedCrossRef Legner A, Tsuboi K, Bathla L, Lee T, Morrow LE, Mittal SK (2011) Reoperative antireflux surgery for dysphagia. Surg Endosc 25(4):1160–1167PubMedCrossRef
13.
go back to reference Awais O, Luketich JD, Tam J, Irshad K, Schuchert MJ, Landreanu JR, Pennarthur A (2008) Roux-en-Y near esophagojejunostomy for intractable gastroesophageal reflux after antireflux surgery. Ann Thorac Surg 85:1954–1961PubMedCrossRef Awais O, Luketich JD, Tam J, Irshad K, Schuchert MJ, Landreanu JR, Pennarthur A (2008) Roux-en-Y near esophagojejunostomy for intractable gastroesophageal reflux after antireflux surgery. Ann Thorac Surg 85:1954–1961PubMedCrossRef
14.
go back to reference Braghetto I, Csendes A, Burdiles P, Botero F, Korn O (2002) Results of surgical treatment for recurrent postoperative gastroesophageal reflux. Dis Esophagus 15:315–322PubMedCrossRef Braghetto I, Csendes A, Burdiles P, Botero F, Korn O (2002) Results of surgical treatment for recurrent postoperative gastroesophageal reflux. Dis Esophagus 15:315–322PubMedCrossRef
15.
go back to reference Williams VA, Watson TJ, Gellersen O, Feurelin S, Molena D, Sillin LF, Jones C, Peters JH (2007) Gastrectomy as a remedial operation for failed fundoplication. J Gastrointest Surg 11:29–35PubMedCrossRef Williams VA, Watson TJ, Gellersen O, Feurelin S, Molena D, Sillin LF, Jones C, Peters JH (2007) Gastrectomy as a remedial operation for failed fundoplication. J Gastrointest Surg 11:29–35PubMedCrossRef
16.
go back to reference Zainabadi K, Courcoulas AP, Awais O, Raftopoulos I (2008) Laparoscopic revision of Nissen fundoplication to Roux-en-Y gastric bypass in morbidly obese patients. Surg Endosc 22(12):2737–2740PubMedCrossRef Zainabadi K, Courcoulas AP, Awais O, Raftopoulos I (2008) Laparoscopic revision of Nissen fundoplication to Roux-en-Y gastric bypass in morbidly obese patients. Surg Endosc 22(12):2737–2740PubMedCrossRef
17.
go back to reference Mittal SK, Legner A, Tsuboi K, Juhasz A, Bathla L, Lee TH (2013) Roux-en-Y reconstruction is superior to redo fundoplication in subset of patients with failed antireflux surgery. Surg Endosc 27(3):927–935PubMedCrossRef Mittal SK, Legner A, Tsuboi K, Juhasz A, Bathla L, Lee TH (2013) Roux-en-Y reconstruction is superior to redo fundoplication in subset of patients with failed antireflux surgery. Surg Endosc 27(3):927–935PubMedCrossRef
18.
go back to reference Makris KI, Panwar A, Willer BL, Ali AA, Sramek KL, Lee TH, Mittal SK (2012) The role of short-limb Roux-en-Y reconstruction for failed antireflux surgery: a single-center 5-year experience. Surg Endosc 26:1279–1286PubMedCrossRef Makris KI, Panwar A, Willer BL, Ali AA, Sramek KL, Lee TH, Mittal SK (2012) The role of short-limb Roux-en-Y reconstruction for failed antireflux surgery: a single-center 5-year experience. Surg Endosc 26:1279–1286PubMedCrossRef
19.
go back to reference Furnee EJ, Draaisma WA, Broeders IA, Gooszen HG (2009) Surgical reintervention after antireflux surgery: a systematic review of the literature. J Gastrointest Surg 13:1539–1549PubMedCentralPubMedCrossRef Furnee EJ, Draaisma WA, Broeders IA, Gooszen HG (2009) Surgical reintervention after antireflux surgery: a systematic review of the literature. J Gastrointest Surg 13:1539–1549PubMedCentralPubMedCrossRef
20.
go back to reference Raftopoulos I, Awais O, Courcoulas AP, Luketich JD (2004) Laparoscopic gastric bypass after antireflux surgery for the treatment of gastroesophageal reflux in morbidly obese patients: initial experience. Obes Surg 14(10):1373–1380PubMedCrossRef Raftopoulos I, Awais O, Courcoulas AP, Luketich JD (2004) Laparoscopic gastric bypass after antireflux surgery for the treatment of gastroesophageal reflux in morbidly obese patients: initial experience. Obes Surg 14(10):1373–1380PubMedCrossRef
21.
go back to reference Houghton SG, Nelson LG, Swain JM, Nesset EM, Kendrick ML, Thompson GB, Murr MM, Nichols FC, Sarr MG (2005) Is Roux-en-Y gastric bypass safe after previous antireflux surgery?—technical feasibility and postoperative symptom assessment. Surg Obes Relat Dis 1(5):475–480PubMedCrossRef Houghton SG, Nelson LG, Swain JM, Nesset EM, Kendrick ML, Thompson GB, Murr MM, Nichols FC, Sarr MG (2005) Is Roux-en-Y gastric bypass safe after previous antireflux surgery?—technical feasibility and postoperative symptom assessment. Surg Obes Relat Dis 1(5):475–480PubMedCrossRef
22.
go back to reference Patterson EJ, Davis DG, Khajanchee Y, Swanström LL (2003) Comparison of objective outcomes following laparoscopic Nissen fundoplication versus laparoscopic gastric bypass in the morbidly obese with heartburn. Surg Endosc 17(10):1561–1565PubMedCrossRef Patterson EJ, Davis DG, Khajanchee Y, Swanström LL (2003) Comparison of objective outcomes following laparoscopic Nissen fundoplication versus laparoscopic gastric bypass in the morbidly obese with heartburn. Surg Endosc 17(10):1561–1565PubMedCrossRef
23.
go back to reference Nelson LG, Gonzalez R, Haines K, Gallagher SF, Murr MM (2005) Amelioration of gastroesophageal reflux symptoms following Roux-en-Y gastric bypass for clinically significant obesity. Am Surg 71(11):950–953PubMed Nelson LG, Gonzalez R, Haines K, Gallagher SF, Murr MM (2005) Amelioration of gastroesophageal reflux symptoms following Roux-en-Y gastric bypass for clinically significant obesity. Am Surg 71(11):950–953PubMed
24.
go back to reference Kent MS, Luketich JD, Irshad K, Awais O, Alvelo-Rivera M, Churilla P, Fernando HC, Landreneau RJ (2007) Comparison of surgical approaches to recalcitrant gastroesophageal reflux disease in the patient with scleroderma. Ann Thorac Surg 84(5):1710–1715PubMedCrossRef Kent MS, Luketich JD, Irshad K, Awais O, Alvelo-Rivera M, Churilla P, Fernando HC, Landreneau RJ (2007) Comparison of surgical approaches to recalcitrant gastroesophageal reflux disease in the patient with scleroderma. Ann Thorac Surg 84(5):1710–1715PubMedCrossRef
25.
go back to reference Deschamps C, Trastek VF, Allen MS, Pairolero PC, Johnson JO, Larson DR (1997) Long term results after reoperation for antireflux procedures. J Thorac Cardiovasc Surg 113:545–551PubMedCrossRef Deschamps C, Trastek VF, Allen MS, Pairolero PC, Johnson JO, Larson DR (1997) Long term results after reoperation for antireflux procedures. J Thorac Cardiovasc Surg 113:545–551PubMedCrossRef
26.
go back to reference Pennathur A, Awais O, Luketich JD (2010) Minimally invasive redo antireflux surgery: lessons learned. Ann Thorac Surg 89(6):S2174–S2179PubMedCrossRef Pennathur A, Awais O, Luketich JD (2010) Minimally invasive redo antireflux surgery: lessons learned. Ann Thorac Surg 89(6):S2174–S2179PubMedCrossRef
Metadata
Title
Long-term outcomes of reintervention for failed fundoplication: redo fundoplication versus Roux-en-Y reconstruction
Authors
Se Ryung Yamamoto
Masato Hoshino
Kalyana C. Nandipati
Tommy H. Lee
Sumeet K. Mittal
Publication date
01-01-2014
Publisher
Springer US
Published in
Surgical Endoscopy / Issue 1/2014
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI
https://doi.org/10.1007/s00464-013-3154-6

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